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1.
Sci Rep ; 13(1): 1066, 2023 Jan 19.
Artigo em Inglês | MEDLINE | ID: mdl-36658209

RESUMO

The mechanical properties of coconut shell ash (CSA) reinforced polyester composite have been optimized. Various test specimens were developed by dispersing 10, 20, 30 and 40 wt.%, of CSA in unsaturated polyester resin in decreasing particle sizes of 40, 30, and 20 µm in an open mould using hand lay-up technique. Tensile, flexural, and impact strengths, as well as tensile and flexural moduli and Shore D hardness of all test samples were determined. The results showed that 10-20 wt.% CSA increased tensile, flexural, impact strengths and flexural modulus for all particle sizes, but 30-40 wt. % CSA engendered depreciation in corresponding performance. For all particle sizes, 10-40 wt. percent CSA resulted in an increase in tensile strength, whereas 10-40 wt. percent resulted into a linear increase in Shore D hardness. Further observation portrayed that in each case, the finest CSA (20 µm) have the optimum result. Statistical analysis carried out on experimental outcomes confirmed the experimental variables (particle proportion and sizes) to be significant. From the surface plot, the strength responses revealed more dependence on the individual variables than their interactions. Regression models developed for individual responses are termed statistically fit in representing the experimental data.

2.
Sci Rep ; 12(1): 17054, 2022 10 12.
Artigo em Inglês | MEDLINE | ID: mdl-36224225

RESUMO

Improper discharge of waste dry cell batteries and untreated antibiotics laden effluents to the environment pose serious threat to the sustenance of the ecosystem. In this study, synthesis of reduced graphene oxide-ZnO (rGO-ZnO) nanocomposite was achieved via a bioreduction process using waste dry cell battery rod as graphene oxide (GO) precursor. The nanocomposite was applied in the ultraviolet photocatalytic degradation of chloramphenicol (CAP) at 290 nm in the presence of hydrogen peroxide. RGO-ZnO nanocomposite was characterized by SEM, TEM, XRD, BET and FTIR. TEM image of the nanocomposite revealed a polydispersed, quasi-spherical zinc oxide on a coarse reduced graphene oxide surface. XRD patterns showed sharp, prominent crystalline wurtzite hexagonal phases of ZnO and rGO. BET surface area of the nanocomposite was 722 m2/g with pore size of 2 nm and pore volume of 0.4 cc/g. % photo-removal efficiency increased with increasing irradiation time but diminished at higher pH, temperature and CAP concentration. Photocatalytic adsorption process fitted more accurately into the Freundlich model (R2 = 0.99) indicating a multilayer adsorption mechanism. 92.74% reduction in chemical oxygen demand (COD) level of veterinary effluent was obtained after treatment with the nanocomposite thus affirming its effectiveness in real waste water samples.


Assuntos
Óxido de Zinco , Antibacterianos , Catálise , Cloranfenicol , Ecossistema , Grafite , Peróxido de Hidrogênio , Águas Residuárias , Óxido de Zinco/química
3.
Heliyon ; 6(7): e04512, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32775718

RESUMO

This study evaluates the effect of treated and untreated jute fiber/eggshell particulate reinforced cement-paper matrix composites for ceiling board application. Treated jute fiber (TJF) was obtained by immersing untreated jute fiber (UJF) into 1.25 M sodium hydroxide (NaOH) solution in a shaker water bath maintained at 40 °C for 4 h. Eggshells (ESP) were pulverized and sieved to -75µm. Samples were prepared by varying the fiber volume fraction from 0.5 to 2.5 wt.% in the composites. While other constituents such as the binder (cement) and eggshell were kept constant. An hydraulic press cold compaction molder was utilized in the production of the hybrid composites in a predetermined mix ratio designed based on previous research. The samples produced were cured for 7 and 14 days, then sundried for 36 h. The physical, thermal, mechanical and wear behaviour of the produced composites were evaluated while the surface morphology of the fractured splitting tensile samples were analyzed. The result reveals that TJF/ESP hybrid composites had better performance than UJF/ESP hybrid composites in most of the tests carried out. Increase in the number of curing days was found to also enhance the properties of the composite produced in majority of the test evaluated. The 0.5 wt.% UJF/ESP gave the least performance of all the composites developed. While 2.5 wt. % TJF/ESP showed an optimum properties among the composites tested. When compared with standard, it is concluded that the hybrid composites developed can be suitable for ceiling boards and also find possible application in wall partitioning.

4.
Heliyon ; 6(7): e04444, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32695915

RESUMO

Quenching is one of the major processes of heat treatment of medium carbon steel that aims at improving its mechanical properties. However, the effectiveness of this process is dependent on several control factors that must be maximized to obtain optimum results in terms of hardness, yield strength, ultimate tensile strength among others. This study aims at optimizing the process of improving the mechanical properties of medium carbon steel by varying some key factors like the quenchant used (A), heat treatment temperature (B), and soaking time (C). The measured responses in this study were the hardness, yield strength (YS), and ultimate tensile strength (UTS). Optimization was conducted in two stages. The first stage dealt with the mono-optimization of process parameters using Taguchi's Signal-to-Noise (S/N) ratio. A total of nine (9) experiments were performed based on standard L9 orthogonal array because each of the three control factors has three (3) levels. The second stage was multi-objective optimization using Taguchi-based grey relational analysis (GRA). The optimal conditions for hardness, YS, and UTS were obtained at A2B3C3, A3B2C3, and A3B3C3, respectively. Using ANOVA as statistical analysis, it was observed that the soaking time was the main control factor for all three measured responses (31.95% contribution ratio for hardness, 62.46%, and 66.76% for YS and UTS, respectively), while the quenchant had the least contribution. Analysis of the Taguchi-based GRA revealed that the results obtained are in total conformance to that of the Taguchi method, with soaking time having the highest contribution ratio of 69.41%.

5.
ScientificWorldJournal ; 2020: 7462758, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32724303

RESUMO

The increase in demand for thermoplastics as a light-weight material for automobile application and other commercial purposes prompts more research into the available polymer resources. In this research, the possibility of enhancing the performance of recycled waste plastics (RWP) as polymer-based composites was examined. Particulate snail shell was obtained by grounding and sieving snail shells to obtain 53-63 µm passing which was used as reinforcement in the recycled waste plastics. The composites were developed by adding varying proportions of the snail shell particulate (SSP) to RWP using a randomly dispersed process in a hot compression moulding machine maintained at 190°C for 7 min. Selected properties of SSP-reinforced RWP composites were examined. The results showed an appreciable enhancement in the properties of composites developed compared to an unreinforced RWP matrix that serves as control. The ultimate tensile strength was enhanced by about 64%, while Young's Modulus and impact strength were enhanced by 37% and 29%, respectively. Wear and water repellant potentials were highly enhanced with the addition of 15 wt% of SSP with values of about 52% and 91%, respectively. This revealed that high content of the SSP contributes to the improvement of the strain-hardening potentials of the developed composites. The results showed that this composite material can be suitably adapted for use in the interior of automobiles as door sills or the floor panel.

6.
Sci Rep ; 10(1): 11105, 2020 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-32632175

RESUMO

This research presents the behavior of dombeya buettneri fiber/graphite hybrid composites which was studied to harness a favorable balance between the inherent advantages and disadvantages of natural and synthetic reinforcements. The fibers after extraction were chemically treated for surface modification. The composite was developed using compression molding process by randomly dispersing the reinforcements in the polypropylene matrix in predetermined proportions. The developed samples were tested to ascertain the response of the materials to the selected properties. Experimental results showed that hybrid composite sample C which is a blend of 12 wt% dombeya buettneri fiber (DBF) and 8 wt% graphite particle (GP) gave enhanced results in many of the properties which includes; hardness, impact, thermal insulation and abrasion resistance properties. Also, the hybrid composites sample denoted as sample E which is the blend of 6 wt% DBF and 14 wt% GP produce higher enhancement in the flexural properties and Young's Modulus of Elasticity than other samples. Composite sample reinforced with dombeya buettneri fiber as single reinforced composites performed more in ultimate tensile strength compared to other samples while graphite particle reinforced sample emerges as the best in thermal conductivity. Diffusion of water into the composites also obeys Fick's law where sample C was seen to be the best among the composites. It was therefore, discovered that the synergy between the two reinforcements has encouraged the improvement of polypropylene (PP) properties in a unique mode.

7.
ScientificWorldJournal ; 2020: 2756734, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32669981

RESUMO

The inhibitive effect of mebendazole (MBZ) on the corrosion of low-carbon steel in H2SO4 was investigated by gravimetric and electrochemical techniques as well as examination of specimens in the scanning electron microscope with attached energy dispersive X-ray spectrometer (EDS). From gravimetric analysis, the highest inhibition efficiency of about 96.6% was obtained for 1.0 g of inhibitor in H2SO4 solution at 24 h, while with longer exposure times of between 72 to 120 h, the efficiencies averaged between 92 and 95%. Tafel extrapolations from the polarization curves showed that 1.0 g MBZ gave a maximum inhibition efficiency of approximately 99% for the investigation conducted at 30°C, whereas 1.5 g of MBZ gave a maximum inhibition efficiency of about 85% at 60°C. Inhibition efficiency increased with increasing concentrations of MBZ and decreased at elevated temperatures. The inhibitive action was attributed to physical adsorption of MBZ species on the mild steel surface which followed the Langmuir adsorption isotherm. MBZ performed as a mixed-type inhibitor on mild steel in dilute H2SO4.

8.
Heliyon ; 6(6): e04157, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32551390

RESUMO

This paper reports the physical and mechanical properties of Entada mannii particulates reinforced composites. Polypropylene (PP) based composites filled with Entada mannii ash particulates was produced using the compression moulding. The thermal properties, structural characteristic and morphology of the composites and ash particulate were studied. Tensile properties, impact strength and flexural properties were used to evaluate the mechanical behaviour of composites. Tensile properties, elastic modulus and hardness properties of the fiber ash polymer composites were improved with aggregate fiber ash loading by 58 %, 41 % and 56 % relative to pure PP composites while there was a drop in impact strength by 56 % as compared with pure PP. Flexural strength of the fiber ash reinforced composites was enhanced significantly with increasing ash particulate loading by 45% and 32% respectively. The Fourier transform infrared spectroscopy (FTIR) revealed that changes occur due to stretching of hydrogen bond network and lignin was remove completely during carbonation process. Fracture surface morphology of fiber ash reinforced composites gave credence to the fact that good wetting between the particulate and the matrix was achieved.

9.
Heliyon ; 6(6): e04008, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32548316

RESUMO

In this research, developed finite element codes were used to study the effective elastic modulus and stress-strain distribution profiles of epoxy resin filled with 6 wt. % microparticles of kaolinite. The random distribution of the particles was microstructurally regenerated with Digimat MSC software and random sequential algorithm codes in epoxy matrix. Stochastic representative volume element models of the composites were developed and analyzed under periodic boundary conditions. For validation, the predicted result by finite element analysis was compared with that of Mori-Tanaka's mean field homogenization scheme, selected micromechanical models and experiment. All the results indicated that 6 wt. % of kaolinite microparticles can improve the elastic modulus and load-bearing capacity of epoxy resin with <5 % error between predicted and actual results. The microstructure, phase identification and chemical characterization of the composite were also studied with scanning electron microscopy, x-ray diffraction spectroscopy and energy-dispersive x-ray spectroscopy, respectively. In addition, the particle size and distribution of the kaolinite in the epoxy matrix were experimentally investigated.

10.
Heliyon ; 6(4): e03765, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32368642

RESUMO

Hard tissue regeneration and regrowth have continued to be a challenge in the field of conventional medicine in this 21st century. Over the years, the regrowth of broken bones and diseased hard tissue has remained a major concern in medical research. Since the discovery of hydroxyapatite (HA), a bioceramic compound that possesses the ability to activate bone regrowth and bond directly with regenerated bone, it has subsequently become an indispensable biomaterial. Currently, it is being used across the medical fields due to its exceptional biocompatibility. This became plausible because the main mineral phase of mammalian bones is HA. It has found application in various medical fields like medical instruments, drug delivery, bone and tooth fillers, prosthetics, orthotics, and in-vitro implants. As the importance of HA geometrically increases, it is necessary to critically evaluate and propose the most economic process of synthesizing and manufacturing this important bioceramic material. This review, therefore, highlights the different sources of HA and the synthesis/production methods for each source with a strong emphasis on the environment. Thus, the appraisal was carried out based on the properties of the derived HA. Such properties include but are not limited to geometry, particle size, morphology, thermal stability, and stoichiometry to suggest the most economic and environmentally sustainable sources and processing routes.

11.
Heliyon ; 5(7): e02028, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31317082

RESUMO

High density polyethylene (HDPE) composites reinforced with short bamboo fibre (BF) were fabricated by compression moulding technique. BF were extracted from bamboo culm and treated with 0.5 M NaOH. The composites were developed by melt-compounding various weight fractions (2, 4, 6, 8 and 10 wt.%) of the treated BF with HDPE with the aid of single screw laboratory extruder at a temperature of 180-220 °C. The extrudates were thereafter moulded into various test specimens with the aid of carver laboratory press at a temperature of 230 °C and applied pressure of 0.2 kPa for 10 min. Effect of the treated BF on the mechanical properties and water uptake behaviour of the composites were studied. The results revealed that there was enhancement in the mechanical properties from 2 - 4 wt.% of BF while the water absorption rate increased with increase in the fibre weight fraction. The morphology of the composites showed that there was a homogenous dispersion of BF at lower weight fraction, although fibre agglomeration was noticed at higher weight fraction. The results of this study revealed that treated bamboo fibres are suitable for reinforcing HDPE.

12.
Data Brief ; 21: 1496-1503, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30510979

RESUMO

The dataset represented in this article describe a diagnostic schedule for a defective LC-195V5 CNC milling machine using PERT. The efficiency of the technicians who repaired the CNC machine tools was measured based on fault location within the shortest possible time. A diagnostic schedule was developed which showed the sequential means of troubleshooting within a possible shortest time. Two approaches were employed. Forward Pass (FP), which involved the diagnosis from electrical parts through Computer (CNC) to mechanical components and Backward Pass (BP) which involved the diagnosis from computer component through electrical parts to mechanical parts. Three different levels of expertise (trials) were used for each of the mode of diagnosis and the time to diagnose each component part was recorded. Two separate PERT network diagrams were drawn based on the inter-relationship of the component parts of the machine and their Critical Paths were determined.

13.
Data Brief ; 20: 1224-1228, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30238031

RESUMO

Several wastes can be instrumental in the improvement of the mechanical properties of medium carbon steel when quenched. The quenching media employed such as coconut water (CW), pap water (PW) and spent engine oil (SPE) have been largely considered as wastes. The data in this article are related to the research article titled "Mechanical Properties Improvement Evaluation of Medium Carbon Steels Quenched in Different Media" (Ikubanni et al., 2017) [1]. The article provides information on the mechanical properties evaluation of medium carbon steel quenched in different media. Twenty-seven (27) samples of medium carbon steel samples were heated to temperatures of 730 °C, 760 °C and 790 °C and soaked for 30, 45 and 60 min respectively. The test results recorded include hardness value, yield strength (YS) and the ultimate tensile strength (UTS) for each of the samples at different heating temperatures and soaking time for the different quenching media.

