Use of complementary and alternative medicine in HIV-infected subjects.

OBJECTIVES: To compare the characteristics of HIV-infected subjects who had ever used with those who had never used Complementary and Alternative Medicine (CAM). DESIGN: The European Level Epidemiology of Complementary Therapies in HIV project (ELECTHIV 2), a case-control study, was conducted in seven European countries. All HIV-infected subjects who consecutively attended the offices of the collaborating organizations were eligible for this study. Information was obtained from self-administered, anonymous questionnaires. SETTING: A total of 1066 subjects entered the study: 632 were CAM users and 434 had never used CAM. RESULTS: CAM use was more common among females than males (odds ratio (OR) 1.6; 95% confidence interval (CI) 1.2-2.2) and in more educated subjects. CAM use was less common among subjects taking highly active antiretroviral therapy (HAART) (OR 0.5; 95% CI 0.3-0.8), but was more common in outpatients who reported HAART-related side effects (specifically neuropathy). CONCLUSION: This study indicates that CAM use in HIV-infected subjects is related to female gender, higher levels of education and longer duration of HIV infection.

Illicit drug use: can it predict adherence to antiretroviral therapy?

This study analysed the level of adherence to anti-HIV therapies in illegal drug users compared to non-users. Out of 214 patients interviewed. 60 (28%) reported current use of one or more illegal drugs (heroin, cocaine), alcohol (>6 U/day), psychoactive drugs and others. Within the two groups reporting use of heroin and cocaine, the percentage of patients achieving good levels of compliance was higher than among patients who reported not using any substance (50 and 46% vs. 42.3%), among the users of psychoactive pharmaceuticals and alcohol the percentage of high-compliant patients tended to be lower (respectively 26.6 and 30%), but the difference was not significant.

Reasons for complementary therapies and characteristics of users among HIV-infected people.

The aim of this study was to analyse in a large sample of HIV-infected subjects the expectations toward complementary therapies (CT) and the characteristics of users. Self-administered anonymous questionnaires were distributed in seven European countries among HIV-infected subjects consecutively attending the offices of AIDS organizations. Among 632 ever CT users, nutritional supplements (124 subjects) and psycho-physiological approaches (116 subjects) were the most frequent CT used: 61.4% used CT to improve energy. Half the CT users wanted to prevent or alleviate the highly active antiretroviral therapy (HAART) side effects. General malaise and neuropathy were the most common HAART side effects, where CT users found improvement (62.0% and 54.7%, respectively). Acupuncture improved neuropathy in a high proportion of subjects (87.5%); whereas for others CT were considered less effective (range 20.0-36.4%). The most common expectations from CT were to improve energy and to prevent or alleviate the HAART side effects. This suggests that HIV-infected people expect not so much specific help as general support from CT.