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1.
Artigo em Espanhol | LILACS, BNUY, UY-BNMED | ID: biblio-1568770

RESUMO

La evaluación de la marcha en cinta caminadora puede resultar relevante para la toma de decisiones clínicas. No obstante, factores demográficos como la edad y el IMC pueden alterar la interpretación de los resultados. Nuestro objetivo fue obtener variables espacio- temporales, energéticas y costo de transporte durante la velocidad autoseleccionada en cinta caminadora para una muestra representativa de adultos uruguayos (n=28) y evaluar si diferentes rangos de edades e IMC pueden ser factores a tener en cuenta en pruebas clínicas donde se consideren dichas variables. Participaron 17 hombres y 11 mujeres (39,3 ± 14,8 años, 75,9 ± 12,5 kg, 1,74 ± 0,09 m, IMC 25,2 ± 4,06). Se realizó una reconstrucción 3D del movimiento en forma sincronizada con el consumo energético. Se obtuvieron valores de referencia y luego de agrupar los participantes según su IMC y rango de edad se compararon los datos mediante test de t (p≤0.05). Los resultados revelaron discrepancias significativas en las medidas espacio-temporales y energéticas de los adultos uruguayos al caminar en cinta con respecto a la literatura. La marcha difiere entre adultos jóvenes y de mediana edad en su velocidad autoseleccionada (p=0,03), longitud de zancada (p=0,01), trabajo mecánico externo (<0,001) y recuperación de energía mecánica (0,009), destacando la importancia de considerar la edad en evaluaciones clínicas. El IMC no influyó significativamente en estas variables. Estos hallazgos subrayan la necesidad de ajustar las interpretaciones de las pruebas clínicas de la marcha sobre cinta caminadora en adultos uruguayos de mediana edad (45 a 65 años).


Treadmill gait assessment can be relevant for clinical decision-making. However, demographic factors such as age and BMI may alter result interpretation. Our aim was to obtain spatiotemporal, energetic, and cost of transport variables during self-selected treadmill walking speed for a representative sample of Uruguayan adults (n=28) and to assess if different age ranges and BMI could be factors to consider in clinical tests involving these variables. Seventeen men and eleven women participated (39.3 ± 14.8 years, 75.9 ± 12.5 kg, 1.74 ± 0.09 m, BMI 25.2 ± 4.06). A synchronized 3D motion reconstruction was performed with energy consumption. Reference values were obtained and data were compared using t-tests (p≤0.05), after grouping participants by BMI and age range. Results revealed significant discrepancies in spatiotemporal and energetic measures of Uruguayan adults walking on the treadmill, compared to the literature. Gait differed between young and middle-aged adults in their self-selected speed (p=0.03), stride length (p=0.01), external mechanical work (p<0.001), and mechanical energy recovery (0.009), emphasizing the importance of considering age in clinical evaluations. BMI did not significantly influence these variables. These findings underscore the need to adjust interpretations of treadmill gait clinical tests in middle-aged Uruguayan adults (45 to 65 years).


A avaliação da marcha na esteira pode ser relevante para a tomada de decisões clínicas. No entanto, fatores demográficos como idade e IMC podem alterar a interpretação dos resultados. Nosso objetivo foi obter variáveis espaço-temporais, energéticas e custo de transporte durante a velocidade de caminhada autoselecionada na esteira para uma amostra representativa de adultos uruguaios (n = 28) e avaliar se diferentes faixas etárias e IMC podem ser fatores a serem considerados em testes clínicos que envolvam essas variáveis. Dezessete homens e onze mulheres participaram (39,3 ± 14,8 anos, 75,9 ± 12,5 kg, 1,74 ± 0,09 m, IMC 25,2 ± 4,06). Foi realizada uma reconstrução tridimensional do movimento sincronizada com o consumo de energia. Foram obtidos valores de referência e os dados foram comparados usando testes t (p≤0,05), após agrupar os participantes por IMC e faixa etária. Os resultados revelaram discrepâncias significativas nas medidas espaço-temporais e energéticas dos adultos uruguaios ao caminhar na esteira, em comparação com a literatura. A marcha diferiu entre adultos jovens e de meia-idade em sua velocidade autoselecionada (p=0,03), comprimento da passada (p=0,01), trabalho mecânico externo (<0,001) e recuperação de energia mecânica (0,009), destacando a importância de considerar a idade em avaliações clínicas. O IMC não influenciou significativamente essas variáveis. Esses achados destacam a necessidade de ajustar as interpretações dos testes clínicos de marcha na esteira em adultos uruguaios de meia- idade (45 a 65 anos).


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Composição Corporal/fisiologia , Caminhada/fisiologia , Teste de Esforço/estatística & dados numéricos , Índice de Massa Corporal , Distribuição por Idade
2.
Int J Med Sci ; 21(11): 2031-2039, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39239544

RESUMO

Background: Firefighters have lower levels of physical activity while on call. It is critical to understand the impact of firefighters' physical activity on arterial stiffness. This study classified groups by physical activity level and combined peripheral vascular monitor measurement to explore the relationships between the level of physical activity and cardiovascular (CV) risk and physical fitness (PF) of firefighters, as well as the acute response to arterial stiffness (AS) following maximal aerobic exercise test (MAET) intervention. Methods: The International Physical Activity Questionnaire (IPAQ) was used to classify the participants into 3 groups: low, moderate, and high level of physical activity group, respectively. A total of 36 participants were recruited, 12 in each group. Participants were assessed for body composition, rest brachial-ankle pulse wave velocity (baPWV), handgrip strength (HGS), maximal oxygen uptake (V̇O2max), and MAET baPWV. Results: In the three groups, significant differences were observed in V̇O2max, HGS, relative fat mass (%FM), body mass index (BMI), muscle mass ratio (MMR), and Rest baPWV (p < 0.05). After maximal aerobic exercise, the MAET baPWV values decreased significantly in all groups (all p < 0.001). Rest baPWV was significantly correlated with firefighters' age, seniority, metabolic equivalents (METs), height and muscle mass (MM) (p < 0.05). Conclusions: Firefighters with high levels of physical activity had better body composition and physical fitness and lower Rest baPWV. In all three groups, baPWV was lower after the MAET than before it. Therefore, regardless of a firefighter's level of physical activity, high-intensity aerobic exercise may have a beneficial effect on arterial stiffness.


