Micro-osteoperforation for enhancement of orthodontic movement: A mechanical analysis using the finite element method.

BACKGROUND: Micro-osteoperforation is a minimally invasive technique aimed at accelerating tooth movement. The goal of this novel experimental study was to assess tooth movement and stress distribution produced by the force of orthodontic movement on the tooth structure, periodontal ligament, and maxillary bone structure, with and without micro-osteoperforation, using the finite element method. MATERIALS AND METHODS: Cone-beam computed tomography was used to obtain a virtual model of the maxilla and simulate the extraction of right and left first premolars. Three micro-osteoperforations (1.5 x 5 mm) were made in the hemiarch on the distal and mesial surfaces of upper canines, according to the power tip geometry of the Propel device (Propel Orthodontics, Ossining, New York, USA). An isotropic model of the maxilla was fabricated according to the finite element method by insertion of mechanical properties of the tooth structures, with orthodontic force (1.5 N) simulation in the distal movement on the upper canine of a hemiarch. RESULTS: Initial movement was larger when micro-osteoperforations were performed on the dental crown (24%) and on the periodontal ligament (29%). In addition, stress distribution was higher on the bone structure (31%) when micro-osteoperforations were used. CONCLUSIONS: Micro-osteoperforations considerably increased the movement of both the dental crown and periodontal ligament, which highlights their importance in the improvement of orthodontic movement, as well as in stress distribution across the bone structure. Important stress absorption regions were identified within micro-osteoperforations.

Bibliometric analysis and diagnostic efficacy of cone-beam computed tomography studies published in Imaging Science in Dentistry from 2011 to 2022.

Purpose: This bibliometric analysis aimed to provide a comprehensive overview of the characteristics, trends, and level of diagnostic efficacy of studies on cone-beam computed tomography (CBCT) published in Imaging Science in Dentistry (ISD) from 2011 to 2022. Materials and Methods: Publications related to CBCT identified in the electronic collection of ISD were selected according to eligibility criteria by 2 independent reviewers who collected data on the characteristics of the articles (year, authors, and country). The type and topic of studies were analyzed using VOSviewer v.1.6.18 (Centre for Science and Technology Studies, Leiden University, Leiden, Netherlands). The research articles were classified according to the hierarchical scale of diagnostic efficacy. Results: Of the 236 articles included, most were from South Korea and Brazil. Bong-Hae Cho and Yun-Hoa Jung were the most prolific authors on the topic of CBCT. The most frequently published types of studies were cross-sectional and laboratory-based. The most popular topics WERE related to the diagnosis of pathologies and/or alterations, as well as anatomical variations. On the diagnostic efficacy scale, most studies were rated level 1 (technical efficacy) or 2 (diagnostic accuracy efficacy). Conclusion: A steady increase was observed in publications related to CBCT, which are of both clinical and academic interest. The trends in these publications were analyzed, revealing that most are cross-sectional studies primarily exploring the capabilities of CBCT in diagnosing pathologies and/or changes in the oral and maxillofacial complex. These studies were typically classified as level 1 or 2 on the diagnostic efficacy scale.

Micro-CT analysis of the mandibular bone microarchitecture of rats after radiotherapy and low-power laser therapy.

