Application of CT imaging texture analysis in predicting simplified pathological types of thymic epithelial tumors / 实用放射学杂志

Objective To investigate the value of CT imaging texture analysis in predicting simplified pathological types of thymic epithelial tumors(TETs).Methods The CT data from 114 patients with TETs confirmed by surgical or pathology were analyzed retrospectivel,and the types of TETs were divided into three groups,including low-risk thymoma(LRT)group,high-risk thymoma(HRT)group,and thymic carcinoma(TC)group.First,the texture parameters of CT images were extracted,and then the weighted Rad-score values were obtained,and the predictive performance of the texture features was evaluated by using the receiver operating characteristic(ROC)curve.Results There were 114 TETs patients,including 45 patients with LRT,44 patients with HRT,and 25 patients with TC.Based on CT imaging texture analysis,the area under the curve(AUC)in differentiating LRT and HRT or TC via CT plain scan,arterial phase,and venous phase were 0.776,0.885,and 0.761,respectively.In differentiating HRT from TC,the AUC of CT plain scan,arterial phase,and venous phase were 0.828,0.808,and 0.804,respectively.In differentiating thymoma from TC,the AUC of CT plain scan,arterial phase,and venous phase were 0.808,0.769,and 0.774,respectively.Conclusion CT imaging texture analysis can serve as an effective auxiliary tool for predicting the simplified pathological types of TETs,helping to develop personal-ized treatment plans for TETs patients.CT enhanced scanning of arterial phase texture parameters has the highest differential diag-nostic efficiency.

Analysis of CT signs of acquired immune deficiency syndrome-associated pneumocystis jirovecii pneumonia / 实用放射学杂志

Objective To explore the common CT signs of acquired immune deficiency syndrome(AIDS)-associated pneumocystis jirovecii pneumonia(PJP).Methods The chest CT data of 123 patients with AIDS-associated PJP were analyzed retrospectively.Results Multifocal lesions in both lungs were found in all cases.Distribution characteristics were as follows:diffuse and symmetrical distribution in both lungs in 100 cases(81.3％),diffuse and asymmetrical distribution in both lungs in 15 cases(12.2％),and scattered distribution in both lungs in 8 cases(6.5％).The density and morphological features were as follows:ground glass opacity in 120 cases(97.6％);"lunate arch sign"in 25 cases(20.3％);pulmonary interstitial proliferation in 103 cases(83.7％);crazy paving pattern in 14 cases(11.4％);patchy or consolidation shadow in 55 cases(44.7％);pulmonary cysts in 26 cases(21.1％);and nodular in 26 cases(21.1％).Other rare signs included pleural effusion in 11 cases,pericardial effusion in 6 cases,mediastinal and hilar lymphadenopathy in 9 cases,and mediastinal emphysema in 1 case.Conclusion The chest CT manifestations of AIDS-associated PJP have certain characteristics,including diffuse and symmetrical distribution of lesions in both lungs,as well as ground glass opacity and interstitial hyperplasia as common signs,especially,"lunate arch sign"and pulmonary cysts are more specific signs.

Analysis of CT dynamic features in invasive pulmonary aspergillosis / 实用放射学杂志

Objective To investigate the initial CT characteristics and dynamic changing features of invasive pulmonary aspergillosis (IPA).Methods CT findings of 40 patients with IPA confirmed by histopathology or clinics were analyzed retrospectively,including the initial and follow-up CT features.Results Multiple lesions in the bilateral lung were found in the initial CT of all 40 patients.The coexistence of no less than two different CT features were showed in 27 patients(67.5 ％),and the same CT morphologic feature were showed in 13 patients (32.5 ％).The common features of the initial CT:nodules/masses (34,85.0 ％),halo sign (24,60.0％),patchy opacities (13,32.5 ％),cavities (9,22.5 ％) and wedge opacities adjacent to pleura (3,7.5 ％).The follow-up CT showed that cavities or air meniscus sign emerged in the nodules/masses after an effective treatment in 29 patients (72.5％) of all 40 cases.The lesion volume decreased subsequent to the collapse of the cavities or air meniscus,and then vanished.Conclusion Thoracic CT scanning play an important role in the diagnosis of IPA.Coexistence of the multiple lesions in number and morphology is the most common CT feature.The findings of follow-up CT is characteristic,and can be helpful in guiding the clinical treatment and evaluating therapeutic effect.