RESUMO
The Prevotella genus is a normal constituent of the oral microbiota, and is commonly isolated from mechanically treated polymicrobial infections. However, antibiotic treatment is necessary for some patients. This study compared the antibiotic susceptibility and the presence of resistance genes in clinical oral isolates of P. intermedia, P. nigrescens, and P. melaninogenica. Antibiotic susceptibility was assessed using the agar dilution method. PCR confirmed the species and resistance gene frequency in the Prevotella species. The frequencies of species P. intermedia, P. nigrescens, and P. melaninogenica were 30.2%, 45.7%, and 24.1%, respectively. No isolates of P. intermedia were resistant to amoxicillin/clavulanic acid, tetracycline, or clindamycin. P. nigrescens and P. melaninogenica were resistant to amoxicillin/clavulanic acid and tetracycline at frequencies of 40% and 20%, respectively. P. intermedia was resistant to metronidazole at a frequency of 30%, P. nigrescens at 20%, and P. melaninogenica at 40%. P. nigrescens and P. melaninogenica were resistant to 50% and 10% clindamycin, respectively. The gene most frequently detected was tetQ, at 43.3%, followed by tetM at 36.6%, blaTEM at 26.6%, ermF at 20%, cfxA, cfxA2, and nimAB at 16.6%, and nimAEFI at 3.3%. P. nigrescens was the species with the highest resistance to antibiotics such as amoxicillin/clavulanic acid, amoxicillin, and clindamycin, in addition to being the species with the largest number of genes compared to P. intermedia and P. melaninogenica.
RESUMO
Las mujeres están subrepresentadas en la producción científica. Diversos estudios demuestran que las mujeres tienen menor participación en la autoría de artículos científicos. El objetivo del presente estudio fue determinar si el sexo se asocia con el impacto académico en investigadores de países latinoamericanos. Para esto se comparó el índice h y el número de citas. Se realizó un estudio bibliométrico con datos de la página Webometrics Ranking of World Universities que publica periódicamente "ránquines" de investigadores según sus perfiles en Google Académico. Se revisaron los 150 primeros puestos de 12 países de Latinoamérica y se evaluaron las diferencias en el impacto académico según el sexo. De un total de 1 750 investigadores, solo el 17,3 por ciento (303) fueron mujeres. De los 12 países analizados, la mayoría (ocho) no presentó diferencias significativas en el impacto académico según el sexo y solo cuatro presentaron estas diferencias, aunque con un tamaño del efecto pequeño (r < 0,3). Menos de la quinta parte de los investigadores considerados en la muestra fueron mujeres; sin embargo, en la mayoría de los países el impacto académico de las mujeres resultó ser similar y en algunos casos superior al de sus homólogos masculinos(AU)
Women are underrepresented in scientific production. Several studies show that women have less participation in the authorship of scientific articles. The objective of the present study was to determine if sex is associated with academic impact in researchers of Latin American countries. A comparison between the h-index and the number of citations was carried out. A bibliometric study was conducted with data from the Webometrics Ranking of World Universities page that periodically publishes rankings of researchers according to their profiles in Google Scholar. The first 150 positions from 12 Latin American countries were reviewed and the differences in academic impact according to sex were evaluated. Of a total 1 750 researchers, only 17.3 percent (303) were women. Of the 12 countries analyzed, the majority (8) did not present significant differences in academic impact by sex and only four presented these differences, although with a small effect size (r < 0.3). Less than one-fifth of the researchers considered in the sample were women; however, in most countries the academic impact of women was similar and in some cases greater than that of their male counterparts(AU)