Evaluation of neutrophil and lymphocyte function in subjects with iron deficiency.
S Afr Med J
; 59(4): 111-3, 1981 Jan 24.
Article
en En
| MEDLINE
| ID: mdl-7455835
ABSTRACT
Neutrophil function was studied in a group of 15 children, 7 with iron deficiency (4 with iron deficiency anaemia) and 8 age-matched controls; by clinical and laboratory criteria, all were uninfected. In a second group of 28 children, 14 iron-deficient (6 with iron deficiency anaemia) and 14 controls, numbers of circulating T and B lymphocytes and responsiveness to the mitogens phytohaemagglutinin and concanavalin A were assessed. Levels of salivary IgA were estimated in every patient. Neutrophil chemotaxis to autologous endotoxin-activated serum and control serum, phagocytosis of Candida albicans and post-phagocytic nitro-blue tetrazolium reduction were similar in both the iron-deficient and control groups. Likewise, levels of secretory IgA, serum immunoglobulins, total haemolytic complement and complement components, and numbers of T and B lymphocytes were comparable in both iron-deficient groups and the control group. However, transformation to both mitogens was reduced in the group with iron deficiency anaemia.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Linfocitos
/
Anemia Hipocrómica
/
Neutrófilos
Tipo de estudio:
Clinical_trials
Límite:
Humans
/
Infant
Idioma:
En
Revista:
S Afr Med J
Año:
1981
Tipo del documento:
Article