ABSTRACT
Antecedentes: Los bloqueos continuos de los nervios periféricos son de uso común para el manejo del dolor. Sin embargo, la incidencia de desplazamiento o migración del catéter es dudosa, pudiendo ser infraestimada y no denunciarse. Nuestro objetivo fue evaluar el posicionamiento del extremo del catéter supraescapular antes y después de la manipulación rutinaria y simulada mediante fisioterapia de hombro en un modelo cadavérico anatómico.MétodoSe colocaron 8 catéteres para bloqueo continuo y ecoguiado del nervio supraescapular en cadáveres frescos criopreservados. La tomografía computarizada (TC) confirmó la localización de la punta del catéter tras la inyección de 1ml de medio de contraste. Realizamos una serie de movimientos estandarizados de hombro durante una sesión simulada de fisioterapia de hombro en cadáveres. Tras ello, administramos 1ml de azul de metileno a través de los catéteres, y seguidamente realizamos disecciones para identificar con precisión la localización de las puntas del catéter y compararlas con su localización previa a la «fisioterapia».ResultadosLa imagen de la TC confirmó la localización en todos los casos de los extremos del catéter en la muesca supraescapular. Sin embargo, tras la fisioterapia, se encontró que 2 catéteres (25%) habían migrado y, en especial, uno fue localizado en el músculo supraespinoso y el otro en el músculo trapecio.ConclusiónNuestros hallazgos sugieren que el desplazamiento del catéter puede producirse en cerca del 25% de los casos tras la manipulación mediante fisioterapia simulada. Sin embargo, es necesaria más investigación para determinar la incidencia real de los desplazamientos del catéter en la práctica clínica. (AU)
Background: Continuous peripheral nerve blocks are commonly used for pain management. However, the incidence of catheter dislodgement or migration is unclear, and may be underestimated and underreported. Our objective was to assess suprascapular catheter tip positioning before and after routine simulated shoulder physiotherapy manipulation in an anatomical cadaver model.MethodEight ultrasound-guided continuous suprascapular nerve block catheters were placed in cryopreserved fresh cadavers. Computed tomography (CT) confirmed the location of the catheter tip after injection of 1ml of contrast medium. We performed a series of standardized shoulder movements during a simulated shoulder physiotherapy session in cadavers. Following this, we administered 1ml of methylene blue through the catheters, and then performed anatomical dissections to accurately identify the location of the catheter tips and compare them to their placement prior to the physiotherapyResultCT imaging confirmed the location of the catheter tips at the suprascapular notch in all cases. However, following physiotherapy, 2 catheters (25%) were found to have migrated - specifically, 1 was located in the supraspinatus muscle, and the other was located in the trapezius muscle.ConclusionOur findings suggest that catheter dislodgement may occur in approximately 25% of cases following simulated physiotherapy manipulation. However, further research is needed to determine the read incidence of catheter dislodgement in clinical practice. (AU)
Subject(s)
Humans , Tomography , Physical Therapy Modalities , Anatomy , Anesthesia, ConductionABSTRACT
BACKGROUND: Continuous peripheral nerve blocks are commonly used for pain management. However, the incidence of catheter dislodgement or migration is unclear, and may be underestimated and underreported. Our objective was to assess suprascapular catheter tip positioning before and after routine simulated shoulder physiotherapy manipulation in an anatomical cadaver model. METHOD: Eight ultrasound-guided continuous suprascapular nerve block catheters were placed in cryopreserved fresh cadavers. Computed tomography (CT) confirmed the location of the catheter tip after injection of 1â¯ml of contrast medium. We performed a series of standardized shoulder movements during a simulated shoulder physiotherapy session in cadavers. Following this, we administered 1â¯ml of methylene blue through the catheters, and then performed anatomical dissections to accurately identify the location of the catheter tips and compare them to their placement prior to the 'physiotherapy'. RESULT: CT imaging confirmed the location of the catheter tips at the suprascapular notch in all cases. However, following physiotherapy, 2 catheters (25%) were found to have migrated - specifically, 1 was located in the supraspinatus muscle, and the other was located in the trapezius muscle. CONCLUSION: Our findings suggest that catheter dislodgement may occur in approximately 25% of cases following simulated physiotherapy manipulation. However, further research is needed to determine the read incidence of catheter dislodgement in clinical practice.
Subject(s)
Cadaver , Nerve Block , Humans , Nerve Block/methods , Nerve Block/instrumentation , Physical Therapy Modalities , Catheters , Tomography, X-Ray Computed , Ultrasonography, Interventional , Foreign-Body Migration/diagnostic imaging , Foreign-Body Migration/etiology , Male , ShoulderABSTRACT
Introducción: El tratamiento de la capsulitis adhesiva refractaria de hombro es difícil. Este estudio observacional retrospectivo evaluó la efectividad a largo plazo del protocolo de fisioterapia intensiva con bloqueo periférico continuo del nervio supraescapular (BNSE). Método: Revisamos 29 historias clínicas de pacientes con capsulitis adhesiva y les tratamos con fisioterapia intensiva con BNSE durante 10 días. Se registraron los resultados del cuestionario de la escala DASH (Disabilities of the Arm, Shoulder and Hand Outcome Questionnaire) y los movimientos de hombro al inicio, a los 10 días de la infusión de anestésico local y transcurridos tres meses del procedimiento. Resultados: Veintiséis pacientes mejoraron los movimientos de hombro transcurridos 10 días de tratamiento. Se realizó seguimiento completo de 16 pacientes transcurridos tres meses del programa de rehabilitación. El rango de cuatro movimientos de hombro, compatible con una vida diaria normal, fue adquirido por nueve pacientes transcurridos tres meses. No se observó diferencia significativa en términos de movimiento de hombro entre la infusión de AL y transcurridos tres meses. Al finalizar la infusión, la puntuación DASH se redujo significativamente a 59,3 (n=26), y transcurridos tres meses se mantuvo en 42,1 (n=16). A los tres meses, el 33% de la población inicial alcanzó objetivamente los cuatro objetivos, compatibles con una calidad de vida correcta. Conclusión: La rehabilitación con BNSE está asociada a una mejora significativa a largo plazo en términos de movimiento de hombro y calidad de vida en los pacientes con capsulitis adhesiva. Son necesarios ensayos controlados aleatorizados para demostrar nuestros resultados alentadores.(AU)
Introduction: Treatment of refractory adhesive shoulder capsulitis is a challenge. This observational retrospective study evaluated the long-term effectiveness of intensive physiotherapy protocol under a continuous peripheral blockade of the suprascapular nerve (cSSNB). Method: We reviewed 29 medical records of patients suffering from adhesive capsulitis and treated with intensive physiotherapy under cSSNB during 10 days. The disabilities of the arm, shoulder and hand outcome questionnaire (DASH score) and shoulder movements were recorded at the beginning, 10 days after local anesthetic infusion and three months after. Results: Twenty six patients significant improved shoulder movements after 10 days of treatment. Sixteen patients were followed completely until 3 months after rehabilitation program. Range of four shoulder motion compatible with a normal daily life was acquired in nine patients at three months. There is no significant difference in shoulder motion between the end of LA infusion and at three months. At the end of infusion, DASH score is significantly decreased to 59.3 (n=26), and persists three months 42.1 (n=16). At three months, 33% of the initial population objectively reach the 4 goals, compatible with a correct quality of life. Conclusion: Rehabilitation under cSSNB is associated with a significant long term improvement in shoulder motion and quality of life in patients with adhesive capsulitis. Randomized controlled trials will be necessary to demonstrate our encouraging results.(AU)
Subject(s)
Humans , Male , Female , Middle Aged , Rehabilitation , Bursitis/drug therapy , Shoulder Injuries , Physical Therapy Specialty , Shoulder Pain , Anesthesiology , Surveys and Questionnaires , Retrospective StudiesABSTRACT
INTRODUCTION: Treatment of refractory adhesive shoulder capsulitis is a challenge. This observational retrospective study evaluated the long-term effectiveness of intensive physiotherapy protocol under a continuous peripheral blockade of the suprascapular nerve (cSSNB). METHOD: We reviewed 29 medical records of patients suffering from adhesive capsulitis and treated with intensive physiotherapy under cSSNB during 10 days. The "disabilities of the arm, shoulder and hand" outcome questionnaire (DASH score) and shoulder movements were recorded at the beginning, 10 days after local anesthetic infusion and three months after. RESULTS: Twenty six patients significant improved shoulder movements after 10 days of treatment. Sixteen patients were followed completely until 3 months after rehabilitation program. Range of four shoulder motion compatible with a normal daily life was acquired in nine patients at three months. There is no significant difference in shoulder motion between the end of LA infusion and at three months. At the end of infusion, DASH score is significantly decreased to 59.3 (nâ¯=â¯26), and persists three months 42.1 (nâ¯=â¯16). At three months, 33% of the initial population objectively reach the 4 goals, compatible with a correct quality of life. CONCLUSION: Rehabilitation under cSSNB is associated with a significant long term improvement in shoulder motion and quality of life in patients with adhesive capsulitis. Randomized controlled trials will be necessary to demonstrate our encouraging results.
