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Ann Rheum Dis ; 34(6): 520-3, 1975 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-176958

RESUMO

Production of a factor activating leucocyte procollagenase by tissue culture of rheumatoid synovium was shown. The activator was isolated, partly purified, and shown to be thermolabile, nondialysable, and had no activity toward casein, haemoglobin, histones, and PZ-peptide. The activity of the activator was partly decreased by trypsin.


Assuntos
Precursores Enzimáticos/metabolismo , Colagenase Microbiana/metabolismo , Artrite Reumatoide/enzimologia , Técnicas de Cultura , Humanos , Líquido Sinovial/enzimologia , Viscosidade
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