The Proton of Alcohols as Hydrogen Source in Diboron-Mediated Nickel-Catalyzed Asymmetric Transfer Hydrogenation of Cyclic N-Sulfonyl Imines.
J Org Chem
; 89(1): 710-718, 2024 Jan 05.
Article
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| MEDLINE
| ID: mdl-38101332
ABSTRACT
The proton of alcohols as the sole hydrogen source in diboron-mediated nickel-catalyzed asymmetric transfer hydrogenation of cyclic N-sulfonyl imines has been developed, providing the chiral cyclic sulfamidates in excellent enantioselectivities. The mechanistic investigations suggested that the proton of alcohols could be activated by tetrahydroxydiboron to form active nickel hydride species.
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Colección:
01-internacional
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MEDLINE
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En
Revista:
J Org Chem
Año:
2024
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Article