Subject(s)
Bursitis , Nerve Block , Shoulder Joint , Humans , Retrospective Studies , Shoulder , Quality of Life , Range of Motion, Articular/physiology , Bursitis/rehabilitation , Observational Studies as TopicABSTRACT
We here describe the story of a young man who developed a major pneumomediastinum after the removal of a wisdom tooth. The patient was hospitalized in the intensive care unit for continuous monitoring and for the administration of prophylactic antibiotic therapy to avoid infectious complications. Pneumomediastinum after dental procedures has already been reported and its management, although simple, remains subject to major complications if inadequately treated.
Nous décrivons l'histoire d'un jeune patient ayant développé un pneumomédiastin majeur dans les suites de l'extraction d'une dent de sagesse. Ce dernier a été hospitalisé aux soins intensifs afin d'assurer une surveillance continue et d'instaurer une antibioprophylaxie pour éviter les complications infectieuses. Les pneumomédiastins après des soins dentaires ont déjà été rapportés et leur prise en charge, bien que simple, peut mener à des complications majeures si elle est mal réalisée.
Subject(s)
Mediastinal Emphysema , Subcutaneous Emphysema , Chest Pain/etiology , Humans , Male , Mediastinal Emphysema/diagnostic imaging , Mediastinal Emphysema/etiology , Molar, Third/surgery , Subcutaneous Emphysema/etiology , Tooth Extraction/adverse effectsABSTRACT
We describe the case of subcutaneous emphysema that resulted in major respiratory distress. Drainage was performed thanks to the insertion of subcutaneous catheters. This technique has already been described and involves few complications. It represents a potentially easy and lifesaving procedure.
Nous décrivons un cas d'emphysème sous-cutané ayant entraîné une détresse respiratoire majeure. Un drainage décompressif a été réalisé grâce à l'insertion de cathéters sous-cutanés. Cette technique a déjà été décrite et comporte peu de risques et de complications. Elle représente potentiellement un geste simple et salvateur.
Subject(s)
Respiratory Distress Syndrome , Subcutaneous Emphysema , Drainage , Dyspnea , Humans , Respiratory Distress Syndrome/etiology , Subcutaneous Emphysema/complicationsABSTRACT
Traumatic aortic rupture of the thoracic aorta (usually at the isthmus) is frequently associated with concomitant life-threatening injuries. Historically, the conventional care consisted of surgical repair of the lesion performed as soon as possible. However, in spite of constant technical improvements the morbi-mortality remains high because of these associated lesions. In addition, their management can have priority and delay aortic surgery. The endovascular approach has been shown to be a feasible and efficient technique and currently represents a valuable alternative to open surgery for patients with multiple traumas. We report a patient presenting with a traumatic aortic rupture of the aortic isthmus, which was successfully treated by delayed combined endovascular (thoracic aortic stentgrafting) and open approach (hemiaortic arch debranching).