Assuntos
Exercício Físico , Bombeiros , Aptidão Física , Rigidez Vascular , Humanos , Rigidez Vascular/fisiologia , Masculino , Adulto , Aptidão Física/fisiologia , Exercício Físico/fisiologia , Análise de Onda de Pulso , Composição Corporal/fisiologia , Teste de Esforço/métodos , Força da Mão/fisiologia , Consumo de Oxigênio/fisiologia , Pessoa de Meia-Idade , Índice de Massa Corporal , Índice Tornozelo-Braço , Feminino , Inquéritos e Questionários
3.
PLoS One ; 19(9): e0307325, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39240856

RESUMO

Determining an athlete's maximal peak power (MPP) is crucial in profiling endurance sports participants. While short (3 to 6 seconds) all-out efforts have been validated for MPP assessment, prior studies mainly involved non-endurance trained athletes. This study aimed to assess the intra- and inter-day reliability of a 6-second Wingate test for MPP determination in endurance athletes. Endurance-trained participants (22 males, 5 females) completed nine 6-second Wingate tests over four days (3 trials at baseline, 2 trials on each subsequent day). Analysis revealed no systematic differences in MPP (F(4.09, 106.3) = 1.88, p = 0.117) or time to peak power (χ2 (8) = 5.23, p = 0.732) across the trials. Reliability, assessed through the intraclass correlation coefficient (ICC) and standard error of measurement (SEM), was excellent across all trials (ICC = 0.95, SEM = 40.0W, SEM% = 3.7%). Absolute reliability improved when selecting the average or the best MPP values from each day (SEM% = 2.7% and 2.9%, respectively). Within-day reliability was consistently rated as excellent, with the best values on the 4th day of tests. No significant differences in MPP values occurred between the first and second 6-second Wingate tests on days 1 to 3, with both trials demonstrating similar reliability values (SEM%: 3.2% vs 2.8%, for the first and second trials, respectively). The test also demonstrated a good sensitivity to detect a meaningful change in MPP values. In conclusion, the 6-second Wingate test proves reliable for determining MPP in endurance-trained athletes. Two trials are recommended on the first day of testing, with a single MPP likely sufficient to determine the athlete's MPP on subsequent days.


Assuntos
Atletas , Teste de Esforço , Resistência Física , Humanos , Masculino , Feminino , Resistência Física/fisiologia , Reprodutibilidade dos Testes , Adulto , Teste de Esforço/métodos , Adulto Jovem
4.
BMC Public Health ; 24(1): 2378, 2024 Sep 02.
Artigo em Inglês | MEDLINE | ID: mdl-39223502

RESUMO

BACKGROUND: There are few studies on the safety of sub-maximal exercise testing of aerobic exercise in apparently healthy Chinese populations. The purpose of this study was to explore the frequency of exercise electrocardiography (ECG) abnormalities and the corresponding exercise intensities, as well as the associated influencing factors, during a symptom-limited stepwise incremental cardiopulmonary exercise test (CPET) in an apparently healthy Chinese population. METHODS: A cross-sectional study was done in four communities, one urban and one rural in the North (Beijing) and in the South (Hezhou, Guangxi) of China from 1 January 2017 to 31 December 2018, respectively. Total of 1642 participants was recruited, 918 were eligible and completed demographic indicators, routine blood indicators, physical activity status, symptom-limited CPET and exercise ECG were included in the analysis. RESULTS: Of the exercise ECG outcomes, 10 (1.1%) were positive and occurred at exercise intensities ≥ 62.50% heart rate reserve (HRR); 44 (4.8%) were equivocal and 864 (94.1%) were normal. Individuals with Cardiovascular Disease Risk Factor (CVDRF) = 3-4 were 2.6 times more likely to have a equivocal and abnormal exercise ECG than those with CVDRF = 0-2. Exercise ECGs of individuals with CVDRF = 5-7 were 5.4 times more likely to be positive and abnormal than exercise ECGs of individuals with CVDRF = 0-2. CONCLUSIONS: The exercise intensity of 62.5% HRR can be used as a safe upper limit for safe participation in exercise in apparently healthy Chinese population; the greater the number of CVDRFs, the greater the likelihood of cardiovascular risk during exercise.


Assuntos
Doenças Cardiovasculares , Eletrocardiografia , Teste de Esforço , Exercício Físico , Fatores de Risco de Doenças Cardíacas , Humanos , Estudos Transversais , Masculino , Feminino , China/epidemiologia , Adulto , Pessoa de Meia-Idade , Exercício Físico/fisiologia , Doenças Cardiovasculares/epidemiologia , População do Leste Asiático
5.
J Cardiovasc Med (Hagerstown) ; 25(10): 731-739, 2024 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-39225077

RESUMO

BACKGROUND: Supraventricular extra beats (SVEB) are frequently observed in athletes but data on significance, prognostic role and correlation with cardiac remodeling are contrasting. It is uncertain whether SVEB may indicate the development of more complex arrhythmias and the need for closer monitoring is undetermined. The aim was to assess the prevalence and clinical significance of BESV in Olympic athletes of different sporting disciplines, evaluating potential correlations with cardiac remodeling and clinical features. METHODS: We enrolled athletes who participated at 2012-2022 Olympic Games, submitted to physical examination, blood tests, echocardiography and exercise tests, categorized into power, skills, endurance and mixed disciplines. RESULTS: We studied 1492 elite athletes: 56% male individuals, mean age 25.8 ±â€Š5.1 years; 29.5% practiced power, 12.3% skills, 21% endurance and 37.2% mixed disciplines. At exercise-stress tests, 6.2% had SVEB, mostly single beats. SVEB were not influenced by anthropometrics or blood test results. They were more common in male individuals (77.4 vs. 54.6%, P < 0.0001) and older athletes (27.1 ±â€Š5.7 vs. 25.7 ±â€Š5.1, P = 0.01). In male athletes with SVEB, higher left atrial volumes were observed (24.2 ±â€Š7.3 vs. 22.2 ±â€Š7.1 ml/m2, P = 0.03). No differences were found in terms of sporting discipline: despite larger left atrial dimensions in aerobic disciplines, SVEB rates were similar in different sporting disciplines (6.1% endurance, 6.3% mixed, 5.2% power and 8.7% skills; P = 0.435). CONCLUSION: SVEB were more common in older, male athletes and associated with higher left atrial volume (especially in male individuals) regardless of sport practiced. Athletes with greater left atrial volume and SVEB are supposed to have higher risk, in middle age, of developing more complex arrhythmias.


