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TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.
Tsai, Yuan-Li; Arias-Badia, Marcel; Kadlecek, Theresa A; Lwin, Yee May; Srinath, Aahir; Shah, Neel H; Wang, Zhi-En; Barber, Diane; Kuriyan, John; Fong, Lawrence; Weiss, Arthur.
Afiliación
  • Tsai YL; Rosalind Russell and Ephraim P. Engleman Rheumatology Research Center, Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Arias-Badia M; Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Kadlecek TA; Rosalind Russell and Ephraim P. Engleman Rheumatology Research Center, Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Lwin YM; Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Srinath A; Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Shah NH; Department of Chemistry, Columbia University, New York, NY 10027, USA.
  • Wang ZE; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Barber D; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Kuriyan J; Department of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA.
  • Fong L; Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Weiss A; Rosalind Russell and Ephraim P. Engleman Rheumatology Research Center, Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: arthur.weiss@ucsf.edu.
Immunity ; 56(12): 2682-2698.e9, 2023 Dec 12.
Article en En | MEDLINE | ID: mdl-38091950
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T / Transducción de Señal Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T / Transducción de Señal Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos