Dual functionality of pyrimidine and flavone in targeting genomic variants of EGFR and ER receptors to influence the differential survival rates in breast cancer patients.

Avti, Pramod K; Singh, Jitender; Dahiya, Divya; Khanduja, Krishan L

Avti, Pramod K; Singh, Jitender; Dahiya, Divya; Khanduja, Krishan L.

Afiliación

Avti PK; Department of Biophysics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Singh J; Department of Biophysics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Dahiya D; Department of General Surgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Khanduja KL; Department of Biophysics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Integr Biol (Camb) ; 152023 Apr 11.

Article en En | MEDLINE | ID: mdl-38084900

Asunto(s)

Neoplasias de la Mama; Flavonas; Humanos; Femenino; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/genética; Neoplasias de la Mama/patología; Tasa de Supervivencia; Proteómica; Células HEK293; Receptores ErbB/genética; Receptores ErbB/metabolismo; Receptores ErbB/uso terapéutico; Pirimidinas/uso terapéutico; Flavonas/uso terapéutico; Simulación del Acoplamiento Molecular

Palabras clave

ER and EGFR receptors; aromatic and natural compounds; breast cancer patients; dissociation constant; missense mutation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Flavonas Límite: Female / Humans Idioma: En Revista: Integr Biol (Camb) Asunto de la revista: BIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: India

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