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Nihon Kokyuki Gakkai Zasshi ; 44(11): 858-63, 2006 Nov.
Artigo em Japonês | MEDLINE | ID: mdl-17144587

RESUMO

SELAPINA is generic product of PL granule which is one of the most common forms of combination remedies for the common cold in Japan, and includes acetaminophen. We report a case of SELAPINA-induced pneumonia successfully treated with glucocorticoid pulse therapy followed by orally administered prednisolone. A 68-year-old woman, who had been treated for rheumatoid arthiritis with pulmonary involvement, took SELAPINA with an antibiotic for 6 days because of her cold symptoms. She then suffered a high fever, cough, dyspnea, vomiting and diarrhea. Chest radiograph and high-resolution computed tomography (HRCT) scan revealed diffuse interstitial shadows. SELAPINA-induced pneumonia was diagnosed because the blastoid transformation test using her peripheral blood lymphocytes was positive on stimulation with SELAPINA, but negative for other medicines.


Assuntos
Acetaminofen/efeitos adversos , Amiodarona/efeitos adversos , Pneumopatias/complicações , Pneumonia/induzido quimicamente , Doenças Reumáticas/complicações , Idoso , Artrite Reumatoide/complicações , Artrite Reumatoide/tratamento farmacológico , Combinação de Medicamentos , Feminino , Humanos
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