Clinical Peri-Implant Parameters and Marginal Bone Loss for Early Mandibular Implant Overdentures: A Follow-Up of 60 Months.

Background and Objectives: Despite the identified benefits of early implant loading, studies have questioned its advantages compared to delayed loading in edentulous patients. This study aimed to evaluate clinical peri-implant parameters and marginal bone loss around early placed and loaded mandibular implant overdentures with a 60-month follow-up. Materials and Methods: In this prospective cohort study, 43 patients were enrolled to receive 86 early loading sub-crestal dental implants through prosthetic guides. Implant overdentures were supported by two isolated implant locator attachments between two mental foramens. Clinical peri-implant parameters, including plaque index (PI), bleeding index (BI), peri-implant pocket depth (PIPD), and marginal bone loss (MBL) were evaluated using standardized techniques at 1, 12, 24, 36, 48, and 60 months follow-up. At 60 months, complications associated with implant overdentures (IOD's) were noted. The mean comparison of peri-implant clinical parameters was performed through ANOVA test. A p-value of ≤0.05 was taken as significant. Results: Out of the total 43 enrolled patients, 8 patients were lost during follow-up; as a result, 35 patients completed the 5 years follow-up. The mean values of PI, BI, and PIPD increased with no statistical difference (p > 0.05). For marginal bone loss, an increase in the mean values was noted at different time intervals with statistical differences (p < 0.001). The most common complications noted were loosening of the abutment, occlusal adjustment, retentive locator loosening and replacement, and relining of the denture. Conclusions: Early placement of IODs failed to prevent bone loss over time and was associated with complications, predominantly consisting of abutment loosening, occlusal adjustments, broken retentive locator components, relining, and rebasing.

The Surface Roughness of Contemporary Indirect CAD/CAM Restorative Materials That Are Glazed and Chair-Side-Finished/Polished.

The surface roughness (Ra) of indirect computer-aided design/computer-aided manufacturing (CAD/CAM)-fabricated dental restorations is crucial for their long-term durability. This study intended to evaluate the Ra of five different types of contemporary indirect CAD/CAM restorative materials with varying compositions that were glazed and finished/polished. A total of 75 specimens, disc-shaped (10 mm × 2 mm), were obtained from five materials (n = 15) (Tetric CAD, IPS e.max CAD, IPS e.max ZirCAD, CELTRA Duo, and Vita Enamic) and fabricated by CAD/CAM. One of the two surfaces for each specimen was subjected to glazing, while the other surface was subjected to finishing/polishing. The Ra of the two surfaces in micrometers (µm) was evaluated using a Profilometer, while the surface topography was examined using a scanning electron microscope. Using SPSS, the Kruskal-Wallis, post hoc Conover, and Mann-Whitney tests were used to statistically evaluate the data. A comparison of the Ra for the finished/polished surfaces of the five test materials showed significant differences (p < 0.0001). Among the finished/polished surfaces, the mean rank values of Vita Enamic were significantly higher than the other four test materials (p < 0.0001). A comparison of the Ra of glazed surfaces among the five study materials revealed significant differences (p < 0.0001). The Ra for the IPS e.max ZirCAD material was significantly higher than the rest of the four materials (p < 0.001). A comparison of the Ra for two types of surface conditioning within each of the five test materials showed a significant difference (p < 0.05). Only for IPS e.max ZirCAD was the Ra of the glazed surface significantly higher than the finished/polished surface (p < 0.0001). Significant variations in the surface roughness (Ra) were exhibited between the finished/polished and glazed surfaces of the five test materials. Hybrid ceramics showed the highest Ra values for the finished/polished surfaces, and zirconia exhibited the highest Ra values among the glazed surfaces among the tested materials. The Ra values of either finished/polished or glazed surfaces of the test materials were within the clinically acceptable range (0.2-0.5 µm), except for the glazed surface of the zirconia ceramics (0.84 µm).

A novel digital workflow for fabricating artificial periodontal ligament using three-dimensional printing flexible resin: A dental technique.

The fabrication of periodontal ligament (PDL) models for in vitro dental studies has seen a wide range of techniques and materials being utilized. This paper introduces a novel dental technique that employs a digital workflow for the fabrication of artificial PDL using three-dimensional printing of flexible resin. This innovative approach offers several advantages, including enhanced accuracy and realism in simulating PDL. The digital workflow facilitates a streamlined fabrication process, ensuring efficiency and precision. By presenting this novel technique, this digital approach contributes to the advancement of in vitro dental research, providing researchers with a reliable and realistic model for studying various dental phenomena.