Assuntos
Atletas , Humanos , Masculino , Adulto , Atletas/estatística & dados numéricos , Adulto Jovem , Feminino , Prevalência , Esportes/fisiologia , Esportes/estatística & dados numéricos , Remodelação Ventricular , Complexos Atriais Prematuros/fisiopatologia , Complexos Atriais Prematuros/diagnóstico , Complexos Atriais Prematuros/epidemiologia , Fatores de Risco , Ecocardiografia , Frequência Cardíaca , Teste de Esforço , Estudos Transversais , Resistência Física/fisiologia
6.
Physiol Rep ; 12(17): e70034, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39261975

RESUMO

Standard cardiopulmonary exercise testing (CPET) produces a rich dataset but its current analysis is often limited to a few derived variables such as maximal or peak oxygen uptake (V̇O2). We tested whether breath-by-breath CPET data could be used to determine sample entropy (SampEn) in 81 healthy children and adolescents (age 7-18 years old, equal sex distribution). To overcome challenges of the relatively small time-series CPET data size and its nonstationarity, we developed a Python algorithm for short-duration physiological signals. Comparing pre- and post-ventilatory threshold (VT1) CPET phases, we found: (1) SampEn decreased by 9.46% for V̇O2 and 5.01% for V̇CO2 (p < 0.05), in the younger, early-pubertal participants; and (2) HR SampEn fell substantially by 70.8% in the younger and 77.5% in the older participants (p < 0.001). Across all ages, females exhibited greater HR SampEn than males during both pre- and post VT1 CPET phases by 14.10% and 23.79%, respectively, p < 0.01. In females, late-pubertal had 17.6% lower HR SampEn compared to early-pubertal participants (p < 0.05). Breath-by-breath gas exchange and HR data from CPET are amenable to SampEn analysis that leads to novel insight into physiological responses to work intensity, and sex and maturational effects.


Assuntos
Teste de Esforço , Frequência Cardíaca , Troca Gasosa Pulmonar , Humanos , Criança , Masculino , Adolescente , Feminino , Teste de Esforço/métodos , Teste de Esforço/normas , Troca Gasosa Pulmonar/fisiologia , Frequência Cardíaca/fisiologia , Consumo de Oxigênio/fisiologia , Entropia
7.
Sci Rep ; 14(1): 21429, 2024 09 13.
Artigo em Inglês | MEDLINE | ID: mdl-39271732

RESUMO

Mitral regurgitation (MR) is associated with morphological and functional alterations of left atrium (LA) and ventricle (LV), possibly inducing LA-LV misalignment. We aimed to: (1) characterize angulation between LA and mitral annulus from conventional cine MRI data and feature-tracking (FT) contours, (2) assess their associations with functional capacity in MR patients, as assessed by oxygen consumption (peak-VO2) and minute ventilation to carbon dioxide production (VE/VCO2) slope, in comparison with MRI LA/LV strain indices. Thirty-two asymptomatic primary MR patients (56 [40; 66] years, 12 women) underwent cardiac MRI resulting in LA/LV conventional FT-derived strain indices. Then, end-diastolic angles were derived from FT LA contours: (1) α, centered on the LA centre of mass and defined by mitral valve extremities, (2) γ, centered on the mitral ring anterior/lateral side, and defined by LA centre and the other extremity of the mitral ring. Cardiopulmonary exercise testing with simultaneous echocardiography were also performed; peak-VO2 and VE/VCO2 slope were measured. While peak-VO2 and VE/VCO2 slope were not correlated to LA/LV strains, they were significantly associated with angles (α: r = 0.50, p = 0.003 and r = - 0.52, p = 0.003; γ: r = - 0.53, p = 0.002 and r = 0.52, p = 0.003; respectively), independently of age and gender (R2 ≥ 0.29, p ≤ 0.03). In primary MR, the new LA/mitral annulus angles, computed directly from standard-of-care MRI, are better correlated to exercise tolerance than conventional LA/LV strain.


Assuntos
Ventrículos do Coração , Imagem Cinética por Ressonância Magnética , Insuficiência da Valva Mitral , Humanos , Feminino , Masculino , Pessoa de Meia-Idade , Imagem Cinética por Ressonância Magnética/métodos , Insuficiência da Valva Mitral/fisiopatologia , Insuficiência da Valva Mitral/diagnóstico por imagem , Idoso , Ventrículos do Coração/diagnóstico por imagem , Ventrículos do Coração/fisiopatologia , Adulto , Átrios do Coração/diagnóstico por imagem , Átrios do Coração/fisiopatologia , Teste de Esforço/métodos , Consumo de Oxigênio , Valva Mitral/diagnóstico por imagem , Valva Mitral/fisiopatologia , Ecocardiografia/métodos
8.
Open Heart ; 11(2)2024 Sep 13.
Artigo em Inglês | MEDLINE | ID: mdl-39277185

