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2.
Artigo em Inglês | MEDLINE | ID: mdl-7735518

RESUMO

The evolution of both specific and nonspecific IgE in a long-term follow-up after surgery in patients with human hydatid disease was studied. Enzyme immunoassays using cyanogen bromide-activated cellulose discs as solid phase were employed. One hundred and nine postoperative serum samples from 26 patients undergoing surgery for hydatid disease were studied. Imaging studies were also carried out during the follow-up. In 8 of 26 patients, remaining cysts were detected during the follow-up. One year after surgery, total IgE levels decreased to normal values in 84.6% of the total number of patients, in 94.5% of the cases in which no remaining cysts were detected, and in 62.5% of the patients with remaining hydatid cysts. These data highlight the poor value of an isolated postoperative IgE determination as a diagnostic marker for remaining hydatidosis. On the contrary, 1 year after surgery, the levels of anti-Echinococcus IgE decreased in 55% of the patients without residual cysts and in 50% of the total number of patients. In six patients without remaining hydatid cysts, the levels of specific IgE increased 1 year after the surgery. In the group of patients with remaining cysts only in three patients did the values of specific IgE decrease, although they remained significant. Thus, 1 year after surgery, anti-Echinococcus IgE levels were still evident in all patients, although in those without remaining cysts there was a predominance of decreasing values.(ABSTRACT TRUNCATED AT 250 WORDS)


Assuntos
Anticorpos Anti-Helmínticos/sangue , Equinococose/imunologia , Imunoglobulina E/sangue , Adulto , Animais , Equinococose/cirurgia , Echinococcus/imunologia , Seguimentos , Humanos , Técnicas Imunoenzimáticas
3.
Allergol Immunopathol (Madr) ; 16(1): 49-52, 1988.
Artigo em Inglês | MEDLINE | ID: mdl-3289333

RESUMO

The levels of total IgE and specific IgE in preoperative sera from 29 adult patients with surgically confirmed hydatidosis were studied by means of enzyme-immunoassay. Sera from 88 healthy donors were likewise studied. Findings showed that in the majority of the hydatidosis cases there was an increase of specific IgE and total IgE although individual variance was significant. Determination of total IgE as the only serological diagnostic test is not valid, since 27.5% of patients showed a total IgE level within normal values. Moreover, the determination of specific IgE has more diagnostic value than that of total IgE although it must be taken into account that in 7% of human hydatidosis cases there are no detectable levels of anti-Echinococcus IgE.


Assuntos
Anticorpos Anti-Helmínticos/análise , Equinococose/imunologia , Imunoglobulina E/análise , Adulto , Equinococose/cirurgia , Humanos , Técnicas Imunoenzimáticas
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