Surto de Trichophyton equinum var. equinum em eqüinos no sul do Brasil / Outbreak of Trichophyton equinum var. equinum in horses in the south of Brazil

Descreve-se, neste trabalho, um surto de dermatofitose eqüina no Sul do Brasil. Cinqüenta e oito animais jovens (55,2 por cento) apresentavam lesões clínicas características da enfermidade. O diagnóstico micológico realizado pela presença do fungo nos pêlos, associado às características macro e micromorfológicas das colônias isoladas em meio de cultivo, permitiram a classificação do dermatófito como Trichophyton equinum var. equinum.

One outbreak of dermatophytosis in horses is described in south Brazil. Fifty eight young animals (55.2 percent) presented clinical signs of the disease. The mycological diagnosis was realized through the presence of fungus in the hair, associated with the macro and micromorphologic characteristics of the isolated colonies in agar also allowed the dermatophyte´s classification as Trichophyton equinum var. equinum.

Dermatophytes isolated from dogs and cats suspected of dermatophytosis in Southern Brazil

Dermatophytosis which is characterized by a superficial infection confined to keratinised tissues, is the most common fungal disease in small animal veterinary medicine. It is unreliable to diagnose dermatophytosis on the basis of clinical signs alone, not only for the variable nature of the dermatological findings but also because there are several other skin diseases which mimic the typical fungal lesion (circular lesions with alopecia). The present study reports laboratory results of an extensive survey evaluating fungal and parasitic aetiology of skin diseases through the analysis of 1,240 fur, nails and skin scraping specimens from dogs and cats with clinical suspicion of dermatophytosis. Samples collected in several veterinary clinics of the Santa Catarina, Paraná and Rio Grande d o Sul states, mainly of the Santa Maria city in Rio Grande do Sul, were processed at the Mycology Research Laboratory of the Federal University of Santa Maria, Southern Brazil, between 1998 and 2003. Among canine and feline samples, the percentages of positive dermatophyte specimens were 10.2% and 27.8%, respectively. The most prevalent fungal specie in both cats and dogs was Microsporum canis, which was isolated in 68.5% of the positive cultures for dermatophytes in dogs samples, being the only species recovered from cats cultures. Malassezia pachydermatis was the most commonly isolated yeast

Dermatophytes isolated from dogs and cats suspected of dermatophytosis in Southern Brazil

Dermatophytosis which is characterized by a superficial infection confined to keratinised tissues, is the most common fungal disease in small animal veterinary medicine. It is unreliable to diagnose dermatophytosis on the basis of clinical signs alone, not only for the variable nature of the dermatological findings but also because there are several other skin diseases which mimic the typical fungal lesion (circular lesions with alopecia). The present study reports laboratory results of an extensive survey evaluating fungal and parasitic aetiology of skin diseases through the analysis of 1,240 fur, nails and skin scraping specimens from dogs and cats with clinical suspicion of dermatophytosis. Samples collected in several veterinary clinics of the Santa Catarina, Paraná and Rio Grande d o Sul states, mainly of the Santa Maria city in Rio Grande do Sul, were processed at the Mycology Research Laboratory of the Federal University of Santa Maria, Southern Brazil, between 1998 and 2003. Among canine and feline samples, the percentages of positive dermatophyte specimens were 10.2% and 27.8%, respectively. The most prevalent fungal specie in both cats and dogs was Microsporum canis, which was isolated in 68.5% of the positive cultures for dermatophytes in dogs samples, being the only species recovered from cats cultures. Malassezia pachydermatis was the most commonly isolated yeast

Dermatophytes isolated from dogs and cats suspected of dermatophytosis in Southern Brazil

Dermatophytosis which is characterized by a superficial infection confined to keratinised tissues, is the most common fungal disease in small animal veterinary medicine. It is unreliable to diagnose dermatophytosis on the basis of clinical signs alone, not only for the variable nature of the dermatological findings but also because there are several other skin diseases which mimic the typical fungal lesion (circular lesions with alopecia). The present study reports laboratory results of an extensive survey evaluating fungal and parasitic aetiology of skin diseases through the analysis of 1,240 fur, nails and skin scraping specimens from dogs and cats with clinical suspicion of dermatophytosis. Samples collected in several veterinary clinics of the Santa Catarina, Paraná and Rio Grande d o Sul states, mainly of the Santa Maria city in Rio Grande do Sul, were processed at the Mycology Research Laboratory of the Federal University of Santa Maria, Southern Brazil, between 1998 and 2003. Among canine and feline samples, the percentages of positive dermatophyte specimens were 10.2% and 27.8%, respectively. The most prevalent fungal specie in both cats and dogs was Microsporum canis, which was isolated in 68.5% of the positive cultures for dermatophytes in dogs samples, being the only species recovered from cats cultures. Malassezia pachydermatis was the most commonly isolated yeast

Surto de Trichophyton equinum var. equinum em eqüinos no sul do Brasil

One outbreak of dermatophytosis in horses is described in south Brazil. Fifty eight young animals (55.2%) presented clinical signs of the disease. The mycological diagnosis was realized through the presence of fungus in the hair, associated with the macro and micromorphologic characteristics of the isolated colonies in agar also allowed the dermatophyte´s classification as Trichophyton equinum var. equinum.

Descreve-se, neste trabalho, um surto de dermatofitose eqüina no Sul do Brasil. Cinqüenta e oito animais jovens (55,2%) apresentavam lesões clínicas características da enfermidade. O diagnóstico micológico realizado pela presença do fungo nos pêlos, associado às características macro e micromorfológicas das colônias isoladas em meio de cultivo, permitiram a classificação do dermatófito como Trichophyton equinum var. equinum.

Surto de Trichophyton equinum var. equinum em eqüinos no sul do Brasil

One outbreak of dermatophytosis in horses is described in south Brazil. Fifty eight young animals (55.2%) presented clinical signs of the disease. The mycological diagnosis was realized through the presence of fungus in the hair, associated with the macro and micromorphologic characteristics of the isolated colonies in agar also allowed the dermatophyte´s classification as Trichophyton equinum var. equinum.

Descreve-se, neste trabalho, um surto de dermatofitose eqüina no Sul do Brasil. Cinqüenta e oito animais jovens (55,2%) apresentavam lesões clínicas características da enfermidade. O diagnóstico micológico realizado pela presença do fungo nos pêlos, associado às características macro e micromorfológicas das colônias isoladas em meio de cultivo, permitiram a classificação do dermatófito como Trichophyton equinum var. equinum.

Synthesis and antibiotic activity of some -Carboline alkaloids

Nine -carboline alkaloids were synthetized and screened for antibiotic activity. Six of the compounds testes showed inhibitory activity against one or more of the microorganisms assayed.

Nove alcalóides -carbolinicos foram sintetizados e avaliados quanto à sua ação antibíotica. Seis dos compostos inibiram o crescimento de um ou mais dos microorganismos ensaiados.

Synthesis and antibiotic activity of some -Carboline alkaloids

Nine -carboline alkaloids were synthetized and screened for antibiotic activity. Six of the compounds testes showed inhibitory activity against one or more of the microorganisms assayed.

Nove alcalóides -carbolinicos foram sintetizados e avaliados quanto à sua ação antibíotica. Seis dos compostos inibiram o crescimento de um ou mais dos microorganismos ensaiados.