RESUMO

OBJECTIVE: Routine screening for cardiovascular disease before kidney transplantation remains controversial. This study aims to compare cardiac testing rates in patients with end-stage renal disease, referred and not referred for transplantation, and assess the impact of testing on transplant wait times. METHODS: This is a retrospective cohort study of 22 687 end-stage renal disease patients from 2011 to 2022, within an integrated health system. Cardiac testing patterns, and the association between cardiac testing and transplant wait times and post-transplant mortality were evaluated. RESULTS: Of 22 687 patients (median age 66 years, 41.1% female), 6.9% received kidney transplants, and 21.0% underwent evaluation. Compared with dialysis patients, transplant patients had a 5.6 times higher rate of stress nuclear myocardial perfusion imaging with single-photon emission (rate ratio (RR) 5.64, 95% CI 5.37 to 5.92), a 6.5 times higher rate of stress echocardiogram (RR 6.51, 95% CI 5.65 to 7.51) and 16% higher cardiac catheterisation (RR 1.16, 95% CI 1.06 to 1.27). In contrast, revascularisation rates were significantly lower in transplant patients (RR 0.46, 95% CI 0.36 to 0.58). Transplant wait times were longer for patients who underwent stress testing (median 474 days with no testing vs 1053 days with testing) and revascularisation (1796 days for percutaneous intervention and 2164 days for coronary artery bypass surgery). No significant association was observed with 1-year post-transplant mortality (adjusted OR 1.99, 95% CI 0.46 to 8.56). CONCLUSIONS: This study found a higher rate of cardiac testing in dialysis patients evaluated for kidney transplants. Cardiac testing was associated with longer transplant wait time, but no association was observed between testing and post-transplant mortality.


Assuntos
Teste de Esforço , Falência Renal Crônica , Transplante de Rim , Listas de Espera , Humanos , Feminino , Masculino , Estudos Retrospectivos , Idoso , Falência Renal Crônica/terapia , Falência Renal Crônica/mortalidade , Falência Renal Crônica/cirurgia , Falência Renal Crônica/diagnóstico , Listas de Espera/mortalidade , Fatores de Tempo , Pessoa de Meia-Idade , Doenças Cardiovasculares/mortalidade , Doenças Cardiovasculares/diagnóstico , Imagem de Perfusão do Miocárdio/métodos , Fatores de Risco , Cuidados Pré-Operatórios/métodos , Seguimentos
9.
Sci Rep ; 14(1): 21522, 2024 09 14.
Artigo em Inglês | MEDLINE | ID: mdl-39277605

RESUMO

Aortic valve replacement (AVR) leads to reverse cardiac remodeling in patients with aortic stenosis (AS). The aim of this secondary pooled analysis was to assess the degree and determinants of changes in myocardial perfusion post AVR, and its link with exercise capacity, in patients with severe AS. A total of 68 patients underwent same-day echocardiography and cardiac magnetic resonance imaging with adenosine stress pre and 6-12 months post-AVR. Of these, 50 had matched perfusion data available (age 67 ± 8 years, 86% male, aortic valve peak velocity 4.38 ± 0.63 m/s, aortic valve area index 0.45 ± 0.13cm2/m2). A subgroup of 34 patients underwent a symptom-limited cardiopulmonary exercise test (CPET) to assess maximal exercise capacity (peak VO2). Baseline and post-AVR parameters were compared and linear regression was used to determine associations between baseline variables and change in myocardial perfusion and exercise capacity. Following AVR, stress myocardial blood flow (MBF) increased from 1.56 ± 0.52 mL/min/g to 1.80 ± 0.62 mL/min/g (p < 0.001), with a corresponding 15% increase in myocardial perfusion reserve (MPR) (2.04 ± 0.57 to 2.34 ± 0.68; p = 0.004). Increasing severity of AS, presence of late gadolinium enhancement, lower baseline stress MBF and MPR were associated with a greater improvement in MPR post-AVR. On multivariable analysis low baseline MPR was independently associated with increased MPR post-AVR. There was no significant change in peak VO2 post-AVR, but a significant increase in exercise duration. Change in MPR was associated with change in peak VO2 post AVR (r = 0.346, p = 0.045). Those with the most impaired stress MBF and MPR at baseline demonstrate the greatest improvements in these parameters following AVR and the magnitude of change in MPR correlated with improvement in peak VO2, the gold standard measure of aerobic exercise capacity.


Assuntos
Estenose da Valva Aórtica , Valva Aórtica , Teste de Esforço , Tolerância ao Exercício , Implante de Prótese de Valva Cardíaca , Humanos , Estenose da Valva Aórtica/cirurgia , Estenose da Valva Aórtica/fisiopatologia , Estenose da Valva Aórtica/diagnóstico por imagem , Masculino , Idoso , Feminino , Tolerância ao Exercício/fisiologia , Teste de Esforço/métodos , Valva Aórtica/cirurgia , Valva Aórtica/fisiopatologia , Valva Aórtica/diagnóstico por imagem , Pessoa de Meia-Idade , Circulação Coronária , Índice de Gravidade de Doença , Ecocardiografia , Imageamento por Ressonância Magnética/métodos
10.
Front Endocrinol (Lausanne) ; 15: 1406930, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39280005

RESUMO

Background: Type 1 diabetes is a chronic autoimmune disease associated with insulin-producing beta cell destruction, declining insulin secretion, and elevated blood glucose. Physical activity improves glycaemic control and cardiovascular health. This study explores acute effects of maximal exhaustion induced by a cardiopulmonary exercise on macro- and microvascular parameters in type 1 diabetes. Methodology: Twenty-five participants with type 1 diabetes (14 males, 11 females), aged 41.4 ± 11.87 years, BMI 23.7 ± 3.08, completed a repeated-measure study. Measurements pre-, post-, 30- and 60-minutes post-exhaustion involved a maximal incremental cardio-pulmonary exercise test. Macro- and microvascular parameters were assessed using VICORDER® and retinal blood vessel image analysis. Repeated measures ANOVA in SPSS (Version 27.0) analysed data. Results: Post-exercise, heart rate increased (p<.001), and diastolic blood pressure decreased (p=.023). Diabetes duration correlated with pulse wave velocity (r=0.418, p=.047), diastolic blood pressure (r=0.470, p=.023), and central retinal arteriolar equivalent (r=0.492, p=.023). Conclusion: In type 1 diabetes, cardiopulmonary exercise-induced exhaustion elevates heart rate and reduces diastolic blood pressure. Future research should explore extended, rigorous physical activity protocols for greater cardiovascular risk reduction.