Subject(s)
Aorta, Thoracic/surgery , Aortic Rupture/surgery , Endovascular Procedures/methods , Aorta, Thoracic/injuries , Aorta, Thoracic/pathology , Aortic Rupture/pathology , Female , Humans , Middle Aged , StentsABSTRACT
BACKGROUND: Intraoperative recruitment manoeuvres (RMs) combined with PEEP reverse the decrease in functional residual capacity (FRC) associated with anaesthesia and improve intraoperative oxygenation. Whether these benefits persist after operation remains unknown. We tested the hypothesis that intraoperative RMs associated with PEEP improve postoperative spirometry including FRC and reduce the incidence of postoperative hypoxaemia in morbidly obese (MO) patients undergoing laparoscopic gastric bypass. METHODS: After IRB approval and informed consent, 50 MO patients undergoing laparoscopic gastric bypass under volume-controlled ventilation (tidal volume 6 ml kg(-1) of IBW) were randomly ventilated with either 10 cm H2O PEEP or with 10 cm H2O PEEP and one RM carried out after induction of pneumoperitoneum, and another after exsufflation. Anaesthesia and analgesia were standardized. Spirometry was assessed before operation and 24 h after surgery. Postoperative oxygenation and the apnoea-hypopnoea index (AHI) were recorded during the first postoperative night. RESULTS: Age, BMI, and STOP BANG score were similar in both groups. FRC decrease after surgery was minimal [0.15 (0.14) litre in control and 0.38 (0.19) litre in the RM group] and similar between the groups (P=0.35). FVC, FEV1, mean [Formula: see text], percentage of time spent with [Formula: see text] below 90%, and AHI did not differ significantly between the groups. CONCLUSIONS: This study demonstrates that when added to a protective mechanical ventilation combining low tidal volume and high PEEP, two RMs do not improve postoperative lung function including FRC, arterial oxygenation, and the incidence of obstructive apnoea in MO patients after laparoscopic upper abdominal surgery. CLINICAL TRIAL REGISTRATION: EudraCT 2011-000999-33.
Subject(s)
Gastric Bypass/methods , Hypoxia/prevention & control , Intraoperative Care/methods , Obesity, Morbid/surgery , Positive-Pressure Respiration/methods , Postoperative Complications/prevention & control , Adult , Aged , Carbon Dioxide/analysis , Female , Functional Residual Capacity/physiology , Humans , Hypoxia/complications , Hypoxia/physiopathology , Laparoscopy/methods , Male , Middle Aged , Obesity, Morbid/complications , Spirometry/methods , Spirometry/statistics & numerical data , Tidal Volume/physiology , Young AdultABSTRACT
The effect of overproducing each of the three small heat shock proteins (Hsp; Hsp 18.5, Hsp 18.55, and Hsp 19.3) was investigated in Lactobacillus plantarum strain WCFS1. Overproduction of the three genes, hsp 18.5, hsp 18.55, and hsp 19.3, translationally fused to the start codon of the ldhL gene yielded a protein of approximately 19 kDa, as estimated from Tricine sodium dodecyl sulfate-polyacrylamide gel electrophoresis in agreement with the predicted molecular weight of small Hsps. Small Hsp overproduction alleviated the reduction in growth rate triggered by exposing exponentially growing cells to heat shock (37 or 40 degrees C) and cold shock (12 degrees C). Moreover, overproduction of Hsp 18.55 and Hsp 19.3 led to an enhanced survival in the presence of butanol (1% v/v) or ethanol (12% v/v) treatment suggesting a potential role of L. plantarum small Hsps in solvent tolerance.
Subject(s)
Adaptation, Physiological , Cold Temperature , Heat-Shock Proteins, Small/metabolism , Heat-Shock Response , Lactobacillus plantarum/physiology , Bacterial Proteins/metabolism , Gene Expression Regulation, Bacterial , Hot Temperature , Lactate Dehydrogenases/genetics , Lactobacillus plantarum/growth & development , Recombinant Fusion Proteins/metabolism , SolventsABSTRACT
The case of a pregnant woman in whom hepatitis developed after administration of high-dose fenoterol during the third trimester of a second pregnancy is described.
Subject(s)
Chemical and Drug Induced Liver Injury/etiology , Fenoterol/adverse effects , Pregnancy Complications/chemically induced , Tocolytic Agents/adverse effects , Adult , Female , Fenoterol/therapeutic use , Humans , Pregnancy , Progesterone/therapeutic use , Tocolytic Agents/therapeutic use , Uterine Contraction/drug effectsABSTRACT
A post-mortem histological examination of the eyes of a case of primary hyperoxaluria revealed the presence of crystals in the ciliary processes and at the level of the retinal pigment epithelium. The crystallography study demonstrated that it consisted of wewhellite. The ocular lesions are compared with those found by other authors in primary hyperoxaluria, after prolonged methoxyflurane anaesthesia, after experimental administration of dibutyloxalic acid or naphthalene, and in the human retina in longstanding detachments. Most of the factors which give rise to the presence in the eye of oxalate and its selective precipitation in the midst of certain ocular tissues remain hypothetical. The retinal lesions observed in primary hyperoxaluria appear to be pathognomonic for hyperoxalaemia.