Biodentine used as a pulp-capping agent in primary pig teeth.

PURPOSE: The purpose of this study was to assess and compare, in primary pig teeth, the pulp response after a pulpotomy using either Biodentine (a new tricalcium-silicate cement), white mineral trioxide aggregate (WMTA), or formocresol (FC) and repeat the same after direct pulp capping using either Biodentine, WMTA, or calcium hydroxide. METHODS: A total of 180 primary teeth from 9 healthy 4-month-old female pigs were divided into 3 experimental periods (7, 28, and 90 days) for each material used for the pulpotomy and direct pulp capping treatments. Seven, 28, and 90 days later, the animals were euthanized and the specimens were prepared for histological examination and evaluation. The data collected from the histological examinations were statistically analyzed using Kruskal-Wallis and Dunn multiple comparison tests. RESULTS: In pulpotomy groups, there was a significant difference between Biodentine and WMTA vs FC in terms of inflammatory cell response and hard tissue formation. In direct pulp capping groups, there was only a significant difference between Biodentine and calcium hydroxide in terms of hard tissue formation in a 7-day period. CONCLUSIONS: Biodentine and white mineral trioxide aggregate are both suitable, biocompatible materials for pulp capping in primary teeth of pigs.

Nanohydroxyapatite used as a pulpotomy and direct pulp capping agent in primary pig teeth.

PURPOSE: Recently, a fully Nanocrystalline Hydroxyapatie (NHA) paste has been introduced for augmentation procedures in osseous defects and is attracting increasing interest in medicine and dentistry. The purpose of the present study was to assess and compare the pulp response of pig primary teeth after capping with NHA and formocresol in pulpotomy and NHA and calcium hydroxide in direct pulp capping. METHODS: Forty teeth of two 4-month old pigs were pulpotomized and capped with these materials. Four weeks later, the animals were euthanized and the specimens were prepared for histological examination. RESULTS: In the pulpotomy groups, there was a significant difference between NHA and FC in terms of pulp response, hard tissue formation and normal pulp tissue preservation. In the direct pulp capping groups, there was no significant difference between NHA and Ca(OH)2 in terms of criteria mentioned above. CONCLUSIONS: The results of the present histological study show that, in the short term and in non-carious pig teeth, NHA appears to be biocompatible and provokes no moderate or severe inflammatory reaction in pulp tissue in both pulpotomy and direct pulp capping treatments.

Beta-tricalcium phosphate, white mineral trioxide aggregate, white Portland cement, ferric sulfate, and formocresol used as pulpotomy agents in primary pig teeth.

OBJECTIVE: The purpose of this study was to evaluate and compare the effects of formocresol (FC), ferric sulfate (FS), white mineral trioxide aggregate (WMTA), white Portland cement (WPC), and beta-tricalcium phosphate (beta-TCP) on pulpotomized primary teeth of pigs. STUDY DESIGN: Fifty teeth of three 3-month old pigs were pulpotomized with these materials. Three weeks later, the animals were euthanized and the specimens were prepared for histological examination. RESULTS: There was no significant difference between beta-TCP, WMTA, and WPC in terms of primary pulp response, hard tissue formation, and normal pulp tissue preservation. But, both FS and FC irritated the pulp tissue, provoking a more inflammatory pulp response than beta-TCP, WMTA, and WPC. CONCLUSION: Beta-TCP, WMTA, and WPC are histologically more effective pulpotomy agents than formocresol and ferric sulfate in primary pig teeth.