Assuntos
Diabetes Mellitus Tipo 1 , Exercício Físico , Microvasos , Humanos , Diabetes Mellitus Tipo 1/fisiopatologia , Masculino , Feminino , Adulto , Exercício Físico/fisiologia , Microvasos/fisiopatologia , Pessoa de Meia-Idade , Frequência Cardíaca/fisiologia , Pressão Sanguínea/fisiologia , Teste de Esforço , Glicemia/metabolismo
11.
Trials ; 25(1): 581, 2024 Sep 03.
Artigo em Inglês | MEDLINE | ID: mdl-39227910

RESUMO

BACKGROUND: Branch pulmonary artery (PA) stenosis is one of the most common indications for percutaneous interventions in patients with transposition of the great arteries (TGA), tetralogy of Fallot (ToF), and truncus arteriosus (TA). However, the effects of percutaneous branch PA interventions on exercise capacity remains largely unknown. In addition, there is no consensus about the optimal timing of the intervention for asymptomatic patients according to international guidelines. This trial aims to identify the effects of percutaneous interventions for branch PA stenosis on exercise capacity in patients with TGA, ToF, and TA. In addition, it aims to assess the effects on RV function and to define early markers for RV adaptation and RV dysfunction to improve timing of these interventions. METHODS: This is a randomized multicenter interventional trial. TGA, ToF, and TA patients ≥ 8 years with a class IIa indication for percutaneous branch PA intervention according to international guidelines are eligible to participate. Patients will be randomized into the intervention group or the control group (conservative management for 6 months). All patients will undergo transthoracic echocardiography, cardiac magnetic resonance (CMR) imaging, and cardiopulmonary exercise testing at baseline, 6 months, and 2-4 years follow-up. Quality of life (QoL) questionnaires will be obtained at baseline, 2 weeks post intervention or a similar range for the control group, and 6 months follow-up. The primary outcome is exercise capacity expressed as maximum oxygen uptake (peak VO2 as percentage of predicted). A total of 56 patients (intervention group n = 28, control group n = 28) is required to demonstrate a 14% increase in maximum oxygen uptake (peak VO2 as percentage of predicted) in the interventional group compared to the control group (power 80%, overall type 1 error controlled at 5%). Secondary outcomes include various parameters for RV systolic function, RV functionality, RV remodeling, procedural success, complications, lung perfusion, and QoL. DISCUSSION: This trial will investigate the effects of percutaneous branch PA interventions on exercise capacity in patients with TGA, ToF, and TA and will identify early markers for RV adaptation and RV dysfunction to improve timing of the interventions. TRIAL REGISTRATION: ClinicalTrials.gov NCT05809310. Registered on March 15, 2023.


Assuntos
Tolerância ao Exercício , Cardiopatias Congênitas , Estudos Multicêntricos como Assunto , Artéria Pulmonar , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto , Humanos , Artéria Pulmonar/fisiopatologia , Cardiopatias Congênitas/fisiopatologia , Cardiopatias Congênitas/cirurgia , Resultado do Tratamento , Países Baixos , Estenose de Artéria Pulmonar/fisiopatologia , Estenose de Artéria Pulmonar/etiologia , Estenose de Artéria Pulmonar/diagnóstico por imagem , Função Ventricular Direita , Criança , Fatores de Tempo , Teste de Esforço , Masculino , Recuperação de Função Fisiológica , Tetralogia de Fallot/cirurgia , Tetralogia de Fallot/fisiopatologia , Feminino
12.
J Sports Sci Med ; 23(1): 515-525, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39228769

RESUMO

OpenPose-based motion analysis (OpenPose-MA), utilizing deep learning methods, has emerged as a compelling technique for estimating human motion. It addresses the drawbacks associated with conventional three-dimensional motion analysis (3D-MA) and human visual detection-based motion analysis (Human-MA), including costly equipment, time-consuming analysis, and restricted experimental settings. This study aims to assess the precision of OpenPose-MA in comparison to Human-MA, using 3D-MA as the reference standard. The study involved a cohort of 21 young and healthy adults. OpenPose-MA employed the OpenPose algorithm, a deep learning-based open-source two-dimensional (2D) pose estimation method. Human-MA was conducted by a skilled physiotherapist. The knee valgus angle during a drop vertical jump task was computed by OpenPose-MA and Human-MA using the same frontal-plane video image, with 3D-MA serving as the reference standard. Various metrics were utilized to assess the reproducibility, accuracy and similarity of the knee valgus angle between the different methods, including the intraclass correlation coefficient (ICC) (1, 3), mean absolute error (MAE), coefficient of multiple correlation (CMC) for waveform pattern similarity, and Pearson's correlation coefficients (OpenPose-MA vs. 3D-MA, Human-MA vs. 3D-MA). Unpaired t-tests were conducted to compare MAEs and CMCs between OpenPose-MA and Human-MA. The ICCs (1,3) for OpenPose-MA, Human-MA, and 3D-MA demonstrated excellent reproducibility in the DVJ trial. No significant difference between OpenPose-MA and Human-MA was observed in terms of the MAEs (OpenPose: 2.4° [95%CI: 1.9-3.0°], Human: 3.2° [95%CI: 2.1-4.4°]) or CMCs (OpenPose: 0.83 [range: 0.99-0.53], Human: 0.87 [range: 0.24-0.98]) of knee valgus angles. The Pearson's correlation coefficients of OpenPose-MA and Human-MA relative to that of 3D-MA were 0.97 and 0.98, respectively. This study demonstrated that OpenPose-MA achieved satisfactory reproducibility, accuracy and exhibited waveform similarity comparable to 3D-MA, similar to Human-MA. Both OpenPose-MA and Human-MA showed a strong correlation with 3D-MA in terms of knee valgus angle excursion.


