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Reference values for nerve conduction studies of the peroneal, tibial, and sural nerve derived from a large population-based cohort: Associations with demographic and anthropometric characteristics-The Maastricht study.
Hodzelmans, Jurriaan J A; Janssen, Marcus L F; Reulen, Jos P H; Blijham, Paul J; Koster, Annemarie; Stehouwer, Coen D A; Mess, Werner H; Sutedja, Nadia A.
Afiliación
  • Hodzelmans JJA; Department of Clinical Neurophysiology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Janssen MLF; Department of Clinical Neurophysiology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Reulen JPH; School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
  • Blijham PJ; Department of Clinical Neurophysiology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Koster A; Department of Clinical Neurophysiology, Máxima Medical Center, Veldhoven, The Netherlands.
  • Stehouwer CDA; CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
  • Mess WH; Department of Social Medicine, Maastricht University, Maastricht, The Netherlands.
  • Sutedja NA; CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.
Muscle Nerve ; 69(5): 588-596, 2024 May.
Article en En | MEDLINE | ID: mdl-38459960
ABSTRACT
INTRODUCTION/

AIMS:

Nerve conduction studies (NCSs) are widely used to support the clinical diagnosis of neuromuscular disorders. The aims of this study were to obtain reference values for peroneal, tibial, and sural NCSs and to examine the associations with demographic and anthropometric factors.

METHODS:

In 5099 participants (aged 40-79 years) without type 2 diabetes of The Maastricht Study, NCSs of peroneal, tibial, and sural nerves were performed. Values for compound muscle action potential (CMAP) and sensory nerve action potential amplitude, nerve conduction velocity (NCV), and distal latency were acquired. The association of age, sex, body mass index (BMI), and height with NCS values was determined using uni- and multivariate linear regression analyses.

RESULTS:

Detailed reference values are reported per decade for men and women. Significantly lower NCVs and longer distal latencies were observed in all nerves in older and taller individuals as well as in men. In these groups, amplitudes of the tibial and sural nerves were significantly lower, whereas a lower peroneal nerve CMAP was only significantly associated with age. BMI showed a multidirectional association. After correction for anthropometric factors in the multivariate analysis, the association between sex and NCS values was less straightforward.

DISCUSSION:

These values from a population-based dataset could be used as a reference for generating normative values. Our findings show the association of NCS values with anthropometric factors. In clinical practice, these factors can be considered when interpreting NCS values.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Nervio Sural / Diabetes Mellitus Tipo 2 Límite: Aged / Female / Humans / Male Idioma: En Revista: Muscle Nerve Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Nervio Sural / Diabetes Mellitus Tipo 2 Límite: Aged / Female / Humans / Male Idioma: En Revista: Muscle Nerve Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos