[Mast cell infiltration of the stroma and free heparin in the blood in breast cancer]. / Tuchnokletochnaia infil'tratsiia stromy i svobodnyi geparin krovi pri rake molochnoi zhelezy.

The study included mast cell content assay in breast cancer stroma, free blood heparin measurement and its variation versus treatment and disease outcome. In clinically unfavorable cases, tumors displayed equal levels of mast cells whatever treatment procedure (surgery, chemotherapy + surgery). However, in patients with aggressive course, mast cell concentration decreased 3-fold following surgery whereas it rose significantly after combined therapy. In clinically favorable cases, free blood-heparin level was half the one in those with aggressive course.

[Use of a personal computer for storage and statistical processing of information on patients with breast cancer]. / Ispol'zovanie personal'nogo komp'iutera dlia khraneniia i statistikoi obrabotki informatsii o bol'nykh rakom molochnoi zhelezy.

The breast cancer data analysis system (BCDAS) was developed to be used in personal computers to enter, store and process data on breast cancer patients. It is a multi-purpose system adjustable to other applications.

[Use of laboratory methods in the formation of groups at risk for cancer of the breast]. / Ispol'zovanie laboratornykh metodov dlia formirovaniia grupp riska po raku molochnoi zhelezy.

The features of the homeostasis systems functioning in mammary carcinoma patients and in subjects at risk of this condition are analyzed. The pattern of the reactions of the homeostasis parameters, characteristic of each diseases, suggests that laboratory examinations may contribute to the efficacy of early diagnosis of mammary carcinoma in prophylactic check-ups of females.

[The extent of the surgical intervention and the prognosis of patients with stage III breast cancer]. / Ob''em operativnogo vmeshatel'stva i prognoz u bol'nykh rakom molochnoi zhelezy III stadii.

The report is concerned with comparison of the effectiveness of surgery for breast tumors (stage III) after Halsted and Patey. The 5-year survival rates, relapse and tumor dissemination proved nearly identical in both study groups. A modified procedure of radical mastectomy after Patey was used for treatment of stage III breast tumors which did not extend through the underlying tissues of the chest wall.

[Working classification of spinal tumors and their surgical treatment]. / Rabochaia klassifikatsiia opukholei pozvonochnika i ikh khirurgicheskoe lechenie.

A working classification of vertebral tumors is discussed. The classification is based on tumor process expansion, presence of soft-tissue component and the degree of vertebral and neurologic complications. The extent and type of surgical procedure are determined in accordance with the authors' approach to tumor process staging.

[Use of cyclophosphane and amphotericin B on patients with disseminated forms of chondrosarcoma]. / Primenenie tsiklofosfana i amfoteritsina "B" u bol'nykh s rasprostranennymi formami khondrosarkomy.

The results of amphotericin B and cyclophosphamide treatment of 10 cases of chondrosarcoma are discussed. A marked (50-90%) regression of tumors and metastases and complete remission for 3-18 months were observed in 9 cases. Decompression laminectomy resulted in regression of neurologic symptoms in a case of chondrosarcoma disseminated to the spinal column with concomitant constriction of the spinal cord. This effect was obtained during remission following chemotherapy.