Assuntos
Aprendizado Profundo , Humanos , Reprodutibilidade dos Testes , Adulto Jovem , Masculino , Feminino , Fenômenos Biomecânicos , Articulação do Joelho/fisiologia , Gravação em Vídeo , Adulto , Estudos de Tempo e Movimento , Algoritmos , Teste de Esforço/métodos , Exercício Pliométrico , Amplitude de Movimento Articular/fisiologia , Imageamento Tridimensional
13.
J Sports Sci Med ; 23(1): 638-646, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39228775

RESUMO

The aim of this study was to compare the effects of 8 weeks of small-sided basketball games (SSG) training using baskets (SSGbk) and ball possession games without baskets (SSGbpg) on various neuromuscular parameters in young male basketball players. Specifically, the study examined unilateral isometric knee flexor strength (KFS), unilateral isometric knee extensor strength (KES), bilateral countermovement jump peak power and peak landing force (CMJ), and leg land and hold test (LHT) peak landing force. This randomized controlled study included two experimental groups (SSGbk and SSGbpg) and one control group. Fifty regional competitive-level male youth basketball players (16.7 ± 0.5 years) were assigned to the groups. The experimental groups participated in two additional SSG weekly training sessions over 8 weeks. Both experimental groups were exposed to the same 2v2 to 4v4 formats of play and training volume, with the only difference being that one group performed ball possession games while the other participated in games targeting to score in the basket. Players were evaluated twice: once at baseline in the week prior to the intervention period, and again in the week post-intervention. The neuromuscular tests were conducted using force platforms. Significant interactions between time and groups were observed in KES (p < 0.001; η p 2 = 0.902), KFS (p < 0.001; η p 2 = 0.880), and CMJ peak power (p < 0.001; η p 2 = 0.630). Significant differences between groups were found post-intervention for the variables of KES (p = 0.017; η p 2 = 0.159), KFS (p = 0.011; η p 2 = 0.174), CMJ peak power (p = 0.017; η p 2 = 0.160), CMJ peak landing force (p = 0.020; η p 2 = 0.154), and LHT peak power (p = 0.012; η p 2 = 0.171). In conclusion, our study highlights that the SSGbk significantly increases neuromuscular adaptations in young male basketball players. Conversely, our findings do not support the efficacy of SSGbpg in targeting these specific physical fitness variables. Therefore, the use of SSGs must be carefully considered, particularly in selecting task conditions, to ensure efficacy in interventions.


Assuntos
Desempenho Atlético , Basquetebol , Força Muscular , Humanos , Basquetebol/fisiologia , Masculino , Adolescente , Força Muscular/fisiologia , Desempenho Atlético/fisiologia , Joelho/fisiologia , Condicionamento Físico Humano/métodos , Condicionamento Físico Humano/fisiologia , Músculo Esquelético/fisiologia , Teste de Esforço
14.
J Sports Sci Med ; 23(1): 526-536, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39228777

RESUMO

Despite the well-documented benefits of sprint interval training (SIT) and plyometric training (PT) in improving the physical fitness of soccer players, it remains unclear which of these training methods is superior for enhancing players' aerobic and anaerobic performance. Therefore, this study aimed to compare the effects of SIT and PT on physical performance measures of male soccer players. Thirty male soccer players were randomly assigned to PT (n = 10), SIT (n = 10), and an active control group (CON, n = 10). Before and after the training period, participants underwent a battery of tests consisting of vertical jump, Wingate, linear sprint with and without ball dribbling, change of direction, ball kick, and the Yo-Yo intermittent recovery level 1 (Yo-Yo IR1) tests. Both groups exhibited similar improvements in maximal kicking distance (PT, effect size [ES] = 0.68; SIT, ES = 0.92) and measures of aerobic fitness including maximum oxygen uptake (PT, ES = 1.24; SIT, ES = 1.26) and first (PT, ES = 0.85; SIT, ES = 1.08) and second (PT, ES = 0.86; SIT, ES = 0.98) ventilatory thresholds. However, PT intervention resulted in greater changes in vertical jump (ES = 1.72 vs. 0.82, p = 0.001), anaerobic power (peak power, ES = 1.62 vs. 0.97, p = 0.009; mean power, ES = 1.15 vs. 1.20, p = 0.05), linear speed (20-m, ES = -1.58 vs. -0.98, p = 0.038; 20-m with ball, ES = -0.93 vs. 0.71, p = 0.038), and change of direction ability (ES = -2.56 vs. -2.71, p = 0.046) than SIT. In conclusion, both PT and SIT demonstrated effectiveness in enhancing aerobic performance among male soccer players. However, PT yielded superior improvements in anaerobic power, vertical jump, linear speed, and change of direction performance compared to SIT. These findings suggest that PT may offer additional benefits beyond aerobic conditioning.


Assuntos
Desempenho Atlético , Treinamento Intervalado de Alta Intensidade , Consumo de Oxigênio , Exercício Pliométrico , Futebol , Humanos , Futebol/fisiologia , Masculino , Exercício Pliométrico/métodos , Desempenho Atlético/fisiologia , Adulto Jovem , Treinamento Intervalado de Alta Intensidade/métodos , Corrida/fisiologia , Teste de Esforço , Aptidão Física/fisiologia
15.
J Sports Sci Med ; 23(1): 647-655, 2024 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-39228781

