Long-term efficacy and safety of cryoballoon ablation of atrial fibrillation: A systematic review and meta-analysis.
Pacing Clin Electrophysiol
; 47(1): 49-57, 2024 01.
Article
en En
| MEDLINE
| ID: mdl-37988273
ABSTRACT
BACKGROUND:
This meta-analysis evaluated long-term efficacy and safety of cryoballoon ablation (CB) of atrial fibrillation (AF).METHODS:
PubMed, Cochrane Library, and Web of Science were searched until July 31, 2023, for published works investigating efficacy and safety of CB of AF in which mean/median follow-up time was not less than 36 months. Safety was assessed by adverse events. Efficacy was assessed by AF recurrence, defined as any atrial arrhythmias lasting more than 30 s.RESULTS:
A total of 19 clinical studies were included. After an average of 58.1 months of follow-up, the overall AF recurrence rate was about 37%. The predictors of recurrence were duration of AF (HR 1.00; 95% CI [1.00 â¼ 1.01]), early recurrence of atrial fibrillation (HR 3.96; 95%CI [1.12 â¼ 14.02]), left atrial diameter (HR 1.04; 95%CI [1.02 â¼ 1.06]), and persistent AF (HR1.47; 95% CI [1.19 â¼ 1.82]). In terms of safety, the incidence of transient phrenic paralysis (PNP) was the highest, about 3%; followed by vascular complications (about 2%); pseudoaneurysm, permanent PNP, and all-cause death was (about 1%); and pericardial effusion and stroke / TIA was very low.CONCLUSION:
CB is associated with low rates of severe complications and reasonable success rates.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Venas Pulmonares
/
Fibrilación Atrial
/
Ablación por Catéter
/
Criocirugía
Tipo de estudio:
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Pacing Clin Electrophysiol
Año:
2024
Tipo del documento:
Article
País de afiliación:
China