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1.
Z Naturforsch C J Biosci ; 78(1-2): 9-25, 2023 Jan 27.
Article in English | MEDLINE | ID: mdl-36069757

ABSTRACT

Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and ß-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.


Subject(s)
Oils, Volatile , Santalum , Humans , Santalum/chemistry , Phytochemicals/pharmacology , Plant Extracts/pharmacology
2.
Oxid Med Cell Longev ; 2022: 6025900, 2022.
Article in English | MEDLINE | ID: mdl-35154569

ABSTRACT

The use of phytochemicals is gaining interest for the treatment of metabolic syndromes over the synthetic formulation of drugs. Senna is evolving as one of the important plants which have been vastly studied for its beneficial effects. Various parts of Senna species including the root, stem, leaves, and flower are found rich in numerous phytochemicals. In vitro, in vivo, and clinical experiments established that extracts from Senna plants have diverse beneficial effects by acting as a strong antioxidant and antimicrobial agent. In this review, Senna genus is comprehensively discussed in terms of its botanical characteristics, traditional use, geographic presence, and phytochemical profile. The bioactive compound richness contributes to the biological activity of Senna plant extracts. The review emphasizes on the in vivo and in vitro antioxidant and anti-infectious properties of the Senna plant. Preclinical studies confirmed the beneficial effects of the Senna plant extracts and its bioactive components in regard to the health-promoting activities. The safety, side effects, and therapeutic limitations of the Senna plant are also discussed in this review. Additional research is necessary to utilize the phenolic compounds towards its use as an alternative to pharmacological treatments and even as an ingredient in functional foods.


Subject(s)
Anti-Infective Agents/adverse effects , Antioxidants/adverse effects , Phytochemicals/adverse effects , Plant Extracts/adverse effects , Plants, Medicinal/chemistry , Senna Plant/chemistry , Animals , Ethnopharmacology/methods , Humans , Medicine, Traditional/adverse effects , Phytotherapy/adverse effects , Plant Components, Aerial/chemistry , Plant Roots/chemistry
3.
Cell Mol Biol (Noisy-le-grand) ; 66(4): 232-242, 2020 Jun 25.
Article in English | MEDLINE | ID: mdl-32583797

ABSTRACT

Natural products interest is gradually increasing worldwide. Plant-food-derived bioactives have a long history of use as a good source of ingredients for valuable medical usages. Plant-based foods consist of micro and macronutrients, and bioactive components, with health-promoting benefits. The handling of complex mixtures of plants has been methodically switched by therapies using a single isolated substance. The delivery of bioactive molecules in nanosystems is enhancing their bioavailability, it is much safer and cost-effective. However, there are many challenges in combining bioactive substances in nanocarrier materials. A discussion related with nanocarriers will be done in this review.


Subject(s)
Biological Products/pharmacology , Food , Nanoparticles/chemistry , Plants/chemistry , Animals , Biological Availability , Humans , Phytochemicals/pharmacology
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