Antibody-based immunological therapies.
Curr Opin Immunol
; 9(5): 717-22, 1997 Oct.
Article
en En
| MEDLINE
| ID: mdl-9368782
ABSTRACT
Clinical research in the area of antibody-based tumor-targeted therapy has been driven for many years by the prospect of identifying cell surface antigens with sufficient restrictive tissue expression patterns to allow for the selective and specific accumulation of antibody in tumor tissue. Few, if any, such antibody-antigen systems have been identified which can effectively deliver a large fraction of an administered therapeutic agent to metastatic cancer. Despite this limitation, however, a greater understanding of the biological and physiological principles of tumor-targeted therapy has resulted in successful antibody-based therapy of lymphoma, colon cancer and breast cancer in recent clinical trials.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Inmunoterapia
/
Anticuerpos Antineoplásicos
/
Neoplasias
Límite:
Humans
Idioma:
En
Revista:
Curr Opin Immunol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Australia