Freeze-fracture electron microscopy of human erythrocytes lacking the major membrane sialoglycoprotein.
Biochim Biophys Acta
; 464(3): 635-9, 1977 Feb 04.
Article
en En
| MEDLINE
| ID: mdl-836829
Human erythrocytes of blood group En (a-), a rare homozygous condition involving a complete lack of the major sialoglycoprotein of the cell membrane (glycophorin A), were compared with erythrocytes from normal (En (a+)) individuals by freeze-fracture electron microscopy. No decrease in number, or variation in morphology, of the intramembranal particles of En (a-) cells was detectable. The results show that the erythrocyte sialoglycoprotein is not essential for the maintenance of the integrity of the intramembranal particles of the human erythrocyte membrane.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sialoglicoproteínas
/
Membrana Eritrocítica
/
Eritrocitos
/
Proteínas de la Membrana
Límite:
Humans
Idioma:
En
Revista:
Biochim Biophys Acta
Año:
1977
Tipo del documento:
Article