<i>S</i>-Alkylated quinazolin-4(3<i>H</i>)-ones as dual EGFR/VEGFR-2 kinases inhibitors: design, synthesis, anticancer evaluation and docking study.

Tawfik, Samar S; Hamdi, Abdelrahman; Ali, Ahmed R; Elgazar, Abdullah A; El-Shafey, Hamed W; El-Azab, Adel S; Bakheit, Ahmed H; Hefnawy, Mohamed M; Ghabbour, Hazem A; Abdel-Aziz, Alaa A-M

S-Alkylated quinazolin-4(3H)-ones as dual EGFR/VEGFR-2 kinases inhibitors: design, synthesis, anticancer evaluation and docking study.

Tawfik, Samar S; Hamdi, Abdelrahman; Ali, Ahmed R; Elgazar, Abdullah A; El-Shafey, Hamed W; El-Azab, Adel S; Bakheit, Ahmed H; Hefnawy, Mohamed M; Ghabbour, Hazem A; Abdel-Aziz, Alaa A-M.

Afiliación

Tawfik SS; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University Mansoura 35516 Egypt drsamarelmasry@mans.edu.eg Abdelrahmanhamdi2012@mans.edu.eg.
Hamdi A; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University Mansoura 35516 Egypt drsamarelmasry@mans.edu.eg Abdelrahmanhamdi2012@mans.edu.eg.
Ali AR; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University Mansoura 35516 Egypt.
Elgazar AA; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University Kafr El Sheikh Egypt.
El-Shafey HW; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University Mansoura 35516 Egypt drsamarelmasry@mans.edu.eg Abdelrahmanhamdi2012@mans.edu.eg.
El-Azab AS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University P. O. Box 2457 Riyadh 11451 Saudi Arabia.
Bakheit AH; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University P. O. Box 2457 Riyadh 11451 Saudi Arabia.
Hefnawy MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University P. O. Box 2457 Riyadh 11451 Saudi Arabia.
Ghabbour HA; School of Health and Biomedical Sciences, RMIT University Melbourne 3083 Australia.
Abdel-Aziz AA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University P. O. Box 2457 Riyadh 11451 Saudi Arabia.

RSC Adv ; 14(36): 26325-26339, 2024 Aug 16.

Article en En | MEDLINE | ID: mdl-39165788

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: RSC Adv Año: 2024 Tipo del documento: Article

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: RSC Adv Año: 2024 Tipo del documento: Article