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A Rare Case of Eccrine Carcinoma Demonstrating Intracranial Invasion in a Patient With Advanced Hepatocellular Carcinoma.
Dossani, Haroon A; Irshad, Omayr M; Ibrahim, Bassel; Shine, Billie; Mallick, Jayati; Saleem, Arsalan.
Afiliación
  • Dossani HA; Vascular and Interventional Radiology, University of Texas Medical Branch at Galveston, Galveston, USA.
  • Irshad OM; Vascular and Interventional Radiology, University of Texas Medical Branch at Galveston, Galveston, USA.
  • Ibrahim B; Vascular and Interventional Radiology, University of Texas Medical Branch at Galveston, Galveston, USA.
  • Shine B; Pathology, University of Texas Medical Branch at Galveston, Galveston, USA.
  • Mallick J; Pathology, University of Texas Medical Branch at Galveston, Galveston, USA.
  • Saleem A; Vascular and Interventional Radiology, University of Texas Medical Branch at Galveston, Galveston, USA.
Cureus ; 16(7): e63760, 2024 Jul.
Article en En | MEDLINE | ID: mdl-39100054
ABSTRACT
Eccrine carcinoma (EC) is a rare intraepidermal carcinoma of the eccrine sweat glands. Even more rare are instances of EC exhibiting intracranial invasion. Here, we describe the case of a metachronous EC mass demonstrating intracranial invasion in a patient with advanced-stage hepatocellular carcinoma (HCC), reporting CT head findings of a left frontal skull expansile destructive mass with soft tissue density and immunostain findings of the following CEA positive, granular, EMA positive, AE1/AE3 positive, CK7 strongly positive, CK20 negative, GCDFP negative, and HEPAR negative. The only recommended treatment for EC is surgical excision with tumor-free margins, and no chemotherapy protocols currently exist. Due to socioeconomic factors, our patient was unable to receive adequate treatment for her HCC, nor surgical excision for her EC. However, the unique presentation of a rare intracranial EC tumor causing no neurological deficits in a patient with untreated HCC merits the need for a more thorough identification of secondary tumors via biopsy in patients with HCC to identify possible associations between these two tumors in future patients.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos