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Morphogenesis and ultrastructure of respiratory syncytial virus.
J Virol ; 12(5): 1173-80, 1973 Nov.
Article en En | MEDLINE | ID: mdl-4128827
Respiratory syncytial (RS) virus was grown in Vero cells and fixed for electron microscopy at various stages of maturation. Both filamentous and round or kidney-shaped particles, either with (complete) or without (incomplete) internal structure, were observed. All four morphological forms were identical with respect to their reactivity with ferritin-labeled antibody to RS virus. Freezeetching revealed a structural feature apparently unique for RS virus, namely helical striations around the core on the internal aspect of the envelope. This specific configuration was already detectable during the early stages of viral differentiation of the host cell membrane. Concentration of free virus by zonal ultracentrifugation of culture fluids onto sucrose cushions yielded predominantly filamentous forms up to 10 mum in length.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus Sincitiales Respiratorios Límite: Animals / Humans Idioma: En Revista: J Virol Año: 1973 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus Sincitiales Respiratorios Límite: Animals / Humans Idioma: En Revista: J Virol Año: 1973 Tipo del documento: Article