To investigate whether low-level laser therapy (LLLT), at different times of application (immediate and late) in the region of the parotid glands, has a distance effect on the microarchitecture of the trabecular bone in mandible of rats irradiated by volumetric modular arc therapy (VMAT). Thirty adult Wistar rats were randomly divided into placebo control groups (CG, n = 2), only radiotherapy (RG, n = 2), only LPLT (LG, n = 2), and two other groups using LLLT in the immediate time (24 h) (ILG, n = 12) and late (120 h) (LLG, n = 12) to radiotherapy by VMAT in a single dose of 12 Gy. LLLT with AsGaAl laser (660 nm, 100 mW), a spot size of 0.0028 cm2, was applied in three points in the region of the right parotid gland, with energy of 2 J/cm2, 20 s per point, for 10 consecutive days. After euthanasia, the right hemimandibles of each animal were dissected, prepared, and analyzed by computerized microtomography (micro-CT) and histomorphometry. The different groups were analyzed by the Tukey and Bonferroni multiple comparison tests. The micro-CT analysis found statistically significant differences between the groups, especially in the LLG, which had the highest average bone volume compared to the CG (p = 0.001) and ILG (p = 0.002) and a greater number of trabeculae than the CG (p = 0.000) and ILG (p = 0.031). The ILG also had a higher number of trabeculae than the CG (p = 0.005). Trabecula separation (Tb.Sp) was lower in the LLG (p = 0.000) and ILG (p = 0.002) when compared to the CG. In the histomorphometry, there was no statistical difference between the groups in relation to all the analyzed variables. Micro-CT analysis showed that the LLLT, even applied at a distance, both in the immediate and late VMAT times, has an effect on the mandibular bone microarchitecture by increasing the volume and number of trabeculae and decreasing the spaces between them.

Estrutura curricular dos cursos de graduação em Odontologia nos países constituintes do Mercosul / Curricular structure of Mercosur countries' Dentistry undergraduate programs

Este estudo objetivouanalisar a organização curricular dos cursos degraduação emOdontologia nos países membros doMercado Comum do Sul (Mercosul), tendo como base a estrutura de agrupamento de conteúdos essenciais estabelecida pela Resolução CNE/CES nº 3, de 19 de fevereiro de 2002e ratificada pela Resolução nº3, de 21 de junho de 2021. A seleção de cursos foirealizada a partir de dados existentes em órgãos governamentais dos diferentes países identificados como universo de estudo, assim como na base de dados Universia. A amostra foiconstituída pelos currículos desses cursosobtidos nos sitesde suas respectivas instituições, sendo 141 cursos incluídos no Brasil, 8 na Argentina, 2 no Paraguaie 2 no Uruguai.As cargas horárias das disciplinas constituintes das matrizes curriculares destes cursos foramsomadas, de acordo com o Artigo 6° das Diretrizes Curriculares Nacionais (DCN) Brasileiras, sendo este subdividido em Ciências Biológicas e da Saúde, Ciências Humanas e Sociais e Ciências Odontológicas. Os dados foram analisados por meio de estatística descritiva. A análise dos resultados permite concluir que hásimilaridade, atual, de estrutura curricular,com algumas características a serem salientadas como a maior carga-horária exigida no Paraguai e a menor, no Brasil. Outros estudos relacionados com a temática, utilizando outras formas de coleta de dados e percursos metodológicos,são imprescindíveis para que se possa avaliar possibilidades de aproximação e trânsito livre de egressos, visando um perfil profissiográfico regional,que favoreça apossibilidade de, no futuro, estabelecer uma estratégia de "formação para a integração"nos Estados Partesdo Mercosul (AU).

This study analyzes the curricular organization of the Dentistry Courses in Mercosur member countries, based on the essential contents'grouping structure, established by the Resolution CNE / CES n. 3 of February 19, 2002. The programs' selection was carried out from existing data of the government agencies of the different countries studied, and in the Universia database. The sample consisted of the curricula of these programs obtained in the websites of their respective institutions, comprising 141 Brazilian programs, 8 Argentinian, 2 Paraguayan, and 2Uruguayan. The hourly loads of the disciplines of the curricular matrices of these courses were added, according to the Article 6 of the "Diretrizes Curriculares Nacionais" (DCN -Brazilian National Curricular Guidelines), which is subdivided into Biological and Health Sciences, Human and Social Sciences, and Dental Sciences. Descriptive statistics were used to analyze the data. The software used for statistical analysis was SPSS version 22.0. The analysis of the results leads to the conclusion that there is currently a similarity inthe countries' curricular structure. Eventual adjustments should be made to achieve a regional professional profile, to establish in the future a strategy of "training for integration" that allows the free passage of Dentistry graduates in Mercosur Member States (AU).

Effect of Radiotherapy and Low-Level Laser Therapy on Circulating Blood Cells of Rats.

