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J Laryngol Otol ; 121(4): 369-77, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-16716242

RESUMO

INTRODUCTION: Pre-operative endoscopic assessment of the distal extension of hypopharyngeal cancer is essential for proper surgical extirpation. This assessment is frequently not feasible in advanced, obstructing tumours. AIMS: To study the role of a proposed new diagnostic technique: intra-operative open oesophagoscopy, in distal assessment of advanced hypopharyngeal cancer. MATERIALS AND METHODS: A clinicopathological study, including 35 consecutive patients with obstructing hypopharyngeal cancer. RESULTS: Intra-operative open oesophagoscopy revealed inferior submucosal tumour extension in 19 out of 22 cases proven histopathologically, with a sensitivity, specificity and accuracy of 86, 100 and 91 per cent, respectively. Oesophageal skip lesions were detected in two cases. Intra-operative open oesophagoscopy findings surpassed data obtained from pre-operative radiological investigations and influenced the extent of resection performed. Accordingly, 19 patients had a total laryngopharyngectomy for local disease control, while 16 patients needed an additional total oesophagectomy. Histopathologically negative inferior resection margins were obtained in all cases. CONCLUSIONS: Intra-operative open oesophagoscopy was found to be a reliable diagnostic modality for distal assessment of obstructing hypopharyngeal cancer in cases in which pre-operative distal endoscopic examination was not feasible.


Assuntos
Carcinoma de Células Escamosas/diagnóstico , Esofagoscopia/métodos , Neoplasias Hipofaríngeas/diagnóstico , Adulto , Idoso , Carcinoma de Células Escamosas/patologia , Feminino , Humanos , Neoplasias Hipofaríngeas/patologia , Cuidados Intraoperatórios/métodos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Sensibilidade e Especificidade
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