RESUMO
Intestinal lymphangiectasia is a very rare pathology, characterized by the presence of enlarged lymphatic vessels in all layers of the intestinal wall and in the mesentery. As a result, "lymphatic lakes" are formed, through which lymph exudates into the lumen of the intestine. The main manifestation is hypoproteinemic edema. Diagnosis of the disease is based on laboratory-instrumental methods of investigation, including by determining in the stool α-1 antitrypsin as a screening test. Treatment includes: a diet rich in calcium, trace elements, be sure to use medicinal foods enriched with medium chain triglycerides, substitution and symptomatic therapy.
Assuntos
Linfangiectasia Intestinal , Edema , Trato Gastrointestinal , Humanos , Linfangiectasia Intestinal/diagnóstico , Linfangiectasia Intestinal/terapia , Triglicerídeos , alfa 1-Antitripsina/análiseRESUMO
The objective of the present work was to analyze the current concept of the genetically predetermined condition Zivert-Kartagener's syndrome with special reference to the pathogenetic mechanisms underlying the development of this condition, its clinical picture and methods of treatment. The authors' original observations of the patients presenting with Zivert-Kartagener's syndrome are reported.
Assuntos
Dextrocardia/diagnóstico por imagem , Infertilidade , Síndrome de Kartagener , Depuração Mucociliar/genética , Rinite , Sinusite , Doença Crônica , Gerenciamento Clínico , Dineínas/genética , Feminino , Humanos , Infertilidade/diagnóstico , Infertilidade/etiologia , Síndrome de Kartagener/diagnóstico , Síndrome de Kartagener/fisiopatologia , Síndrome de Kartagener/terapia , Mutação , Prognóstico , Rinite/diagnóstico , Rinite/etiologia , Rinite/fisiopatologia , Rinite/terapia , Sinusite/diagnóstico , Sinusite/etiologia , Sinusite/fisiopatologia , Sinusite/terapia , Supuração/fisiopatologia , Adulto JovemRESUMO
The authors present the currently available data on mucoviscidosis (cystic fibrosis) based on their original experience and the review of the relevant literature. Special attention is given to the pathogenetic mechanisms underlying the development of this condition, its diagnostics, and methods of treatment as exemplified by the clinical case of cystic fibrosis in an adult patient.
Assuntos
Antibacterianos/uso terapêutico , Fibrose Cística , Insuficiência Pancreática Exócrina , Pseudomonas aeruginosa , Medicamentos para o Sistema Respiratório/uso terapêutico , Infecções Respiratórias , Adulto , Broncoscopia/métodos , Fibrose Cística/diagnóstico , Fibrose Cística/etiologia , Fibrose Cística/fisiopatologia , Fibrose Cística/terapia , Regulador de Condutância Transmembrana em Fibrose Cística/genética , Gerenciamento Clínico , Insuficiência Pancreática Exócrina/diagnóstico , Insuficiência Pancreática Exócrina/fisiopatologia , Insuficiência Pancreática Exócrina/terapia , Humanos , Masculino , Testes de Sensibilidade Microbiana/métodos , Mutação , Pseudomonas aeruginosa/efeitos dos fármacos , Pseudomonas aeruginosa/isolamento & purificação , Infecções Respiratórias/diagnóstico , Infecções Respiratórias/tratamento farmacológico , Infecções Respiratórias/microbiologia , Resultado do TratamentoRESUMO
Tuberculous lesions of the liver frequently occur in autopsy material, even though most of them are clinically unapparent. Pathogenetically, hepatic tuberculosis is a manifestation of general military tuberculosis with the infection brought in through the hematogenous route (through the hepatic artery or the portal system) as a result of intestinal or mesenteric lymph node tuberculosis. We report a case of combination of hepatic tuberculosis and diabetes mellitus in a young woman with reference to the clinical course of the disease, its diagnostics and treatment.
Assuntos
Antituberculosos/administração & dosagem , Fígado Gorduroso , Fígado , Mycobacterium tuberculosis/isolamento & purificação , Tuberculose Hepática , Biópsia/métodos , Fígado Gorduroso/diagnóstico , Fígado Gorduroso/etiologia , Fígado Gorduroso/fisiopatologia , Feminino , Humanos , Fígado/diagnóstico por imagem , Fígado/microbiologia , Fígado/patologia , Cirrose Hepática/diagnóstico , Cirrose Hepática/etiologia , Cirrose Hepática/fisiopatologia , Testes de Função Hepática/métodos , Pessoa de Meia-Idade , Tomografia Computadorizada Espiral/métodos , Resultado do Tratamento , Tuberculose Hepática/complicações , Tuberculose Hepática/diagnóstico , Tuberculose Hepática/terapiaRESUMO
The article describes Rossolimo-Melkersson-Rosenthal disease (RMRD); historical background and the modern concept of its pathogenesis are presented in brief. The clinical picture of the disease is described in more detail; the variants of the course of the disease and the manifestations of the monosymptomatic, bisymptomatic, and triadic variants are presented. The article contains a clinical observation of a female patient aged 38, whose first symptoms developed at the age of 18 as facial neuritis and left mimic musculature paresis. With time, the patient developed all the three characteristic components of RMRD.