[The diagnosis of Cushing's disease by the nocturnal dexamethasone administration test]. / Diagnóstico de la enfermedad de Cushing mediante la prueba de administración nocturna de dexametasona.

Prospective study performed at the General Hospital, National Medical Center, XXI Century, Endocrinology Ward, Mexico-City, to compare the diagnostic sensitivity in Cushing's disease of the oral high doses (8 mg) dexametazone suppression test in single doses with nocturnal administration (DXM-N) and the classic doses of two days (DXM-C). Fourteen patients with hypercortisolism were studied; on thirteen the hypophyseal origin was surgical confirmed. Sensitivity of high doses of oral dexametazone test was proved by using serial samples of serum cortisol; the Fisher test was used for analysis of the suppression of serum cortisol after the test was done.

[Thyroid hemiagenesis. Report of 3 cases and review of the literature]. / Hemiagenesia tiroidea. Reporte de 3 casos y revisión de la literatura.

The absence of one lobe of the thyroid gland is named thyroid hemiagenesis, the left is affected more frequently (80 percent), in the 50 percent is associate with isthmus agenesis. Predominant in the women, with relation 3:1, the oppose lobe may be of big size and in the 38-47 percent have alteration in the function, of which the hyperthyroidism is more frequently. In 1896 Handfield-Jones reported the first case, having in this moment 118 cases in the world literature, we reported three more, one of which is the second associated with hyperparathyroidism and other is the third with hypothyroidism. The diagnosis was made with I-131 thyroid gammogram and neck echosonography that which evidence the hemiagenesis, and was not necessary to realize the thyroid gammagram with thyroid stimulation hormone. In different series of surgery, necropsis or by thyroid illness the frequency of thyroid hemiagenesis is estimate below 1 percent.