14.
Afr. j. infect. dis. (Online) ; 10(1): 25-28, 2016. tab
Artigo em Inglês | AIM (África) | ID: biblio-1257216

RESUMO

Background: Toxoplasma gondii and Neospora caninum are protozoans infecting a wide range of mammals; the etiologic agents of Toxoplasmosis and Neosporosis respectively; This study investigated the prevalence of antibodies to Toxoplasma gondii and Neospora caninum in dogs from southwestern Nigeria. Materials and Methods: A total of 233 serum samples were obtained from both urban and rural areas of Oyo state; Nigeria and tested by the western blotting technique for specific IgG to T. gondii and N. caninum.Results: The seroprevalence obtained for T. gondii was 19% (44/233) and 2.1% (5/233) for N. caninum in the dogs examined. Overall; the prevalence of antibodies to T. gondii was more significant than for N. caninum (P 0.0001). T. gondii infection was also found to be more significant in roaming than in caged dogs (P 0.05). There was no significant association of other factors (age; breed; history of rabies vaccination; use of dog and the level of education of owner) with the prevalence of T. gondii and N. caninum infection. Conclusion: This report revealed that T. gondii infection is more common than N. caninum infection in Nigerian dogs; it suggests that improper housing and feeding of dogs could increase the risk of exposure to T. gondii infection. This is the first study to investigate the seroprevalence of N. caninum antibodies in Nigerian dogs and T. gondii antibodies in dogs in southwestern Nigeria


Assuntos
Cães , Neospora , Nigéria , Estudos Soroepidemiológicos , Toxoplasmose , População Urbana
15.
Niger Med J ; 55(2): 116-20, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24791043

RESUMO

BACKGROUND: Immunity in pregnancy is physiologically compromised and this may affect cluster of differentiation four (CD4) count levels. It is well established that several factors affect CD4 count level in pregnancy. This study aims to determine the effects of maternal age, gestational age, parity and level of education as they influence CD4 count in pregnancy and also to determine the mean and reference range of CD4 count in pregnancy in Lagos, Nigeria. MATERIALS AND METHODS: A descriptive cross-sectional study was carried out at Ante-natal clinics in Lagos State, Nigeria. About 5 mls of blood was collected into Ethylene Diamine Tetracetic Acid (EDTA) bottles from HIV-negative pregnant women in various gestational ages of pregnancy. CD4+ cell count and full blood count of all samples were done within 3 hours of collection. The descriptive data was given as means ± standard deviation (SD). Pearson's chi-squared test and correlation were used for analytical assessment. RESULTS: A total of 74 pregnant women were recruited. The age range was 19-41 years and a mean age of 30.42 ± 5.34 years. The CD4+ cell count was not statistically significant when compared with participants ages P = 0.417, neither with gestational ages P = 0.323, nor with parity P = 0.247 nor level of education P = 0.96. An overall mean CD4+ cell count was 771.96 ± 250 cells/µl and the range was 193-1370 cells/µl. CONCLUSION: Maternal age, gestational age, parity and level of education had no significant effects on CD4+ cell count levels in pregnancy. The mean CD4+ cell count of HIV-negative pregnant women in Lagos is 771.96 ± 250 cells/µl.

16.
Niger J Clin Pract ; 17(2): 163-7, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24553025

RESUMO

BACKGROUND: Patients with sickle cell disease have an amplified vulnerability to urinary tract infection, because of abnormally dilute and alkaline urine, which favors bacterial proliferation. This is due to altered blood flow in the renal vasculature, which causes papillary necrosis and loss of urinary concentrating and acidifying ability of the nephrons. Asymptomatic bacteriuria is common, but the prevalence in populations varies widely with age, gender, sexual activity and the presence of genitourinary abnormalities. The aim of this study was to determine the prevalence of significant bacteriuria in symptomatic and asymptomatic sickle cell patients in Lagos. MATERIALS AND METHODS: This was a cross-sectional study of patients attending the sickle cell clinics of Lagos State University Teaching Hospital, Ikeja. Single voided aseptically collected mid-stream urine was obtained from each patient and all samples processed immediately, were sent for urinalysis and culture. Isolates were considered significant if there were ≥10 5 colony forming units per milliliter (CFU/ml) with two or less isolates, doubtful significance if ≤10 5 CFU/ml. Significant isolates were selected for identification. Data were analyzed using the Statistical Package for Social Sciences (SPSS) version 16.0 (SPSS, Inc., Chicago, Ill). RESULTS: A total of 100 consenting participants were recruited into the study. The mean age was: 23.42 ± 8.31 years and a range of 14-50 years. Only 9% (9/100) had significant bacteriuria while 44.4% (4/9) participants who had significant bacteriuria were asymptomatic. Escherichia coli was isolated in 66.6% (6/9) participants who had significant bacteriuria while Klebsiella oxytoca, Klebsiella pneumonia and Staphylococcus aureus (11.11%) was isolated in each of the remaining three participants. CONCLUSIONS: Significant bacteriuria is found in only one-tenth of sickle cell patients, nearly half of the participants who had significant growth had asymptomatic bacteriuria.