Introduction: This study aimed to investigate the effect of low-level laser therapy (LLLT) on the blood cell count when applied to parotid glands of rats irradiated by volumetric modular arc therapy (VMAT). Methods: Thirty-two adult male Wistar rats were used in this study. Samples were randomly assigned to three groups: control group (CG, n = 8), immediate laser group (24 hours) (ILG, n=12), and late laser group (120 hours) (LLG, n=12). The two laser groups were previously subjected to VMAT radiotherapy in a single dose of 12 Gy. LLLT with an AsGaAl laser (660 nm, 100 mW) was applied at three points in the region of the parotid glands, right side, with the energy of 2 J per point (20s, 70 J/cm2) and a spot size of 0.0028 cm2 for 10 consecutive days. In the euthanasia, blood samples were obtained by cardiac puncture. The samples from each group were processed by an automatic method and analyzed for erythrogram, leukogram and platelet count values. The data were analyzed by ANOVA and each LLLT time point was analyzed in relation to the control group, with a significance level less than 0.05. Results: Groups using LLLT had higher red blood cell counts, being higher in the LLG (P = 0.000). The hematimetric indices MCV (P = 0.002) and MCH (P = 0.009) were lower than the control group, especially when compared to the group using LLLT 120h after radiotherapy (LLG). White blood cell counts were lower in the groups with radiotherapy and immediate use of LLLT (ILG) (P = 0.011), mainly at the expense of lymphocytes (P = 0.002). Conclusion: The results suggest a potential systemic effect of LLLT, especially on circulating red blood cell counts, regardless of their time of immediate or late use of radiotherapy.

Evaluation of Aquaporins 1 and 5 Expression in Rat Parotid Glands After Volumetric Modulated Arc Radiotherapy and Use of Low-Level Laser Therapy at Different Times.

Introduction: This experimental study investigated the mRNA expression of aquaporins (AQPs) 1 and 5 in the parotid glands of rats irradiated with volumetric modulated arc therapy (VMAT) and subjected to low-level laser therapy (LLLT) at different time points. Methods: The sample consisted of 30 Wistar rats (Rattus norvegicus) divided into the following groups: control, LLLT alone (LG), radiotherapy alone (RG), and experimental groups that received LLLT at 24 hours (early experimental group [EEG], n=12) and 120 hours (late experimental group [LEG], n=12) after radiotherapy. VMAT was delivered at a single dose (12 Gy) and LLLT was performed with an aluminium-gallium-arsenide diode laser (660 nm, 100 mW), spot area of 0.0028 cm2, energy of 2 J/cm2 applied to 3 spots in the region corresponding to the right parotid gland, for 10 consecutive days. The right parotid gland was resected and prepared for RNA extraction. The gene expression of AQPs was evaluated by quantitative polymerase chain reaction (qPCR) using specific TaqMan probes, with the HPRT gene as an internal control. Results: The lowest AQP1 gene expression was 0.83 (0.27) with the use of LLLT 24 hours after radiotherapy (EEG), and the highest was 1.56 (0.80) with the use of LLLT alone (LG). Likewise, the lowest AQP5 gene expression was found in the EEG (mean = 0.88; SD = 0.49) and the highest in the LG (mean = 1.29; SD = 0.33). Conclusion: The use of LLLT after radiotherapy may contribute to the maintenance and an increase of these proteins, even when used at a later time point after radiotherapy.

Evaluation of 1211 third molars positions according to the Classification of Winter, Pell & Gregory / Evaluación de posiciones de 1211 terceros molares acorde a la Clasificación de Winter, Pell & Gregory

Panoramic radiographs are important for the evaluation and classification of the third molars position, allowing the diagnosis and planning of extraction. The objective of this study is to evaluate upper and lower third molars positions in panoramic radiographs with the classification methods proposed by Pell and Gregory (1933) and Winter (1926) and the subsequent comparison of results with other authors. Panoramic radiographs of 310 patients were analyzed, 197 female and 113 male, totaling 1,211 third molars. In relation to the upper third molars, the most prevalent positions were: angle compared to the long axis of the second molar of Distoangular form (53.23 %) and the depth of impaction as Class C (48.25 %). In the lower third molars, the most prevalent positions were: angle to the long axis of the second molar in Mesioangular classification (52.96 %), the depth of impaction was B (46.54 %) and the tooth relationship with the mandibular ramus was identified as class I (55.26 %). These results provide information that can be utilized in predicting third molar development in terms of impaction or eruption, assisting dental surgeons in making decisions regarding surgical planning and treatment.