Evaluation of Peri-Implant Parameters and Functional Outcome of Immediately Placed and Loaded Mandibular Overdentures: A 5-year Follow-up Study.

PURPOSE: To evaluate the peri-implant parameters of immediately placed and loaded mandibular overdentures over a 5-year follow-up period. MATERIALS AND METHODS: All subjects who had been advised and planned for two-implant mandibular overdenture treatment were included in this study. The peri-implant parameters -including plaque index (PI), bleeding index (BI) and peri-implant pocket depth (PIPD) as well as marginal bone loss (MBL) - were assessed. In addition, prosthodontic parameters including abutment-, implant- and denture-related complications were assessed. Patients were evaluated at follow-up visits, scheduled at 1, 12, 24, 36, 48, and 60 months. The data distribution was analysed with the Shapiro-Wilk test. Data within follow-up categories were compared using ANOVA and the Tukey-Kramer test. A p-value < 0.05 was considered statistically significant. RESULTS: Among the 32 participants, 19 were males and 13 were females, with a mean age of 60.5 ± 7.33. The mean plaque index (PI), bleeding index (BI) and peri-implant pocket depth (PIPD) varied over time. However, no statistically significant difference was observed in the plaque index, bleeding index and peri-implant pocket depth over time (p > 0.05). The mean value at baseline was found to be -0.9 ± 0.3. The values increased over time, with the highest value observed at 60 months 2.6 ± 0.7, which was statistically significant (p < 0.001). CONCLUSION: Immediately placed and loaded mandibular implant overdentures using two un-splinted implants with locator attachments showed acceptable PI, BI and PIPD at the 5-year follow-up. Statistically significantly greater marginal bone loss was observed from baseline to follow-up, but it was within acceptable limits. A moderate number of restorative and abutment complications were observed during the follow-up of IODs.

Biomechanical behavior of all-ceramic endocrowns fabricated using CAD/CAM: A systematic review.

PURPOSE: This study performed a systematic review to assess the biomechanical behavior of all-ceramic endowcrowns fabricated using computer-aided design and computer-aided manufacturing (CAD/CAM) for the restoration of endodontically treated teeth. STUDY SELECTION: Three electronic databases (PubMed, Web of Science, and Scopus) were searched by operators specializing in health sciences databases searches to answer the following focused question based on the Population, Intervention, Comparison, Outcome (PICO) format: "Whether all-ceramic CAD/CAM endocrowns (Intervention) used to restore human endodontically treated teeth (Population) exhibit superior fracture resistance (Outcome) compared to non-CAD/CAM all-ceramic or non-ceramic endocrowns (Comparison)." The methodological quality assessment was performed using previously conducted systematic reviews of in vitro studies. The outcomes were expressed as the mean ± the standard deviation (SD). RESULTS: Seventeen in vitro studies were included. The materials used in these studies were lithium disilicate glass-ceramic, polymer-infiltrated ceramic, zirconia-reinforced lithium silicate glass-ceramic, resin/hybrid nanoceramics, zirconia-reinforced lithium silicate ceramics, and feldspathic ceramic. The fracture resistance of endocrowns using different ceramics varied as follows: (i) IPS e.max CAD (2863.62 ± 51.47 N), (ii) Vita Enamic (1952 ± 378 N), (iii) Vita Suprinity (1859 ± 588 N), (iv) Cerasmart (1981 ± 169.5 N), (v) LAVA Ultimate (2484 ± 464 N), (vi) Celtra Duo (1618.30 ± 585.00 N), and (vii) Cerec Blocs (236.29 ± 32.12 N). CONCLUSIONS: CAD/CAM all-ceramic endocrowns can withstand occlusal forces in the posterior region. All-ceramic endocrowns improve the fracture strength of endodontically treated teeth. Lithium disilicate crowns were commonly and successfully used in the included studies. More in vitro investigations that implement uniformity in material and measurement approaches are required to strengthen the evidence currently available in the literature regarding the durability of all-ceramic endocrowns.

Complications Associated with Metal Resin Fixed Complete Dentures Based on Implant Distribution.

