[Results of perftorane local use in complex treatment of patients with odontogenic phlegmons of the face and neck].

Combined treatment of 96 patients with odontogenic phlegmons of the face and neck included local application of perftorane (plasma substitute with gas transport function). The addition of perftorane to complex therapeutic measures provides significant improvement of the patients' general status and speeds up reparative processes in the wound. It facilitates secondary suturing, shortens treatment time, provides wound healing by primary intention, improves functional and cosmetic results.

[Acute musculo-articular disorders in mandibular fractures of different location and methods of their correction]. / Ostrye myshechno-sustavnye narusheniia pri perelomakh nizhnei cheliusti raznoi lokalizatsii i metody ikh korrektsii.

Ninety patients with acute musculo-articular disorders associated with mandibular fractures of different location were examined. Two groups of patients were distinguished, based on the presence of fragments dislocation, soft tissue injuries, and occlusion impairment: 1) 45 patients with mandibular fractures without essential dislocation of fragments and pronounced reaction of soft tissues and 2) 45 patients with notable impairment of soft tissues and dislocation of fragments. Clinical examinations and accessory diagnostic methods after removal of the splints demonstrated the relationship between the severity of musculo-articular disorders and type and location of mandibular fracture; purposeful methods of treatment have been developed.

[Ozone therapy of chronic mandibular osteomyelitis]. / Ozonoterapiia khronicheskikh osteomielitov nizhnei cheliusti.

Clinical picture, bacterial passage, and immune status were studied in patients with chronic traumatic and chronic odontogenic mandibular osteomyelitis. The deepest disorders of biocenosis and the highest incidence of immunodeficiencies were observed in patients with chronic odontogenic osteomyelitis. Local and total ozone therapy is suggested for antibacterial and immunomodulating treatment. Medical ozone exposure promoted more complete and rapid normalization of nonspecific resistance and T-cellular immunity, thus accelerating clinical cure and reducing the incidence of complications.

[Prevention of inflammatory complications after mandibular osteosynthesis by a combination of low-frequency ultrasound and laser exposure]. / Profilaktika vospalitel'nykh oslozhnenii posle operatsii osteosinteza nizhnei cheliusti putem primeneniia sochetannogo vozdeistviia nizkochastotnogo ul'trazvuka i lazera.

Clinical and laboratory study of the efficiency of separate and combined use of low-frequency ultrasound and laser exposure of the operative wound for prevention of pyoinflammatory complications during mandibular osteosynthesis was carried out. Clinical parameters of wound reparation in the course of healing and microbiological and cytological findings in various methods of treatment are presented. The results evidence a high efficiency of these physical methods, particularly of their combination.

[Ozone therapy in treatment of local sluggish suppurative inflammation of maxillofacial soft tissues]. / Kompleksnaia ozonoterapiia ogranichennogo vialotekushchego gnoinogo vospaleniia miagkikh tkanei cheliustno-litsevoi oblasti.

Combined local and general ozone therapy was used in 30 patients with local sluggish pyoinflammatory diseases of the maxillofacial soft tissues. The results were compared to those in 33 patients administered no ozone therapy. Ozone therapy decreased the duration of treatment more than 2-fold due to antibacterial effect and stimulation of nonspecific and immunological reactivity. Lack of obvious contraindications and selective activity and universal immunocorrective effect recommend ozone therapy for wide use in this patient population irrespective of the type of inflammatory reaction.

[Role of phagocytosis activation in the mechanism of therapeutic effect of medical ozone in patients with sluggish purulent inflammations of maxillofacial soft tissues]. / Rol' aktivatsii fagotsitoza v mekhanizme lechebnogo deistviia meditsinskogo ozona u bol'nykh s vialotekushchimi gnoinymi vospalitel'nymi protsessami miagkikh tkanei cheliustno-litsevoi oblasti.

Sixty-three patients with local sluggish suppurative inflammations of maxillofacial soft tissues were examined. Medical ozone was added to the treatment protocols of 30 of these patients. Before treatment peripheral blood leukocyte phagocytic activity was decreased in 54 patients, which corresponded to clinical form of a sluggish inflammation. Traditional therapy did not appreciably change the level of phagocytosis. Addition of medical ozone exposure to therapy promoted normalization of leukocyte phagocytic activity and accelerated liquidation of inflammation.