Las radiografías panorámicas son importantes para la evaluación y clasificación de la posición de los terceros molares, lo que permite el diagnóstico y la planificación de la extracción. El objetivo de este estudio fue evaluar terceros molares superiores e inferiores y posiciones en las radiografías panorámicas con los métodos de clasificación propuestas por Pell & Gregory, y Winter y la posterior comparación de los resultados con otros autores. Se analizaron las radiografías panorámicas de 310 pacientes, 197 mujeres y 113 hombres, con un total de 1.211 terceros molares. En relación con los terceros molares superiores, las posiciones más prevalentes fueron: ángulo con respecto al eje longitudinal del segundo molar de forma distoangular (53,23 %) y la profundidad de la impactación como Clase C (48,25 %). En los terceros molares inferiores, las posiciones más prevalentes fueron: ángulo con respecto al eje longitudinal del segundo molar en la clasificación mesioangular (52,96 %), la profundidad de impactación fue de B (46,54 %) y la relación de los dientes con la rama mandibular fue identificado como Clase I (55,26 %). Estos resultados proporcionan información que puede ser utilizada para predecir el desarrollo del tercer molar en términos de compactación o erupción, ayudando a los cirujanos dentistas en la toma de decisiones respecto a la planificación y el tratamiento quirúrgico.

Remoção cirúrgica de dentes impactados em posições atípicas / Surgical removal of atypically positioned impacted teeth

Removal of impacted teeth may pose major challenges to the dental surgeon and requires careful surgical planning. The present series describes three clinical cases subjected to surgical extraction of atypically positioned impacted teeth with successful outcomes and no complications. The approach adopted in each case is discussed (AU).

Devido à complexidade para remoção que algumas impactações dentárias podem apresentar, o cirurgião deve estar atento no momento do planejamento cirúrgico. Esta série de 3 casos clínicos mostra o manejo cirúrgico de dentes impactados em posições atípicas que foram tratados com sucesso e sem complicações e discute a forma de abordagem de cada caso (AU).

Clarifying the Impact of Untreated and Treated Dental Caries on Oral Health-Related Quality of Life among Adolescents.

The aim of the present study was to investigate the effect of dental caries experience and the components of the decayed, missing and filled teeth (DMFT) index on oral health-related quality of life (OHRQoL) among adolescents in southern Brazil. A cross-sectional study was conducted with 509 adolescents aged 11-14 years enrolled at public schools in the municipality of Osório (southern Brazil). A calibrated examiner performed the clinical examination for caries (World Health Organization: DMFT index), malocclusion (Dental Aesthetic Index) and traumatic dental injuries [Andreasen et al., 2007]. The participants answered the Brazilian version of the Child Perceptions Questionnaire (CPQ11-14) - Impact Short Form, and their parents/guardians answered a structured questionnaire addressing demographic and socioeconomic characteristics. Data analysis involved Poisson regression with robust variance, with the calculation of rate ratios adjusted for potential confounding variables. High severity of dental caries experience exerted a significant impact on OHRQoL, even after controlling for socioeconomic and clinical factors (rate ratio 1.30; 95% confidence interval, CI 1.12-1.51). All OHRQoL domains were affected by untreated dental caries. The multivariate analysis demonstrated that the CPQ11-14 scores were 33% higher among adolescents with untreated caries (rate ratio 1.33; 95% CI 1.17-1.50) and 24% higher among those with missing teeth (rate ratio 1.24; 95% CI 1.06-1.47). No difference in OHRQoL was found between adolescents with filled teeth and those without dental caries. In conclusion, dental caries experience, untreated dental caries and missing teeth exerted a negative impact on OHRQoL among the adolescents.