PURPOSE: To compare prevalence and type of complications associated with metal resin fixed complete dentures based on implant distribution. MATERIALS AND METHODS: This retrospective study included data collected for a period of 12 years for patients treated with maxillary and mandibular implant-supported fixed complete dentures at Loma Linda University School of Dentistry. In total, 223 patient's charts were reviewed which included 100 maxillary and 123 mandibular fixed complete dentures. Implant distribution and prevalence of complications associated with each implant-supported fixed complete denture were documented. Tooth delamination, the most common complication associated with fixed complete dentures, was compared between 2 implant distribution groups in each arch. Covariates including age, sex, opposing arch, cantilever occluding units, and number of implants were evaluated to determine their association with tooth delamination. Data and hypotheses were statistically analyzed using descriptive statistics along with logistic regression model. All tests of hypotheses were considered statistically significant at an alpha level of 0.05. RESULTS: In the maxillary arch, some effect of the prevalence of tooth delamination was seen for the group that had implants placed posterior to canine eminence but it was not statistically significant. Denture tooth delamination had the highest prevalence among complications irrespective of implant distribution. Significant denture tooth delamination was seen for patients with opposing fixed complete dentures in comparison to patients with removable opposing arch prostheses. CONCLUSIONS: Implant distribution is not a significant factor related to metal resin fixed complete dentures. Opposing fixed complete dentures have a significantly higher association with denture tooth delamination.

Push-Out Bond Strength of Endodontic Posts Cemented to Extracted Teeth: An In-Vitro Evaluation.

(1) Background: An ideal bond strength between endodontic posts and root canal dentin is essential for optimal retention and good prognosis. This study aimed to evaluate the push-out bond strength (PBS) of prefabricated fiber and metal posts, luted with resin cement to natural dentin. (2) Methods: Extracted premolars with similar root dimensions were assigned into two groups of 30 each for the metal and fiber posts. Teeth were mounted in acrylic blocks exposing 2 mm of the coronal root. Teeth were subjected to endodontic treatment and post-space preparations. Two groups were further subdivided into three sub-groups (n = 10) according to the size of the posts (# 4, 5 and 6). Posts were cemented with resin cement. Specimens were sectioned into 4 mm slices and subjected to the PBS test. (3) Results: The mean PBS was similar for the metal and fiber posts bonded with resin cement, showing a statistically significant result. An increase in post size increased the bond strength initially, but a further increase in size did not show any marked difference. A total of 71.66% of tested specimens failed with the adhesive failure mode. (4) Conclusions: Metal posts showed slightly higher retention compared to the fiber posts, although the p-value was similar for both types. An increase in the size of posts showed increased retention. The most common mode of failure was adhesive failure between cement and dentin.

Scanning accuracy with splinted and unsplinted implant scan bodies for the edentulous arch at implant level: an in vitro study.

Accuracy of completely edentulous arch scanning with implant scan bodies has not been completely validated for intraoral scanners. For desktop laboratory scanners validations were found in the literature. The aim of this in vitro study was to compare the dimensional accuracy of scanning with splinted and unsplinted scan bodies on a completely edentulous maxillary arch with 6 implants. A maxillary edentulous master cast with 6 implants was used as control for all implant level impressions. 6 implants were digitally planned and placed at different angulation of 0, 0  17° and 30°. A contact coordinate measuring machine (CMM) was used to generate baseline linear measurements of the master cast. Four test groups included: 2 intraoral scanners Trios (3shape, Copenhagen, Denmark) and True Definition (3M ESPE, St Paul, MN), one industrial scanner Atos (Core optical 3D scanner) and one conventional impression group scanned with laboratory scanner Dental Wings 7 Series. Each scan recording was made with splinted and unsplinted scan bodies. Digital datasets of all measurements were compared with the CMM baseline values using PolyWorks® InnovMetric Software in order to assess the linear and angular deviations and determine the accuracy of complete arch digital impression. Factorial ANOVA showed significant effect with splinting, scanner type, inter-implant distance and implant angulation for linear deviations. Splinted scan bodies revealed elevated linear and angular deviation values for all scanners with significantly highest deviations for True Definition scanner. Significant correlation was found between inter-implant distance and linear deviation (r =0.45, P =<0.001) with increased linear deviations among all scanners, regardless of splinting. ( P <0.05). Significant effect on accuracy was seen for angular deviation with splinting, scanner type and implant angulation; significant difference was found between 0° and 30° implant angulation ( P =0.035) with more deviation with 30° implant angulation. The accuracy of the complete arch implant digital impression using splinted scan bodies was significantly reduced for measurements that crossed the arch midline. The digital impression technique using a broad splint design to connect scan bodies was not found to improve the scan accuracy for intraoral scanners.

Influence of Conventional Polymer, Hybrid Polymer and Zinc Phosphate Luting Agents on the Bond Strength of Customized Zirconia Post in Premolars-An In-Vitro Evaluation.