Assuntos
Anemia Falciforme/complicações , Bacteriúria/epidemiologia , Centros de Atenção Terciária , Adolescente , Adulto , Bacteriúria/etiologia , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nigéria/epidemiologia , Prevalência , Estudos Retrospectivos , Adulto Jovem
17.
J Blood Med ; 4: 39-42, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23717053

RESUMO

INTRODUCTION: A few reports have linked regular blood donation to the lowering of parameters of lipid profile. Estimating the lipid profile is an accepted method of assessing an individual's risk for coronary heart disease, particularly if there is evidence of lipid peroxidation. Regular blood donation may lower iron stores, and this in turn lowers lipid peroxidation. This study was carried out to determine the effect of blood donation on lipid profile. MATERIALS AND METHODS: Eighty-two participants consented to participate and were enrolled into the study, 52 of whom were regular blood donors (study group) and 30 were non-donors (control group). Venous blood (10 mL) was drawn from each subject into new plain screw-capped disposable plastic tubes. This was allowed to clot and the serum was used to determine total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein. RESULTS: The mean total cholesterol (4.66 ± 0.86 mmol/L), triglycerides (1.22 ± 0.64 mmol/L), and low-density lipoprotein (2.32 ± 0.73 mmol/L) were significantly lower in the regular blood donors than the control group (5.61 ± 1.26 mmol/L, 1.77 ± 2.9 mmol/L, and 3.06 ± 0.89 mmol/L, respectively; P < 0.05 in all cases). Also, while 42% of the study group had a low/high-density lipoprotein ratio of at least three, about 57% of the control group had a ratio of at least three (P = 0.21). CONCLUSION: Regular blood donation may be protective against cardiovascular disease as reflected by significantly lower mean total cholesterol and low-density lipoprotein levels in regular blood donors than in non-donors.

18.
Niger J Clin Pract ; 15(2): 136-41, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22718159

RESUMO

OBJECTIVES: Hereditary resistance to activated Protein C (Factor V Leiden) is the commonest genetic defect known to confer a predisposition to thrombosis. This study aims to determine the prevalence of activated protein C resistance (APCr) in Lagos, and to determine if any association exists between APCr and ABO, Rhesus blood types, and hemoglobin phenotypes. MATERIALS AND METHODS: A functional APCr test was conducted on healthy adult volunteers to get a Factor-V-related activated protein C ratio (APC-V ratio). APCr due to Factor V mutation was indicated when the APC-V ratio is below a cut-off value that was determined by calibration. Subjects' hemoglobin, red cell ABO, and Rhesus phenotypes were determined by standard methods. RESULTS: Six (2%) of 297 participants with normal baseline coagulation screening tests had functional resistance to activated protein C (APC-V ratio < 2). None of the six subjects with APCr had history of venous thromboembolism. One of the six subjects was a female but the male sex did not demonstrate a risk of inheritance of APCr (P = 0.39). Four (67%) of the six subjects with APCr were non-O blood group. Whereas only two (0.9%) of 226 non-A subjects (blood groups 0 and B) had APCr, 4 (6%) of 71 subjects with A gene (blood groups A and AB) had APCr. The inheritance of A gene appears to constitute a risk to inheritance of APCr (P = 0.03). No association was demonstrable between APCr and hemoglobin phenotypes. CONCLUSION: Only 2% of the studied population had resistance to APC. The inheritance of blood group A may be a predisposition to APCr.


