Auditory event-related brain potentials in autistic children and three different control groups.
Biol Psychiatry
; 38(3): 150-65, 1995 Aug 01.
Article
en En
| MEDLINE
| ID: mdl-7578658
ABSTRACT
ERPs to auditory stimuli, generated during an oddball task, were obtained in a group of autistic children and three control groups (normal, ADDH, and dyslectic children, respectively). The task included the presentation of standards, deviants, and novels and had a (between-group) passive vs. active (counting) condition. It was examined whether 1) it was possible to replicate several earlier findings, 2) autistics manifest an abnormal lateralization pattern of ERPs, 3) autistics have an abnormal mismatch negativity (MMN), and 4) differences between autistics and normals are really specific to the autistic group. The only finding that could be replicated was that autistics have a smaller A/Pcz/300. There was no evidence for abnormal lateralization or abnormal MMN; however, there was an unexpected effect of the task manipulation on the amplitude of the P3 in autistics, the occipital P3 to deviant stimuli was significantly larger in the active than in the passive condition, a finding, like the replication of the smaller A/Pcz/300, specific to the autistic group. It was suggested that the auditory occipital task effect is related to understimulation of the occipital lobe by visual stimuli in autistic children.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastorno Autístico
/
Potenciales Evocados Auditivos
/
Lóbulo Occipital
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Biol Psychiatry
Año:
1995
Tipo del documento:
Article
País de afiliación:
Países Bajos