The aim was to identify the influence of conventional polymeric resin based cement (RC), hybrid polymer modified glass ionomer (RMGIC) and Zinc phosphate cement (ZPC) on the pull out strength of the customized zirconia post in premolars. Access cavity and root canals were performed in sixty premolar teeth with the standardized crown down technique (ProTaper Universal, Dentsply). Post space impressions were scanned, and the pre-sintered Zenostar Zr Translucent blanks (Weiland Dental, Pforzheim) were milled with the Opera-system to form the post. All prepared specimens were divided equally in three groups based on the cement type employed for luting as follows: group A: ZPC; group B (GC Fuji PLUS Capsule): RMGIC; group C (and RC (3M RelyX ARC). Ten specimens in each group were thermocycled (TC) at 5 and 55 °C in distilled water baths (40,000 cycles). Pull out bond strength was assessed using a universal testing machine at 0.5 mm/min. The means and standard deviations were compared using ANOVA and Tukey Kramer multiple comparisons tests. A significant difference among the cement groups as well as between TC and non-thermocycled (NTC) groups (p < 0.05) was observed. The highest tensile stress was demonstrated among group C (Resin, 69.89 ± 4.81 (NTC), 64.06 ± 4.36 (TC)) with the least in group A, (zinc phosphate, 43.66 ± 5.02 (NTC), 37.70 ± 5.10 (TC)) for both groups. Group A presented with 100% adhesive bond failures, followed by 80% in group C and 70% in group B, respectively. A similar outcome was observed in the TC group for the cement; however, unlike the NTC group, the TC group showed more cohesive failures compared to the NTC mixed failure. Dual cure polymer based cement demonstrated higher bond strength and efficient adhesive bonding of the customized Zr post with root dentine compared to zinc phosphate (non-polymeric) and RMGIC (hybrid polymer). Thermocycling compromised Zr post adhesive bonding to root dentin.

Disinfection efficacy and fracture strength of PMMA denture-based polymer with chlorhexidine, PDT utilizing Rose Bengal and hematoporphyrin, and Er, Cr: YSGG laser.

OBJECTIVE: The study aimed to assess and compare disinfection efficacy and fracture strength of PMMA based DBPs using chlorhexidine (CHX), PDT utilizing Rose Bengal (RB) and hematoporphyrin HPD, and Er,Cr:YSGG laser (ECL) induced antimicrobial action against in-vitro biofilms colonized with C.albicans, S.aureus, S. mutans, and E. coli. MATERIAL AND METHODS: American Type Culture Collection (ATCC) of C.albicans, S.aureus, S. mutans and E. coli were cultured. Forty-eight PMMA-based denture base plates (DBPs) were prepared by heat-cure acrylic resin and contaminated by in-vitro biofilm under-stimulated in-vitro conditions. DBPs were treated with group1; ECL group 2; RB 5µm, group 3; HPD 500 mg/L and group 4; 0.12% CHX (controls) respectively, for the disinfection of biofilms. All photosensitizers (PS) were activated by LED at a different wavelength. Each contaminated DBP was sprayed on all its surfaces with the aforementioned photosensitizers and CHX. One-way analysis of variance (ANOVA) was used to test the efficacy of disinfection and fracture load testing. Tukey multiple comparison tests were performed to compare means of CFU/mL (log10) for exposed E. coli, C. albicans, S aureus, and S. mutans. RESULTS: Specimens in group 1 disinfected with erbium laser, group 3 disinfected with HPD, and group 4 sterilized with chemical disinfection were effective in decreasing bacterial load CFU/mL (log10) against C.albicans, S. aureus, S.mutans, and E. Coli (p>0.05). Intergroup comparison demonstrated ECL, CHX and HPD demonstrated a comparable reduction against C.albicans and S.aureus (p>0.05). Similarly, S.mutans and E.coli were sensitive against all experimental groups (p>0.05). no significant difference in fractural load analysis among the different investigated groups was noted (p>0.05). CONCLUSION: ECL and HPD photosensitizer revealed a significant reduction in CFU/ml of exposed viable colonies of C.albicans, S.aureus, S. mutans, and E. coli comparable to 0.12% CHX mediated disinfection of PMMA-based DBPs. Irrespective of the type of disinfection no influence of disinfection was noted on the fracture load of PMMA DBPs.

Comparison of adhesive bond strength among fiber reinforced post and core with different cementation techniques: In vitro study.

