Lewy bodies of Parkinson's disease contain neurofilament antigens.
Science
; 221(4615): 1082-4, 1983 Sep 09.
Article
en En
| MEDLINE
| ID: mdl-6308771
ABSTRACT
The Lewy body, a histological hallmark of Parkinson's disease, is a filamentous inclusion residing most prominently in pigmented neurons of the brainstem. Immunocytochemical reactions of Lewy bodies were examined with antisera to several filamentous proteins of the nervous system and positive reactions were found with those against neurofilaments. An abnormal organization of the neuronal cytoskeleton may be a pathological feature of Parkinson's disease.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedad de Parkinson
/
Cuerpos de Inclusión
/
Proteínas de Filamentos Intermediarios
Límite:
Humans
Idioma:
En
Revista:
Science
Año:
1983
Tipo del documento:
Article