[The osteoplastic efficacy of different forms of hydroxyapatite based on experimental morphological study data]. / Osteoplasticheskaia éffektivnost' razlichnykh form gidroksiapatita po dannym éksperimental'no-morfologicheskogo issledovaniia.

Time course of healing of induced defects in the femoral bone filled with various forms of hydroxyapatite (HA) was studied in experimental rats on days 30, 60, and 90 after inflicting the defect. HA granulate exerted the best effect on bone repair. In experiments with HA granulate, bone regenerate replaced up to one half of the area of defect by day 90. After insertion of a mixture of granulate and HA powder in bone defects the newly formed bone occupied a little more than one-third of the defect area. In experiments with HA powder suspension the size of bone defect by day 90 was the same as after healing under a blood clot.

[The use of nitatsid and gipozol'-N in the combined treatment of acute inflammatory diseases of the maxillofacial area]. / Primenenie nitatsida i gipozolia-N v kompleksnom lechenii ostrykh vospalitel'nykh zabolevanii cheliustno-litsevoi oblasti.

Combined drugs with a hydrophilic base, nitacide and hyposol-n, were used in combined therapy of acute purulent inflammations of the maxillofacial area. Time course of clinical parameters and changes in microflora were studied in patients administered different local treatments with different inflammatory reactions. The data indicate a high efficiency of the drugs, which optimized local therapy of suppurative wounds and are recommended for wide practical use.

[Dynamics of immune status in patients with phlegmons of the maxillofacial area during endolymphatic antibiotic therapy]]. / Dinamika immunnogo statusa bol'nykh s flegmonami cheliustno-litsevoi oblasti pri éndolimfaticheskoi antibiotikoterapii.

Studies of immunotropic effects of ampicillin, gentamicin sulfate, lincomycin, and rifampicin SV used in endolymphatic therapy of patients with maxillofacial phlegmons demonstrated a pronounced immunomodulating effect of rifampicin SV in polygluquine. The immunomodulating effect of lincomycin was lower, and that of ampicillin virtually null. Gentamicin sulfate suppressed some parameters of the immune status.

[A comparative evaluation of the efficacy of the isolated and joint use of dioksizol and low-frequency ultrasound in the combined treatment of phlegmons of the maxillofacial area]. / Sravnitel'naia otsenka éffektivnosti izolirovannogo i sochetannogo primeneniia dioksizolia i nizkochastotnogo ul'trazvuka v kompleksnom lechenii flegmon cheliustno-litsevoi oblasti.

The effects of dioxycol and low-frequency ultrasound alone and in combinations on the microflora of suppurative wounds formed after opening of maxillofacial phlegmons are assessed in 142 patients. Clinical and laboratory findings indicate a higher efficacy of combined use of these treatment modalities, which are recommended for optimal local treatment of purulent maxillofacial wounds.

[Relationship between nonspecific, immunologic reactivity of the body and the type of course of an acute inflammatory process]. / Sviaz' mezhdu nespetsificheskoi, immunologicheskoi reaktivnost'iu organizma i tipom techeniia ostrogo vospalitel'nogo protsessa.

By using the results of clinical, laboratory, and immunological studies, the authors show that the type (normoergic, hypoergic, hyperergic) of an inflammatory response is related to the parameters of nonspecific and immunological responsiveness of patients with pyo-inflammation in the maxillofacial region. The hypoergic inflammatory response is characterized by the least responsiveness mainly to its cellular link. The hyperergic inflammatory reaction is chiefly caused by considerably enhanced phagocytosis.

[Indications for the use of tactivin in the combined treatment of phlegmons of the maxillofacial area]. / Pokazaniia k primeneniiu taktivina v kompleksnom lechenii flegmon cheliustno-litsevoi oblasti.

The effects of subcutaneous and endolymphatic tactivin (in doses of 1 ml of 0.01% solution daily for 7 days) on clinical and immunological parameters were studied in patients with acute inflammations in the maxillofacial area, running a normo-, hypo-, and hyperergic course. Tactivin accelerated the arrest of inflammatory process and improved the patients' status, particularly so in cases with the hypo- and hyperergic inflammations. The key role in the mechanism of the drug action is played by increase of the immunoregulatory index, which reflects the increasing resistance of the body.