AIM: To investigate push-out bond strength (PBS) of fiber post to radicular dentin after using different cementation techniques. MATERIAL AND METHODS: Sixty single-rooted premolars were disinfected and cleaned by mechanical instrumentation. S1, S2, and SX were used for canal shaping and finishing of the canal was carried out using F1 and F2. This was followed by constant irrigation and smear layer removal using 17%EDTA. The canal was dried filled with gutta-percha and canal space was prepared using a peso reamer. Based on cementation techniques, samples were randomly allocated into six groups. Group 1: One-step Monoblock MC; Group 2: One-step, Monoblock MC-NA (no adhesive) GFP; Group 3: One-step, RX-MC-Monoblock; Group 4: Two-step, RX-MC; Group 5: Two-step, RX-FZ; and Group 6: Two-step RX-FZ-custom post. All specimens were mounted in polyvinyl pipes using acrylic resin up to cement enamel junction. All specimens were mounted in a universal testing machine subjected to push-out forces at a speed of 0.5 mm/min. Five samples from each group were sputter-coated with 6 nm gold thickness for 300 s at 250 mA. The coated specimens were assessed under the scanning electron microscope (SEM). Analysis of variance (ANOVA) and Tukey Kramer multiple comparisons tests were performed to compare means among groups maintaining the level of significance at (p < 0.001). RESULTS: The highest PBS was displayed in RX-MC-Monoblock (199.020 ± 21.432 MPa). Whereas, lowest PBS was found in Monoblock MC-NA (no adhesive)-GFP (76.440 ± 9.468 MPa). Among one-step groups, RX-MC Monoblock exhibited the highest PBS (199.020 ± 21.432 MPa) comparable to one-step Monoblock MC (134.28 ± 19.37 MPa) (p > 0.05). Similarly, among two-steps groups, two-step RX-MC demonstrated significantly higher PBS values than two-step RX-FZ (143.340 ± 23.68 MPa) and RX-FZ-custom post (86.90 ± 7.41 MPa) (p < 0.05). CONCLUSION: One-step RX-MC-Monoblock technique using self-adhesive cement and core foundation composite resin material multicore flow when cured simultaneously exhibited the highest bond integrity of post retention compared to other cementation technique.

Influence of milling systems and marginal configurations on the fit of yttrium stabilized tetragonal zirconia polycrystals (Y-TZP)' copings.

OBJECTIVE: The aim of this study was to evaluate marginal fit of yttrium tetragonal zirconia polycrystals (Y-TZP)' copings with different finish line designs fabricated with various digital scanners and milling systems. METHODS: Three model plastic teeth were prepared with three finish line designs: Design-1, continuous chamfer; Design-2, chamfer with shallow depression; Design-3, chamfer with deep depression. The "master models" were replicated using elastomeric polyvinyl siloxane impression material and poured in type IV stone generating 90 dies, 30 dies for each design. Dies were scanned and copings were milled utilizing three digital scanners and computer-aided design/computer-aided manufacturing (CAD/CAM) systems: System-1, InEos Red Scan (Sirona Dental Systems, Germany), Vitablocks® Mark II (VITA, Germany) copings milled by Cerec® inLab (Sirona Dental Systems, Germany); System-2, Cerec® AC Connect with BlueCam (Sirona Dental Systems, Germany), Vitablocks® Mark II (VITA, Germany) copings milled by Cerec® inLab (Sirona Dental Systems, Germany); and System-3, NobleProcera™ Optical Scanner (NobleBiocare™), procera zirconia coping milled by a Noble Procera™ milling machine (NobleBiocare™). Copings were seated on their respective "master models" and secured with uniform force. Eight measurements per coping were performed at pre-established points, with a metallurgical microscope (Zeiss, Germany) connected to a high precision digital video-micrometer (Javelin JV6000, California, USA) at 200 × magnification. RESULTS: The tested systems demonstrated marginal gaps ranging from 12.4 to 26.6 µm. Results for marginal fit of milled copings fabricated using three systems with different finish line designs differed significantly (p < 0.05). Procera zirconia copings scanned and milled with NobleProcera™ exhibited significantly lower marginal gaps compared to other specimen groups. However, InEos Red Scan/Vitablocks® Mark II/Cerec® inLab showed maximum marginal gaps among the study specimens. CONCLUSIONS: CAD-CAM manufactured Y-TZP' copings exhibited marginal gaps ranging from 12.49 to 26.6 µm. The CAD-CAM fabrication system was a significant factor influencing the marginal misfit of Y-TZP' copings. Margin design exhibited system dependent influence on the marginal misfit. Marginal misfit observed for all systems were within clinically acceptable parameters.

Efficacy of Scaling and Root Planing with Photobiomodulation for Treating Periodontitis in Gutka Chewers: A Randomized Controlled Trial.

