Ureteroscopic management in cystinuric patients: long-term results from a tertiary care referral center.
World J Urol
; 42(1): 362, 2024 May 30.
Article
en En
| MEDLINE
| ID: mdl-38814457
ABSTRACT
OBJECTIVE:
To evaluate long-term surgical and functional outcomes of cystinuric patients exclusively treated with Ureteroscopy (URS).METHODS:
Data from patients treated for cystine stones at a single academic center were retrospectively analyzed. The management protocol consisted of (i) treating symptomatic or > 7 mm stones, (ii) multi-staged URS for voluminous stones, (iii) referring patients to a dedicated nephrological clinic. The eGFR was calculated according to the MDRD formula. CKD category was assessed according to the NKF classification. Relevant CKD was defined as CKD category ≥ 3a. Descriptive statistics were used to analyze the cohort data.RESULTS:
Data from 46 cystinuric patients treated with 332 URS were available. Median age at diagnosis and at first URS in our center were 18 and 32 years, respectively. Median follow-up was 101 months. Median number of URS and recurrences per patient were 6 and 2, respectively. The median interval between the first and the last available creatinine level was 64 months. Median first and last eGFR were 72 and 74 mL/min, respectively. Overall, 83% of patients had stable or improved renal function within the study period. Ureteral stricture occurred in 3 (6.5%) patients.CONCLUSIONS:
Cystinuria requires intensive endoscopic management. Most patients treated with URS have stable or improved renal function within a long-term follow-up. CKD is a not neglectable event that potentially occurs at an early stage of life. Current findings should be considered for the surgical management of cystinuric patients.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ureteroscopía
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Cistinuria
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Centros de Atención Terciaria
Límite:
Adolescent
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Adult
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Child
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
World J Urol
/
World j. urol
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World journal of urology
Año:
2024
Tipo del documento:
Article
País de afiliación:
Italia