[The assessment of myocardial perfusion with thallium-201 in patients with a complete left His bundle-branch block]. / Evaluación de perfusión miocárdica con talio-201 en pacientes con bloqueo completo de rama izquierda del haz de His.

Thallium-201 myocardial scintigraphy was used to evaluate coronary perfusion in 20 patients with left bundle branch block suspected of having coronary artery disease. Contemporary coronary arteriography was performed in 9 of these patients. Sensitivity and specificity of the method was similar to that obtained in patients without LBBB. A false positive results indicated ischemia of the interventricular septal region in a patient with normal coronary arteries, a known limitation of the method.

[Myocardial perfusion during exercise and rest in coronary patients. Evaluation with a thallium 201 analog (isonitrile-technetium 99 m)]. / Perfusión miocárdica en esfuerzo y reposo en pacientes coronarios. Evaluación con un análogo de talio 201 (isonitrio-tecnecio 99m).

Isonitrile-technetium, a Thallium 201 analog, was used for myocardial perfusion imaging in 12 patients with known coronary heart disease. 10-40 mCu of the isotope were injected at maximal effort during a Bruce stress test. Imaging was performed using 3 projections immediately after exercise and 24 hr later, using a gamma camera attached to a computer. Myocardial necrosis was detected with a sensitivity of 89% and specificity of 63%. Corresponding figures for stress induced ischemia were 89% and 100%. Accurate localization of ischemia or necrosis was obtained in 70% of all cases, improving to 100% in cases of total artery occlusion. These results, similar to those reported in the literature, encourage the use of Tc labeled isonitrile for myocardial perfusion imaging whenever Thallium 201 is difficult to obtain.