Objective: To explore the influence of photobiomodulation (PBMT) as an adjuvant to scaling and root planing (SRP) for treating periodontitis among gutka chewers. Materials and methods: Self-reported smokeless-tobacco (gutka) users were enrolled; and underwent SRP with (test group) and without (control group) PBMT. Full-mouth plaque index (P-I), bleeding upon probing (BUP), probing depth (P-D) clinical attachment loss (CAL), marginal bone loss (MBL) (on mesial and distal surfaces of the teeth), and number of missing teeth were recorded before treatment and at 3 and 6 months. Group comparisons were performed and p < 0.05 was referred significant. Results: In the control group, P-I (p < 0.013), BUP (p < 0.001), and P-D (p < 0.012) were high at baseline compared with 3 months follow-up. P-I, BUP, and P-D were higher in the test group, at baseline in comparison with the 3-month (p < 0.001) and 6-month (p < 0.01) follow-up. At 3 and 6 months, scores of P-I, BUP, and P-D were high in the control compared with the test group. No difference in CAL, and mesial and distal MBL was found among patients of both groups at 3 and 6 months. Conclusions: Among gutka chewers, SRP with PBMT is more efficient than SRP alone in the management of periodontitis.

Clinical peri-implant health and biological bone marker levels in tobacco users treated with photodynamic therapy.

BACKGROUND: What impact does tobacco smoking have on photodynamic therapy (PDT) outcome is still unknown. The aim of the present clinical trial was to evaluate the clinical, radiographic, and biological bone markers after provision of PDT in cigarette, e-cigarette, and never-smokers with peri-implantitis (PI) at 6 months post treatment. MATERIALS AND METHODS: Twenty-five healthy patients with PI were divided into three groups: Group I: cigarette smokers; Group II: e-cigarettes users; Group III: never-smokers. Full-mouth mechanical debridement with adjunctive methylene blue-mediated PDT was performed. Clinical recordings included peri-implant plaque index (Pi), bleeding on probing (BOP) and probing depth (PD). Peri-implant sulcular fluid was collected for the assessment of biological bone biomarkers including receptor activator of nuclear factor-ligand (RANK-L) and osteoprotegrin (OPG). All assessments were performed at baseline, 3 months and 6 months. P-value of <0.05 was considered significant. RESULTS: BOP in Group II and III significantly reduced at 3 months (p < 0.05). Group I showed significant reduction only at 6 months (p < 0.05). Mean PD showed no statistically significant difference between the groups at any time-point. Inter-group comparison showed Group III demonstrating statistically significantly reduced mean RANK-L levels at both 3 and 6 months (p < 0.05). A slight increase in the OPG levels were observed at 3 months and followed by a slight decrease at 6 months for all the study groups when compared with baseline values, however, these values did not show statistical significance (p > 0.05). CONCLUSION: Adjunctive PDT helped in reducing the clinical peri-implant inflammation. However, no significant change was observed for biological bone biomarkers among tobacco smokers.

Influence of different photosensitizers on push-out bond strength of fiber post to radicular dentin.

BACKGROUND: To evaluate the effect of different photosensitizer on extrusion bond strength of glass fiber post to radicular dentin. MATERIAL AND METHODS: Forty maxillary and mandibular central incisors were disinfected and decoronated. Mechanical instrumentation of canal was performed using protaper NiTi. Shaping and cleaning of canal comprised of S1, S2, SX with finishing files F1 and F2, followed by continuous irrigation. Canals were dried and obturated with gutta percha. Peso reamers were used to prepare post space. Based on the photosensitizers (PS) used, the samples were divided into three groups (n = 10). Group 1: treated with methylene blue photosensitizer (MBP) at 50 mg/l, Group 2: Curcumin photosensitizer (CP) at 500 mg/l, Group 3: canal space was filled with Toluidine blue photosensitizer (TB) at 100 mg/l. All photosensitizers were activated using different lasers. The samples in group 4 (control) were irrigated using 5.25% sodium hypochlorite (NaOCl) + 17% ethylenediamine tetra acetic acid (EDTA). Posts were cemented and teeth were sectioned into coronal, middle and apical sections. All sections were placed in universal testing machine to evaluate extrusion bond strength in megapascal (MPa). Fracture pattern analysis of samples were seen under stereomicroscope at 50x magnification and categorized into adhesive, cohesive and admixed. Assessment of extrusion bond strength was performed by one-way analysis of variance (ANOVA) and Tukey multiple comparison test (p = 0.05). RESULTS: The highest bond strength was achieved in group 2, including samples treated with curcumin photosensitizer (CP) at all three root levels; cervical (9.01 ±â€¯1.62 MPa), middle (7.95 ±â€¯0.75 MPa) and apical (5.81 ±â€¯0.15 MPa). Whereas, the lowest extrusion bond strength was observed in group 4 (canal irrigated with conventional 5.25% NaOCl +17% EDTA) at coronal (6.10 ±â€¯1.77 MPa), middle (5.11 ±â€¯0.75 MPa) and apical one-thirds (3.65 ±â€¯0.14 MPa). Intra group comparison revealed decrease in extrusion bond strength from coronal to apical direction. Moreover, both group 2 and group 3 showed statistically significant difference to samples in control group and group 1. (p < 0.05). CONCLUSION: TB and CP at concentration of 100 mg/l and 500 mg/l has the potential to be used as an alternate to conventional cleaning regime. TB and CP at this concentration when activated with PDT is likely to improve extrusion bond values.