A Retrospective Study of Oral and Maxillofacial Injuries in an Emergency Hospital in Southern Brazil

Objective: To identify and analyze cases of OMF treated in an emergency hospital in southern Brazil. Material and Methods: The investigators conducted a retrospective, cross-sectional study. The sample was composed of 1,533 patient medical records. Demographic, seasonal, and clinical variables were collected. Additionally, the medical records also included data on etiological factors, injury site, and tissues involved. A descriptive analysis was conducted based on 1,179 (76.9%) records of OMF injuries. Results: Most patients were male children and adolescents. Accidents (59.7%), such as falls, and interpersonal violence (18.7%), such as physical aggression, were the main etiological factors. Most injuries involved soft tissue (66.4%), especially in the lip region; whereas fractures affected the nasal bones. Transfers and hospitalizations accounted for 8.1% of clinical outcomes and dentists participated in the treatment of 85% of cases. Conclusion: The results of this study suggest a higher prevalence of OMF injuries in men, affecting young people more frequently and showing falls as the main etiological factor. Dentists participated in the majority of the medical care. Future studies will focus on determining risk groups, developing preventive programs, and improving health care services, with the participation of dentists in the multidisciplinary team.

Time interval after radiotherapy and dental implant failure: systematic review of observational studies and meta-analysis.

BACKGROUND: Typically, dental implants are placed in irradiated bone after a delay that exceeds 6 months, but it is not known whether longer delays are beneficial. PURPOSE: The purpose of the study is to review the literature comparing the failure rate of dental implants placed in irradiated bone between 6 and 12 months and after 12 months from the cessation of radiotherapy. MATERIALS AND METHODS: Four electronic databases were searched for articles published until February 2013 without language restriction: Lilacs, Medline, Scopus, and the Cochrane Central Register of Controlled Trials. Two reviewers independently assessed the eligibility criteria and extracted data. Fixed effect meta-analysis was performed. RESULTS: Overall, 3,749 observational studies were identified. After the screening of titles and abstracts, 236 publications were selected, and 10 were included in the final analysis. The pooled relative risk (RR) of failure was RRpooled = 1.34 (95% confidence interval [CI]: 1.01-1.79), higher in individuals who had dental implants installed between 6 and 12 months after receiving radiotherapy. I(2) indicated nearly 21% heterogeneity (p = .25). Egger's test indicated no evidence of publication bias (p = .62); however, the removal of one study significantly affected the overall RR (RRpooled = 1.08, 95% CI: 0.77-1.52). CONCLUSIONS: Placing implants in bone within a period shorter than 12 months after radiotherapy may result in a higher risk of failure; however, additional evidence from clinical trials is needed to verify this risk.

Effect of surface roughness and low-level laser therapy on removal torque of implants placed in rat femurs.

The present study measured removal torque and bone-implant interface resistance of machined implants, acid-etched implants, or machined implants irradiated around the implant area with infrared low-level laser therapy (LLLT; 830 nm) immediately after surgery. There were statistically significant differences between Groups A (control) and B (rough surface) (P = .03). Implants with a rough surface seem to add resistance to the bone-implant interface compared with smooth titanium implants or implants treated with LLLT.

Calcium phosphate cement in orbital reconstructions.

Treatment of facial trauma sequelae is a complex and challenging process. There is still controversy over suitable materials for orbital wall reconstruction. This study evaluated calcium phosphate cement (CPC) implants manufactured by rapid prototyping in the repair of orbital wall defects secondary to trauma. Computed tomographic scans of 5 patients were used for surgery planning and production of CPC implants. Implants were used to restore orbital wall anatomy, ocular alignment, and facial contour. Benefits resulting from the use of implants, such as a reduced operating time, patient response to biomaterial implantation, biomaterial integrity and stability, and patient satisfaction with treatment, were analyzed qualitatively. Our results suggest that CPC is an effective and safe material for orbital reconstruction because of its biocompatibility and easy production and placement.