RESUMO

Enhancing peak landing forces and ensuring faster stabilization in the lower limbs during jumping activities can significantly improve performance and decrease the risk of injury among basketball players. This study aimed to compare the effects of unilateral (uPJT) and bilateral plyometric jump training (bPJT) programs on various performance measures, including countermovement jump (CMJ), squat jump (SJ), and single-leg land and hold (SLLH) test outcomes, assessed using force plates. A randomized multi-arm study design was employed, comprising two experimental groups (n = 25; uPJT and n = 25; bPJT) and one control group (n = 25), conducted with youth male regional-level basketball players (16.3 ± 0.6 years old). Participants underwent assessment twice, both before and after an 8-week intervention training period. The uPJT program exclusively involved plyometric drills (e.g., vertical jump exercises; horizontal jump exercises) focusing on single-leg exercises, whereas the bPJT program utilized drills involving both legs simultaneously. The outcomes analyzed included CMJ peak landing force, CMJ peak power, SJ peak force, SJ maximum negative displacement, SLLH time to stabilization, and SLLH peak landing force. The control group exhibited significantly greater SLLH time to stabilization compared to both the uPJT (p < 0.001) and bPJT (p < 0.030) groups. Additionally, time to stabilization was also significantly higher in bPJT than in uPJT (p = 0.042). Comparisons between groups in regards SLLH peak landing force after intervention revealed that the value was significantly smaller in uPJT than in bPJT (p = 0.043) and control (p < 0.001). In the remaining outcomes of CMJ and SJ, both uPJT and bPJT showed significant improvement compared to the control group (p > 0.05), although there was no significant difference between them. In conclusion, our study suggests that utilizing uPJT is equally effective as bPJT in enhancing performance in bilateral jump tests. However, it significantly outperforms bPJT in improving time to stabilization and peak landing forces during single-leg land and hold test. uPJT could be advantageous not for maximizing performance but also for potentially decreasing injury risk by enhancing control and balance during single-leg actions, which are common in basketball.


Assuntos
Desempenho Atlético , Basquetebol , Exercício Pliométrico , Humanos , Basquetebol/fisiologia , Masculino , Exercício Pliométrico/métodos , Adolescente , Desempenho Atlético/fisiologia , Extremidade Inferior/fisiologia , Teste de Esforço/métodos , Fenômenos Biomecânicos , Força Muscular/fisiologia , Perna (Membro)/fisiologia , Condicionamento Físico Humano/métodos , Condicionamento Físico Humano/fisiologia
16.
Eur Respir Rev ; 33(173)2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-39231595

RESUMO

Cardiopulmonary exercise testing (CPET) is a comprehensive and invaluable assessment used to identify the mechanisms that limit exercise capacity. However, its interpretation remains poorly standardised. This scoping review aims to investigate which limitations to exercise are differentiated by the use of incremental CPET in literature and which criteria are used to identify them. We performed a systematic, electronic literature search of PubMed, Embase, Cochrane CENTRAL, Web of Science and Scopus. All types of publications that reported identification criteria for at least one limitation to exercise based on clinical parameters and CPET variables were eligible for inclusion. 86 publications were included, of which 57 were primary literature and 29 were secondary literature. In general, at the level of the cardiovascular system, a distinction was often made between a normal physiological limitation and a pathological one. Within the respiratory system, ventilatory limitation, commonly identified by a low breathing reserve, and gas exchange limitation, mostly identified by a high minute ventilation/carbon dioxide production slope and/or oxygen desaturation, were often described. Multiple terms were used to describe a limitation in the peripheral muscle, but all variables used to identify this limitation lacked specificity. Deconditioning was a frequently mentioned exercise limiting factor, but there was no consensus on how to identify it through CPET. There is large heterogeneity in the terminology, the classification and the identification criteria of limitations to exercise that are distinguished using incremental CPET. Standardising the interpretation of CPET is essential to establish an objective and consistent framework.


Assuntos
Teste de Esforço , Tolerância ao Exercício , Valor Preditivo dos Testes , Humanos , Consumo de Oxigênio , Pulmão/fisiopatologia , Aptidão Cardiorrespiratória , Reprodutibilidade dos Testes
17.
J Cardiopulm Rehabil Prev ; 44(5): 311-316, 2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39230352

RESUMO

PURPOSE: Following acute myocardial infarction (AMI), patients with diabetes mellitus (DM) have a poorer prognosis than those without DM. This study aimed to investigate the benefit of cardiac rehabilitation on cardiorespiratory fitness in patients with AMI, examining whether this effect varied depending on DM and glycated hemoglobin (HbA1c) levels. METHODS: Data were collected from the medical records of 324 patients diagnosed with AMI who were subsequently referred to participate in a supervised exercise-based cardiac rehabilitation program. Cardiorespiratory fitness was assessed using cardiopulmonary exercise testing before and at 3 and 6 mo after the start of cardiac rehabilitation. Linear mixed models were used to evaluate changes in cardiorespiratory fitness between patients with and without DM during the follow-up period. RESULTS: In total, 106 patients (33%) had DM. Both patients with and without DM showed a significant improvement in cardiorespiratory fitness from baseline to the 6-mo follow-up. However, the improvement was significantly lower in patients with DM than in those without DM (1.9 ± 1.5 vs. 3.7 ± 3.2 mL/kg/min, P < .001). Among patients with DM, those with HbA1c levels < 7% showed a greater improvement in cardiorespiratory fitness than those with HbA1c ≥ 7% (2.7 ± 1.5 vs. 1.1 ± 1.8 mL/kg/min, P < .001) during the follow-up period. CONCLUSIONS: Improvements in cardiorespiratory fitness following cardiac rehabilitation were significantly lower in patients with AMI and DM. The response to cardiac rehabilitation in patients is influenced by HbA1c levels. These findings suggest potential implications for individualizing cardiac rehabilitation programming and ensuring optimal glycemic control in patients with AMI and DM.