Clinical and immunological peri-implant parameters among cigarette and electronic smoking patients treated with photochemotherapy: A randomized controlled clinical trial.

BACKGROUND: Although studies have been done that evaluated the effect of photodynamic therapy (PDT) in cigarette smokers and vapers, however, literature on the impact of these types of smoking on peri-implant parameters lack. The present clinical trial assessed the effectiveness of PDT as an adjunctive therapeutic modality in the treatment of peri-implant mucositis (p-iM) in individuals vaping e-cigs and cigarette smokers. METHODS: Individuals with p-iM were divided into three groups. (a) Group 1: Cigarette smokers with p-iM (b) Group 2: Vapers (e-cigarette smokers) with p-iM, (c) Group 3: Non-smokers with p-iM. Plaque index (PI), bleeding on probing (BOP) and probing depth (PD) were calculated. Pro-inflammatory biomarkers including matrix metalloproteinase (MMP)-8 and tumor necrosis factor-alpha (TNF-α) were quantified using enzyme linked immunosorbent assay. All assessments were performed at baseline (before treatment) and 12 weeks post treatment. Full mouth disinfection (FMD) was done with the ultrasonic scaler and copious irrigation. The photodynamic therapy (PDT) was done with a diode laser (wavelength: 670 nm, power: 150 mW, density: 1.1 W/cm2). Methylene blue photosensitizer (0.005% concentration) was incorporated inside the periimplant pockets (10 seconds at a depth of 3 mm), and the pockets were irradiated a flexible tip for one minute on the buccal and lingual surfaces. The session of PDT was performed only once at baseline. RESULTS: Twenty-five cigarette-smokers (Group 1), 21 electronic cigarette smokers (Group 2) and 25 never-smokers (Group 3) participated in the study. The mean age of the selected participants in groups 1, 2 and 3 was 29.5, 27.8, and 30.2 years, respectively. Statistically significant reduction in PI and PD parameters was observed on baseline and at 12 weeks in all groups. BOP significantly increased in group 1 and 2 at 12 weeks. A statistically significant reduction from baseline to 12 weeks was reported in the biomarker levels for all the study groups. CONCLUSION: PDT with adjunctive mechanical debridement reduced the plaque index and probing depth, while increased bleeding on probing, in addition to reducing pro-inflammatory biomarkers in tobacco smokers.

Assessment of advanced glycation end products in the peri-implant sulcular fluid among moderate cigarette-smokers and nonsmokers with peri-implantitis.

BACKGROUND: It is hypothesized that the levels of advanced glycation end products (AGEs) are higher in the peri-implant sulcular fluid (PISF) of cigarette-smokers than nonsmokers with peri-implantitis. PURPOSE: The purpose was to compare the levels of AGEs in the PISF among moderate cigarette-smokers and nonsmokers with peri-implantitis. MATERIALS AND METHODS: Cigarette-smokers and nonsmokers with peri-implantitis and nonsmokers without peri-implantitis were included. A questionnaire was used to gather information related to smoking habit, duration of implants in function and demographic traits. In all groups, peri-implant plaque index (PI), gingival index (GI), crestal bone loss (CBL) and probing depth (PD). The PISF was collected and levels of AGEs were measured. Group comparisons were performed and P < .01 was nominated as pointer of statistical significance. RESULTS: Fourteen smokers with peri-implantitis (12 males and 2 females), 15 nonsmokers with peri-implantitis (14 males and 1 female) and 15 nonsmokers without peri-implantitis (13 males and 2 females) were included. Smokers with peri-implantitis had a smoking history of 22.7 ± 0.3 pack years. The mesial and distal CBL, PI, and PD were significantly higher in smokers with peri-implantitis than nonsmokers with (P < .01) and without peri-implantitis (P < .01). The GI was significantly higher in smokers (P < .01) and nonsmokers with peri-implantitis (P < .01) compared with nonsmokers without peri-implantitis. The levels of AGEs were significantly higher among smokers with peri-implantitis (552.8 ± 87.2 pg/mL) (P < .01) compared with nonsmokers with (141.6 ± 64.9 pg/mL) and without (88.1 ± 27.3 pg/mL) peri-implantitis. The levels of AGEs were significantly higher among nonsmokers with (141.6 ± 64.9 pg/mL) (P < .01) than without (88.1 ± 27.3 pg/mL) peri-implantitis. CONCLUSION: The levels of AGEs expressed in the PISF are higher among moderate cigarette-smokers than nonsmokers with peri-implantitis.

