Nickel-induced changes and reappraisal of Rosenthal fibers in focal CNS lesions.
J Neuropathol Exp Neurol
; 41(6): 664-75, 1982 Nov.
Article
en En
| MEDLINE
| ID: mdl-6982314
ABSTRACT
Nickel (Ni) wire implants into the CNS of Lewis rats induce the formation of structures morphologically similar to Rosenthal fibers (RF) seen in human conditions. We describe in detail the time courses of Ni-induced changes in rat astrocytes and compare the Ni-induced RF with RF occurring in focal lesions. Immunocytochemistry at the level of electron microscopy suggests that the Ni-induced RF are largely made up of plasma proteins. We suggest that the mechanism of RF formation and possibly the protein composition of RF depends on the condition in which they are found.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Encefalopatías
/
Astrocitos
/
Níquel
Límite:
Animals
Idioma:
En
Revista:
J Neuropathol Exp Neurol
Año:
1982
Tipo del documento:
Article