Assuntos
Sistema ABO de Grupos Sanguíneos/sangue , Resistência à Proteína C Ativada/epidemiologia , Hemoglobinas , Sistema do Grupo Sanguíneo Rh-Hr/sangue , Resistência à Proteína C Ativada/genética , Adolescente , Adulto , Fator V , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nigéria/epidemiologia , Fenótipo , Prevalência , Adulto Jovem
19.
Niger Med J ; 52(1): 55-59, 2011 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21969222

RESUMO

OBJECTIVES: To determine the rate and pattern of disclosure and non disclosure of HIV serostatus among people living with HIV and the psychosocial impact of disclosure. METHODS: Participants were drawn from the adult HIV clinic at the Lagos University Teaching Hospital, Lagos, Nigeria. An interviewer-administered questionnaire was used to collect data from consenting participants that included socio-demographic information, pattern and reason for non-disclosure and the possible consequences of disclosure of HIV serostatus to their sexual partners. RESULTS: Four hundred and ninety nine respondents with a mean age of 37.3 ± 9.6 years were recruited into the study. There were 157 males and 342 females. Majority of the participants were married (62%) and belonged to the low socio-economic class. Overall 61.5% (307 of 499) had disclosed their status to sex partner(s). Gender, social class and length of year of diagnosis were not associated with disclosure but number of sexual partners was strongly associated with non disclosure. P=0.0063. The most common reason for non-disclosure was fear of rejection (65%). Majority (96.7%) of those who disclosed their status had no regret and majority (81.1%) of those who had not disclosed had protected sex. After counseling, only18.8% (36 of 192) of those that had not disclosed thought that the counseling had helped them overcome the fear of disclosure and were willing to disclose. CONCLUSION: Many people would disclose their HIV serostatus to sex partner(s). Protected sex (through the use of condom) is widely accepted in our setting.

20.
Niger Postgrad Med J ; 18(3): 177-81, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21909146

RESUMO

AIMS AND OBJECTIVES: The study aimed at reviewing the utilisation of blood / blood products and haematological profile changes, with a view to developing a hospital transfusion guideline in open heart surgery in Nigeria. MATERIALS AND METHODS: The surgeries were performed at the intensive care unit theatre of Lagos State University Teaching Hospital. Eligibility for surgery was determined by the Cardiologist and the cardiovascular Surgeon based on clinical presentation, electro- and echocardiography assessments among other tests. Fourteen open-heart surgeries were conducted. Blood products demand for different procedures and several peri-operative laboratory parameters such as full blood count, and coagulation profile were determined. RESULTS: The greatest demand for blood products was found in valvular surgery and atrial septal defect (ASD) where a mean of four units of red cell concentrate, fresh frozen plasma and cryoprecipitate were transfused. Other surgeries such as, patent ductus arteriosus, Tetralogy of Fallot did not require much transfusion of blood products. Overall, the pre-operative and post-operative haematocrit, white cell count, platelet count, and international normalized ratio (INR) mean were 37% /25%,4.9 X 10 9/L / 11.4 X 10 9/L, 182 X 10 9/L/ 97 X 10 9/L, and 1.15/ 2.2 respectively. CONCLUSION: It appears that transfusion requirement in most open heart surgeries aside from valvular surgery and atrial septal defect (ASD) repair, is minimal. Patients for valvular heart surgeries and ASD repair should be evaluated for possible autologous blood transfusion.


Assuntos
Transfusão de Componentes Sanguíneos/métodos , Transfusão de Componentes Sanguíneos/estatística & dados numéricos , Procedimentos Cirúrgicos Cardíacos , Cardiopatias/cirurgia , Adolescente , Criança , Feminino , Hematócrito , Hospitais de Ensino , Humanos , Coeficiente Internacional Normatizado , Masculino , Nigéria , Contagem de Plaquetas , Complicações Pós-Operatórias , Padrões de Prática Médica , Adulto Jovem
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