Assuntos
Reabilitação Cardíaca , Aptidão Cardiorrespiratória , Diabetes Mellitus , Hemoglobinas Glicadas , Infarto do Miocárdio , Humanos , Masculino , Hemoglobinas Glicadas/análise , Feminino , Infarto do Miocárdio/reabilitação , Infarto do Miocárdio/fisiopatologia , Infarto do Miocárdio/sangue , Aptidão Cardiorrespiratória/fisiologia , Pessoa de Meia-Idade , Reabilitação Cardíaca/métodos , Diabetes Mellitus/fisiopatologia , Diabetes Mellitus/sangue , Idoso , Terapia por Exercício/métodos , Teste de Esforço/métodos , Estudos Retrospectivos
18.
J Cardiopulm Rehabil Prev ; 44(5): 317-323, 2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39230364

RESUMO

PURPOSE: Given the difficulty to perform exercise training wearing a mask, we examined differences in functional capacity improvement between masking during the coronavirus disease 2019 (COVID-19) pandemic and non-masking prior to the pandemic for patients undergoing cardiac rehabilitation (CR). METHODS: Records of 660 patients who underwent and completed ≥ 18 sessions of CR in 2018 (n = 318, non-masking) and in 2022 (n = 342, masking) at an academic health system were analyzed. The primary outcome was post-CR change in functional capacity in metabolic equivalents (MET) measured by exercise stress test. Sessions of CR participation and changes in depression, anxiety, and quality of life scores were secondary outcomes. We used multivariable linear regression to adjust for differences in baseline CR outcome measures, demographics, American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR) risk, and comorbid conditions. RESULTS: Baseline age (64.6 ± 0.46 yr), sex (28% female), and racial distribution (85% white) were similar between the masking and non-masking groups. Non-masking patients were more likely to be classified in the AACVPR high risk category and had lower anxiety scores at baseline compared to masking patients. After CR, both groups had similar and significant improvements in depression, anxiety, and quality of life scores, but the improvement in functional capacity was lower in the masking group (-0.62 ± 0.12 MET, P < .001) compared to the non-masking group. Results remained significant after multivariable adjustment. CONCLUSIONS: Cardiac rehabilitation patients requiring masking during the COVID-19 pandemic had less improvement in functional capacity than patients who did not wear masks during CR prior to the pandemic. Interventions to mitigate the potential side effects of masking for CR patients may require further exploration.


Assuntos
COVID-19 , Reabilitação Cardíaca , Máscaras , Qualidade de Vida , Humanos , COVID-19/epidemiologia , Masculino , Feminino , Reabilitação Cardíaca/métodos , Pessoa de Meia-Idade , SARS-CoV-2 , Idoso , Terapia por Exercício/métodos , Tolerância ao Exercício/fisiologia , Ansiedade , Teste de Esforço/métodos , Depressão , Pandemias , Estudos Retrospectivos
19.
Hum Mov Sci ; 97: 103273, 2024 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-39217920

RESUMO

BACKGROUND: This study examined (i) adaptations in muscle activity following perturbation-based balance training (PBT) using treadmill belt-accelerations or PBT using walkway trips and (ii) whether adaptations during treadmill PBT transfer to a walkway trip. METHODS: Thirty-eight older people (65+ years) undertook two PBT sessions, including 11 treadmill belt-accelerations and 11 walkway trips. Surface electromyography (EMG) was measured bilaterally on the rectus femoris (RF), tibialis anterior (TA), semitendinosus (ST) and gastrocnemius medial head (GM) during the first (T1) and eleventh (T11) perturbations. Adaptations (within-subjects - 1st vs 11th perturbations for treadmill and walkway PBT) and their transfer (between-subjects - 1st walkway trip after treadmill PBT vs 1st walkway trip with no prior training) effects were examined for the EMG parameters. RESULTS: Treadmill PBT reduced post-perturbation peak muscle activation magnitude (left RF, TA, ST, right RF, ST, GM), onset latency (right TA), time to peak (right RF) and co-contraction index (knee muscles) (P < 0.05). Walkway PBT reduced post-trip onset latencies (right TA, ST), peak magnitude (left ST, right GM), time to peak (right RF, ST) and pre-perturbation muscle activity (right TA) (P < 0.05). Those who undertook treadmill PBT were not different to those without prior training during the first walkway trip (P > 0.05). CONCLUSIONS: Both treadmill and walkway PBT induced earlier initiation and peak activation of right limb muscles responsible for the first recovery step. Treadmill PBT also reduced co-contraction of the knee muscles. Adaptations in muscle activity following treadmill PBT did not transfer to a walkway trip.


Assuntos
Adaptação Fisiológica , Estudos Cross-Over , Eletromiografia , Músculo Esquelético , Equilíbrio Postural , Humanos , Idoso , Equilíbrio Postural/fisiologia , Masculino , Feminino , Adaptação Fisiológica/fisiologia , Músculo Esquelético/fisiologia , Caminhada/fisiologia , Teste de Esforço , Aceleração , Idoso de 80 Anos ou mais , Fenômenos Biomecânicos/fisiologia
20.
Sensors (Basel) ; 24(17)2024 Sep 02.
Artigo em Inglês | MEDLINE | ID: mdl-39275624

RESUMO

Low-cost, portable devices capable of accurate physiological measurements are attractive tools for coaches, athletes, and practitioners. The purpose of this study was primarily to establish the validity and reliability of Movesense HR+ ECG measurements compared to the criterion three-lead ECG, and secondarily, to test the industry leader Garmin HRM. Twenty-one healthy adults participated in running and cycling incremental test protocols to exhaustion, both with rest before and after. Movesense HR+ demonstrated consistent and accurate R-peak detection, with an overall sensitivity of 99.7% and precision of 99.6% compared to the criterion; Garmin HRM sensitivity and precision were 84.7% and 87.7%, respectively. Bland-Altman analysis compared to the criterion indicated mean differences (SD) in RR' intervals of 0.23 (22.3) ms for Movesense HR+ at rest and 0.38 (18.7) ms during the incremental test. The mean difference for Garmin HRM-Pro at rest was -8.5 (111.5) ms and 27.7 (128.7) ms for the incremental test. The incremental test correlation was very strong (r = 0.98) between Movesense HR+ and criterion, and moderate (r = 0.66) for Garmin HRM-Pro. This study developed a robust peak detection algorithm and data collection protocol for Movesense HR+ and established its validity and reliability for ECG measurement.


Assuntos
Eletrocardiografia , Corrida , Humanos , Masculino , Adulto , Eletrocardiografia/métodos , Corrida/fisiologia , Feminino , Frequência Cardíaca/fisiologia , Reprodutibilidade dos Testes , Ciclismo/fisiologia , Teste de Esforço/métodos , Adulto Jovem
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