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1.
Med Biol Eng Comput ; 58(6): 1159-1175, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32319030

RESUMO

The study and applications of in vivo skin optics have been openly documented as early as the year 1954, or possibly earlier. To date, challenges in analyzing the complexities of this field remain, with wide scopes requiring more scrutiny. Recent advances in spectroscopic research and multivariate analytics allow a closer look into applications potentially for detecting or monitoring diseases. One of the challenges in this field is in establishing a reference for applications which correspond to certain bandwidths. This article reviews the scope on past research on skin spectroscopy, and the clinical aspects which have or may have applications on disease detection or enhancing diagnostics. A summary is supplied on the technicalities surrounding the measurements reported in literature, focused towards the wavelength-dependent applications in themes central to the respective research. Analytics on the topology of the papers' data cited in this work is also provided for a statistical perspective. In short, this paper strives to immediately inform the reader with possible applications via the spectroscopic devices at hand. Graphical Abstract .


Assuntos
Óptica e Fotônica/métodos , Dermatopatias/diagnóstico , Pele/química , Circulação Sanguínea , Eritema/patologia , Humanos , Lactente , Melaninas/química , Melaninas/metabolismo , Monitorização Fisiológica/métodos , Óptica e Fotônica/instrumentação , Oximetria/métodos , Pele/irrigação sanguínea , Espectrometria de Fluorescência , Espectrofotometria Ultravioleta , Espectroscopia de Infravermelho com Transformada de Fourier , Espectroscopia de Luz Próxima ao Infravermelho/métodos , Análise Espectral Raman
2.
Appl Radiat Isot ; 100: 43-9, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25533626

RESUMO

A method for improving the thermoluminescence (TL) yield of silica-based optical fibres is demonstrated. Using silica obtained from a single manufacturer, three forms of pure (undoped) fibre (capillary-, flat-, and photonic crystal fibre (PCF)) and two forms of Ge-doped fibre (capillary- and flat-fibre) were fabricated. The pure fibre samples were exposed to 6 and 21MeV electrons, the doped fibres to 6MV photons. The consistent observation of large TL yield enhancement is strongly suggestive of surface-strain defects generation. For 6MeV irradiations of flat-fibre and PCF, respective TL yields per unit mass of about 12.0 and 17.5 times that of the undoped capillary-fibre have been observed. Similarly, by making a Ge-doped capillary-fibre into flat-fibre, the TL response is found to increase by some 6.0 times. Thus, in addition to TL from the presence of a dopant, the increase in fused surface areas of flat-fibres and PCF is seen to be a further important source of TL. The glow-curves of the undoped fibres have been analysed by computational deconvolution. Trap centre energies have been estimated and compared for the various fibre samples. Two trap centre types observed in capillary-fibre are also observed in flat-fibre and PCF. An additional trap centre in flat-fibre and one further trap centre in PCF are observed when compared to capillary fibre. These elevated-energy trap centres are linked with strain-generated defects in the collapsed regions of the flat fibre and PCF.

3.
Opt Express ; 15(25): 17129-35, 2007 Dec 10.
Artigo em Inglês | MEDLINE | ID: mdl-19551006

RESUMO

Liquid crystal tunable planar Bragg Gratings produced by Direct UV Writing are capable of wavelength tuning of over 100GHz. However, such devices exhibit non-linear tuning curves with threshold points and hysteresis. We show that these effects are due to the formation of disclination structures in the liquid crystal and discuss the role of electrode defects and sample temperature on wavelength tuning.

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