ABSTRACT
Comparative estimation of the local treatment results for purulent-inflammatory diseases of soft tissues, using standard methods and composition, owing sorption and antimicrobial properties and basing on a nanodispersedsilica, was conducted. The composition application in complex of treatment have promoted more rapid clearance from necrotized tissues and microorganisms, rapid appearance of granulations, the intoxication severity reduction, the phase I of the wound process duration shortening, what have permitted to put secondary sutures on the wound on the 6 7th postoperative day, and total duration of the patients' stationary treatment have reduced by 3.7 days.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Escherichia coli Infections/drug therapy , Nanocomposites/chemistry , Soft Tissue Infections/drug therapy , Staphylococcal Infections/drug therapy , Suppuration/drug therapy , Wound Infection/drug therapy , Administration, Topical , Escherichia coli/drug effects , Escherichia coli/growth & development , Escherichia coli/pathogenicity , Escherichia coli Infections/microbiology , Escherichia coli Infections/pathology , Escherichia coli Infections/surgery , Humans , Nanocomposites/administration & dosage , Silicon Dioxide/chemistry , Soft Tissue Infections/microbiology , Soft Tissue Infections/pathology , Soft Tissue Infections/surgery , Sorption Detoxification/methods , Staphylococcal Infections/microbiology , Staphylococcal Infections/pathology , Staphylococcal Infections/surgery , Staphylococcus aureus/drug effects , Staphylococcus aureus/growth & development , Staphylococcus aureus/pathogenicity , Staphylococcus epidermidis/drug effects , Staphylococcus epidermidis/growth & development , Staphylococcus epidermidis/pathogenicity , Suppuration/microbiology , Suppuration/pathology , Suppuration/surgery , Treatment Outcome , Wound Healing/drug effects , Wound Infection/microbiology , Wound Infection/pathology , Wound Infection/surgeryABSTRACT
The analysis of intestinal differentiation transcription factor CDX2 in the gastric mucosa biopsies has been carried out. It was established that CDX2 by itself promoter activation pathway can obtain intestinal phenotype for gastric mucosa cells. The loss of CDX2 expression in the nuclei of metaplastic epithelium may serve as a predictor of gastric mucosa malignization.
