Affinity of human leukocyte interferon for polyribonucleotides.
Cell Biol Int Rep
; 3(8): 663-9, 1979 Nov.
Article
en En
| MEDLINE
| ID: mdl-41640
ABSTRACT
Human leukocyte interferon (HL-IF)binds to AGPOLY(A)TM, AGPOLY(U)TM and AGPOLY(I)TM. The bound interferon could be displaced from all three polyribonucleotides by including sodium chloride in the eluant. The nature of interaction of HL-IF with polyribonucleotides is electrostatic and not hydrophobic since its binding was not prevented in the presence of 50% ethylene glycol. The binding of HL-IF on AGPOLY(I)TM is stronger at lower pH since an increase in ionic strength is required to displace it.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Polirribonucleótidos
/
Virus de la Enfermedad de Newcastle
/
Interferones
/
Leucocitos
Límite:
Humans
Idioma:
En
Revista:
Cell Biol Int Rep
Año:
1979
Tipo del documento:
Article