Worldwide incidence of odontogenic tumors.

PURPOSE: The objective of the study was to determine the relative frequency of odontogenic tumors (OTs) in the world population, directing an epidemiologic profile to these lesions. METHODS: Was conducted a search in epidemiologic studies involving OTs that are listed by PubMed and Ovid, EMBASE, and Cochrane Library, embracing the period from January 1960 to January 2010, to verify their incidence worldwide. We identified 195 articles, of which 19 articles were selected, considering the location, age, sex, histologic type, and World Health Organization classification. RESULTS: A total of 8544 OTs were found. The results showed a low frequency of malignant OTs in selected works. The most frequent tumor was ameloblastoma (39.6%), followed by odontoma (20.1%) and the newly included keratocystic OT (13.8%). CONCLUSIONS: These OTs are uncommon lesions in world population, and malignant OTs are very rare. The relative frequency of different kinds of OTs, the age, and the sex distribution show a marked geographic variation in incidence of those lesions. This was particularly notable in the ameloblastomas and odontoma, with the incidences being relatively well and weighted showing similar values to an average when compared with previous studies.

Movimentação ortodôntica com mini-implantes: relato de caso clínico / Orthodontic movement with mini-implants: Case report

A ancoragem ortodôntica através de mini-implantes tornou-se uma alternativa ímpar no tratamento de pacientes adultos com más posições dentárias, bem como para edêntulos parciais, em que a ancoragem convencional traria limitações no tratamento. Neste artigo, será relatado um caso clínico de paciente do gênero feminino, classe II, com desvio de linha média superior para a esquerda, próteses fixas dos dentes 24 ao 27 e ausência dos dentes 14 e 15. O tratamento de escolha foi a instalação de mini-implante como ancoragem absoluta para utilização de mola de níquel-titânio para mecânica ortodôntica de distalização. Dessa forma, este artigo tem a finalidade de mostrar a importância da associação e planejamento dos mini-implantes como coadjuvantes para ancoragem no tratamento ortodôntico fixo.

The use of implants as orthodontic anchorage has became an important alternative when treating adult patients with unfavorable tooth position or partially edentulous area when the conventional anchorage would produce limitations in the treatment. The purpose of this paper is to describe a case report of a adult female, with skeletal Class II, an upper dental midline deviation to the left, with fixed bridge from 23 to 26 and the absence of the 14 and the 15. For the current treatment a mini screw was used as absolute anchorage and a niquel titanium closed coil for distalizing mechanics. The objective of this article is to show the importance of mini screws for anchorage associated with fixed appliances.

Cimento de alfa-tricálcio-fosfato na reconstrução de defeitos ósseos em ratos / Alpha-tricalcium phosphate cement in the reconstruction of bone defects in rats

PURPOSE: To evaluate the ability of a mixture of α-TCP and autogenous bone (AB) vs. α-TCP alone and AB alone to promote new bone formation and tissue repair in bone defects. METHODS: Bone defects surgically created in 15 male Wistar rats were divided into four groups: Group I (AB), Group II (α-TCP), Group III (α-TCP+AB assessed by light microscopy), and Group IV (α-TCP+AB assessed by scanning electron microscopy). Bone repair findings were assessed at 30, 60, and 120 days postoperatively. RESULTS: The histological findings obtained in Groups I (p=0.459), II (p=0.368), and III (p=0.459) and at 30 days (p=0.717), 60 days (p=0.717), and 120 days (p=0.779) did not show statistically significant differences. Scanning electron microscopy revealed direct contact between the α-TCP+AB implant and the bone tissue at 120 days. CONCLUSION: The α-TCP implant is effective alternative bone substitutes for the treatment of critical size bone defects.