An in vitro investigation comparing methods of minimizing excess luting agent for cement-retained implant-supported fixed partial dentures.

STATEMENT OF PROBLEM: The use of cement-retained implant-supported prostheses is a well-established treatment option. Techniques have been proposed to reduce the amount of residual excess cement (REC) around cement-retained single-implant restorations. However, studies evaluating the effectiveness of such techniques related to cement-retained implant-supported fixed partial dentures (CRISFPDs) are lacking. PURPOSE: The purpose of this in vitro study was to evaluate the effectiveness of various cement application techniques for CRISFPDs. MATERIAL AND METHODS: Two implant analogs were placed in the lateral incisor sites in a maxillary, 3D printed cast with 4 missing incisors. Twenty standardized, removable, printed soft-tissue replicas, 40 milled titanium custom abutments, and 20 milled zirconia CRISFPDs were fabricated. Two cement application techniques, the brush on technique (BOT), and the polyvinyl siloxane index (PI) technique were compared. Two cementation techniques, without bib (control) (n=10) and with a polytetrafluoroethylene (PTFE) bib (test) (n=10), were used. A premeasured amount of interim cement was used to cement the CRISFPDs. The CRISFPDs were retrieved after cementation, and standardized photographs of 4 quadrants of each abutment-CRISFPD assembly were made by using a software program that is used to calculate the ratio between the area covered with REC and the total specimen area. The extension of the REC on both the abutment and soft-tissue replica was measured at sites before and after cleaning the REC. A generalized linear mixed-model procedure was used for statistical analysis (α=.05). RESULTS: For cement application, the polyvinyl siloxane (PVS) index technique had significantly less REC than the brush on technique (P<.05). The use of a PTFE bib led to significantly less REC than when no bib was used (P<.05). CONCLUSIONS: The use of the PVS index technique along with a PTFE bib was effective in reducing REC for CRISFPDs.

Effect of Intraoral Mechanical Cleaning Techniques on Bond Strength of Cast Crowns to Metal Cores.

PURPOSE: To evaluate the effect of cleaning of metal cores from provisional cement, using an intraoral airborne-particle abrasion method, on the bond strength of permanent resin cement with cast crowns to cores. MATERIALS AND METHODS: Thirty stainless steel models of a standard complete crown tooth preparation were fabricated. Thirty Type III gold crowns were fabricated. Each cast crown corresponded to one stainless steel crown preparation model. All crowns were cemented with noneugenol zinc oxide cement and stored for 7 days at 37°C. All crowns were debonded, and the cement was cleaned with airborne-particle abrasion using 50 µm aluminum oxide at 4.1 bar (0.41 MPa) followed by ultrasonic cleaning. Based on the mechanical cleaning technique of the remaining provisional cement on surfaces of cast cores, specimens were equally divided into 3 groups: hand cleaning (HC) with a dental excavator, hand cleaning followed by polishing using a brush and pumice (BP), and hand cleaning followed by intraoral airborne-particle abrasion (APA). All crowns were then cemented to their corresponding cores using universal resin cement. All crowns were stored for 7 days at 37°C. An Instron universal testing machine was used to record the bond strength of crowns. RESULTS: Airborne-particle abrasion method for intraoral mechanical cleaning revealed a statistically significantly higher bond strength compared to the other two methods. CONCLUSIONS: When comparing the three methods of provisional cement cleaning from metal cores, airborne-particle abrasion resulted in the highest bond strength for cast crowns.

Selective implant scan body modification to restore severely tilted adjacent implants: A completely digital workflow.

The advancements in computer-aided design and computer-aided manufacturing (CAD-CAM) serve to facilitate the management of clinical challenges in restorative dentistry. This technique article describes the fabrication of implant-supported restorations by using a completely digital workflow to manage a patient with severely tilted implants.