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1.
Sci Rep ; 13(1): 18184, 2023 Oct 24.
Artigo em Inglês | MEDLINE | ID: mdl-37875531

RESUMO

For the purpose of understanding, the governing system of partial differential equations for synovial fluid flow velocity and temperature distribution in the knee joint has been successfully solved for the first time. Therefore, such an article is shedding light on the convective diffusion of the viscous flow along the articular surfaces of the joints through the introduction of power-law fluids with different features of permeability, and stagnation point flow along a magnetic field. Henceforth, the frictional energy causes the knee joint's temperature to increase. By way of filtration, heated synovial fluid reaches the articular cartilage and provides heat to the bone and cartilage. The lubricant in the joint cavity is properly mixed with this cooled fluid. A rectangular region flow and diffusion model is used to define the issue, thermal diffusion and flow inside the intra-articular gap, as well as flow and thermal diffusion within the porous matrix covering the approaching bones at the joint. Using the similarity solution approach, the linked mixed boundary value problem is addressed. The fluid has been shown to resist moving into or out of the cartilage in certain sick and/or aging synovial joints, causing the temperature to increase. By changing the values of the parameters from their usual levels, it is observed that the temperature did increase in aged and sick joints which impact cartilage and/or synovial fluid degradation.

2.
Cancer Treat Res ; 185: 255-283, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37306913

RESUMO

From the time a person is diagnosed with cancer, a psychological sequalae of intense emotional challenges emerge for the patient as well as family members. Different stages require different types of psychosocial support including those for previvors, survivors, and people who need palliative care. Currently, there is an emphasis on not only providing psychological assistance to cope with emotional, interpersonal, and economic stresses, but training programs specially designed to activate personal and social resources to find happiness and meaning in adversity. Within this perspective, the chapter is divided into three sections, each considering the common mental health issues and positive changes and intervention and therapies for cancer patients, family members, caregivers, onco-staff, and professionals.


Assuntos
Neoplasias , Humanos , Sobreviventes
3.
Nanoscale ; 15(14): 6696-6708, 2023 Apr 06.
Artigo em Inglês | MEDLINE | ID: mdl-36938628

RESUMO

Cluster beam deposition is employed for fabricating well-defined bimetallic plasmonic photocatalysts to enhance their activity while facilitating a more fundamental understanding of their properties. AuxAg1-x clusters with compositions (x = 0, 0.1, 0.3, 0.5, 0.7, 0.9 and 1) spanning the metals' miscibility range were produced in the gas-phase and soft-landed on TiO2 P25-coated silicon wafers with an optimal coverage of 4 atomic monolayer equivalents. Electron microscopy images show that at this coverage most clusters remain well dispersed whereas EXAFS data are in agreement with the finding that the deposited clusters have an average size of ca. 5 nm and feature the same composition as the ablated alloy targets. A composition-dependant electron transfer from Au to Ag that is likely to impart chemical stability to the bimetallic clusters and protect Ag atoms against oxidation is additionally evidenced by XPS and XANES. Under simulated solar light, AuxAg1-x clusters show a remarkable composition-dependent volcano-type enhancement of their photocatalytic activity towards degradation of stearic acid, a model compound for organic fouling on surfaces. The Formal Quantum Efficiency (FQE) is peaking at the Au0.3Ag0.7 composition with a value that is twice as high as that of the pristine TiO2 P25 under solar simulator. Under UV the FQE of all compositions remains similar to that of pristine TiO2. A classical electromagnetic simulation study confirms that among all compositions Au0.3Ag0.7 features the largest near-field enhancement in the wavelength range of maximal solar light intensity, as well as sufficient individual photon energy resulting in a better photocatalytic self-cleaning activity. This allows ascribing the mechanism for photocatalysis mostly to the plasmonic effect of the bimetallic clusters through direct electron injection and near-field enhancement from the resonant cluster towards the conduction band of TiO2. These results not only demonstrate the added value of using well-defined bimetallic nanocatalysts to enhance their photocatalytic activity but also highlights the potential of the cluster beam deposition to design tailored noble metal modified photocatalytic surfaces with controlled compositions and sizes without involving potentially hazardous chemical agents.

4.
Nanomaterials (Basel) ; 12(23)2022 Nov 29.
Artigo em Inglês | MEDLINE | ID: mdl-36500877

RESUMO

Current study solves heat transfer and fluid flow problem in Newtonian and non-Newtonian nano-fluids through a permeable surface with a magnetic field effects which is done in the presence of injection and suction for the first time. In order to solve the governing partial differential equations numerically, we used the Runge-Kutta Fehlberg (RKF45) technique in which the similarity transformation method is applied. This approach converts the governing partial differential equations into ordinary differential equations. In this particular investigation nano-particles of copper, copper oxide, titanium dioxide, and aluminium oxide are studied by considering CMC/water as a base fluid with the effect of magnetic field on the classical Blasius and Sakiadis flows of nano-fluids. Validation is carried out using the previously obtained numerical findings. We looked at the power-law index (n), the volume fraction (φ) of nano-particles and the permeability parameter (fw) which affects the flow of nano-fluid and the transfer of heat. Non-Newtonian nano-fluid demonstrates superior performance in terms of heat transfer when compared to Newtonian nano-fluid in both the injection and the impermeable surfaces. Altering the nano-particles' composition, on the other hand, has a far greater impact on the heat transfer process that occurs during suction. Graphics show the impacts of governing physical parameters on Blasius and Sakiadis flow velocity, temperature, skin friction coefficient, and reduced Nusselt number. Physical and engineering interest are explored in detail.

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