OBJETIVO: Avaliar a capacidade da mistura de α-TCP e osso autógeno (OA) Vs somente α-TCP e somente OA em promover a neoformação óssea e reparo tecidual em defeitos ósseos. MÉTODOS: Foram criados cirurgicamente defeitos ósseos em 15 ratos Wistar machos, distribuídos em quatro grupos: Grupo I (OA), Grupo II (α-TCP), Grupo III (α-TCP + OA avaliado por microscopia de luz) e Grupo IV (α-TCP + OA avaliado por microscopia eletrônica de varredura). Os resultados da reparação óssea foram avaliados em 30, 60 e 120 dias. RESULTADOS:os achados histológicos obtidos nos grupos I (p = 0,459), II (p = 0,368) e III (p = 0,459) e aos 30 dias (p = 0,717), 60 dias (p = 0,717), e 120 dias (p = 0,779) não apresentaram diferenças estatisticamente significativas. A análise por microscopia eletrônica de varredura revelou contacto direto entre o implante de α-TCP + AO e o tecido ósseo aos 120 dias. CONCLUSÃO: O implante de α-TCP é alternativa eficaz como substitutos ósseos para o tratamento de defeitos ósseos de tamanho crítico.

Cimento de alfa-tricálcio-fosfato na reconstrução de defeitos ósseos em ratos / Alpha-tricalcium phosphate cement in the reconstruction of bone defects in rats

PURPOSE: To evaluate the ability of a mixture of α-TCP and autogenous bone (AB) vs. α-TCP alone and AB alone to promote new bone formation and tissue repair in bone defects. METHODS: Bone defects surgically created in 15 male Wistar rats were divided into four groups: Group I (AB), Group II (α-TCP), Group III (α-TCP+AB assessed by light microscopy), and Group IV (α-TCP+AB assessed by scanning electron microscopy). Bone repair findings were assessed at 30, 60, and 120 days postoperatively. RESULTS: The histological findings obtained in Groups I (p=0.459), II (p=0.368), and III (p=0.459) and at 30 days (p=0.717), 60 days (p=0.717), and 120 days (p=0.779) did not show statistically significant differences. Scanning electron microscopy revealed direct contact between the α-TCP+AB implant and the bone tissue at 120 days. CONCLUSION: The α-TCP implant is effective alternative bone substitutes for the treatment of critical size bone defects.(AU)

OBJETIVO: Avaliar a capacidade da mistura de α-TCP e osso autógeno (OA) Vs somente α-TCP e somente OA em promover a neoformação óssea e reparo tecidual em defeitos ósseos. MÉTODOS: Foram criados cirurgicamente defeitos ósseos em 15 ratos Wistar machos, distribuídos em quatro grupos: Grupo I (OA), Grupo II (α-TCP), Grupo III (α-TCP + OA avaliado por microscopia de luz) e Grupo IV (α-TCP + OA avaliado por microscopia eletrônica de varredura). Os resultados da reparação óssea foram avaliados em 30, 60 e 120 dias. RESULTADOS:os achados histológicos obtidos nos grupos I (p = 0,459), II (p = 0,368) e III (p = 0,459) e aos 30 dias (p = 0,717), 60 dias (p = 0,717), e 120 dias (p = 0,779) não apresentaram diferenças estatisticamente significativas. A análise por microscopia eletrônica de varredura revelou contacto direto entre o implante de α-TCP + AO e o tecido ósseo aos 120 dias. CONCLUSÃO: O implante de α-TCP é alternativa eficaz como substitutos ósseos para o tratamento de defeitos ósseos de tamanho crítico.(AU)

Alpha-tricalcium phosphate cement in the reconstruction of bone defects in rats.

PURPOSE: To evaluate the ability of a mixture of α-TCP and autogenous bone (AB) vs. α-TCP alone and AB alone to promote new bone formation and tissue repair in bone defects. METHODS: Bone defects surgically created in 15 male Wistar rats were divided into four groups: Group I (AB), Group II (α-TCP), Group III (α-TCP+AB assessed by light microscopy), and Group IV (α-TCP+AB assessed by scanning electron microscopy). Bone repair findings were assessed at 30, 60, and 120 days postoperatively. RESULTS: The histological findings obtained in Groups I (p=0.459), II (p=0.368), and III (p=0.459) and at 30 days (p=0.717), 60 days (p=0.717), and 120 days (p=0.779) did not show statistically significant differences. Scanning electron microscopy revealed direct contact between the α-TCP+AB implant and the bone tissue at 120 days. CONCLUSION: The α-TCP implant is effective alternative bone substitutes for the treatment of critical size bone defects.

Análise histológica comparativa entre o reparo de feridas cutâneas tratadas por sutura com fio de náilon e o adesivo octil-2- cianoacrilato em ratos / Comparative histological analysis among repair of skin wounds treated by suture with nylon and the adhesive octyl-2-cyanoacrylate in rats

Introdução: A síntese das feridas cirúrgicas é conceituada como o conjunto de manobras que visam aproximar os tecidos divididos ou separados durante os atos cirúrgicos de incisão ou divulsão, permitindo o seu fechamento de maneira que ocorra um adequado reparo tecidual e, ao mesmo tempo, objetivando a busca da harmonia estética dos tecidos incisados. O objetivo deste trabalho é avaliar histologicamente feridas incisas tratadas com fio Mononylon 4-0 e adesivo octil-2-cianoacrilato. Métodos: Para o seu desenvolvimento, foram utilizados sete ratos da linhagem Wistar, em cujo dorso foram realizadas duas feridas incisas, uma tratada por sutura com Mononylon 4-0 e outra, pelo adesivo octil-2-cianoacrilato. As amostras foram coletadas nos períodos de 24h, 48h, 72h e 7 dias pós-operatórios. Resultados e Conclusão: pode-se observar que o octil-2-cianoacrilato mostrou um reparo tecidual semelhante ao fio de náilon, porém este necessitou de menor tem-po para o fechamento da ferida, com maior facilidade na aproximação dos bordos.

Produção científica da ULBRA: análise do número e do delineamento das pesquisas publicadas nos suplementos da Brazilian Oral Research (SBPqO) / ULBRA scientific production analysis of the number and the design of research published in the Brazilian Oral Research supplements (SBPqO)

A reunião anual da Sociedade Brasileira de Pesquisa Odontológica (SBPqO) é um evento representativo para a divulgação das pesquisas cientificas na área de odontologia realizadas no Brasil. O objetivo do presente trabalho foi realizar o levantamento das publicações realizadas pelo corpo docente e discente do Curso de Odontologia da Universidade Luterana do Brasil/ULBRA (Campus Canoas, Cachoeira do Sul e Torres) nos Suplementos da Brazilian Oral Research, periódico científico oriundo das apresentações dos painéis na SBPqO. Para isso, os resumos publicados foram acessados por meio de consulta on line no site da instituição e catalogados conforme o ano da reunião, o código da pesquisa, os autores (por sobrenome), a categoria do painel e o delineamento do estudo. Os dados foram transferidos para uma tabela a partir da primeira publicação e analisados em relação ao número de publicações/ano e quanto ao delineamento do estudo. O ano de 2006 apresentou o maior número de publicações (50), entretanto a produtividade apresenta-se em declínio nos últimos três anos (2007, 2008 e 2009). O delineamento da maioria das pesquisas no período analisado são laboratoriais (in vitro) e transversais, ou seja, estudos com baixo poder de gerar evidência científica.

The Brazilian Society for Dental Research (SBPqO) is an annual meeting for the publishing of the dentistry scientific research in Brazil. The aim of this study was to search publications by students and professors of School of Dentistry, Lutheran University of Brazil / ULBRA (Canoas, Cachoeira do Sul, Torres) in the Brazilian Oral Supplements Research, a scientific journal dedicated to publication of SBPqO research banners. Published abstracts were accessed by online searching on site of SBPqO and organized according to: year, code research, authors (surname), banner category and the study design. Data were organized in a table from the first publication and analyzed in relation to the frequency of publications per year and study design. In 2006 there was the highest number of publications (50). However, the publications are decreasing on last three years (2007, 2008 e 2009). The design of most publications at period was in vitro and cross-sectional. These studies have low capacity to generate scientific evidence.