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1.
Dermatol Res Pract ; 2024: 8589329, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38715735

RESUMO

Introduction: The purpose of this study was to study the quality of life and psychiatric comorbidities of subjects practicing voluntary skin depigmentation in the city of Cotonou. Methods: A cross-sectional, prospective, and analytical study, based on a three-stage probabilistic sampling method, included from June to October 2020, consenting subjects over 15 years of age, practicing artificial skin depigmentation, and residing for at least one year in Cotonou. The Dermatology Life Quality Index, Rosenberg, and Hospital Anxiety and Depression scales allowed us to evaluate the quality of life and self-esteem, and identify anxiety and depression, respectively. A p value <0.05 indicated a significant result. Results: We included 330 subjects. The mean age was 33.6 ± 11.6 years and the sex ratio was 0.4. Impaired quality of life was observed in 93.7% of subjects. Anxiety was diagnosed in 11.2% and depression in 5.8% of them. Self-esteem was low or very low in 24.2%. The degree of quality of life and the alteration of self-esteem, and the frequency of anxiety and depression were proportional to the number of skin lesions, the lightening products used, and the monthly cost of the products. Conclusion: The use of several lightening products exposes patients to numerous skin lesions, which are a source of impaired quality of life and whose persistence leads to psychiatric comorbidities.

2.
West Afr J Med ; 39(5): 538-542, 2022 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-35633648

RESUMO

BACKGROUND: The aim of this study was to describe the epidemiological, clinical and etiological aspects of severe cutaneous adverse drug reactions in children in dermatologyvenereology unit at National and Teaching Hospital of Cotonou. METHODS: A retrospective and descriptive study was carried out for 10 years in dermatology-venereology unit at the National and Teaching Hospital of Cotonou to document the epidemiological, clinical and etiological aspects of severe cutaneous adverse drug reactions in children. It included all children aged from 0 to 18 years with clinical diagnosis of severe cutaneous adverse drug reactions. Drug imputability was based on the criteria of the French pharmacovigilance group. RESULTS: Severe cutaneous adverse drug reactions accounted for 47.3% of paediatric cases (35/74 cases). The mean age was 9.3 years ± 5.2. The sex-ratio was 1.1. Self-medication was noted in 76.5% of children, on the initiative of parents in 66.7% of cases. There were 51.4% cases of Steven Johnson syndrome, 22.8% cases of Lyell syndrome, 8.5% cases of generalized and bullous fixed drug eruption, 2.9% cases of acute generalized exanthematous pustulosis and erythrodermic maculo-papular rash. Drug combinations was noted in 20% of cases. Penicillins (26.5%), paracetamol and sulfonamides (16.3%) were the drugs frequently incriminated. CONCLUSION: Steven Johnson syndrome and Lyell syndrome were the main severe cutaneous adverse drug reactions in children, mostly of school age. Penicillins, paracetamol and sulfonamides were the drugs frequently used and administered most often on self-medication.


INTRODUCTION: L'objectif de cette étude était de décrire les aspects épidémiologiques, cliniques et étiologiques des toxidermies graves chez les enfants en dermatologie à Cotonou. METHODES: Une étude rétrospective et descriptive a été réalisée sur 10 ans dans le service de dermatologie du Centre National Hospitalier et Universitaire de Cotonou pour documenter les aspects épidémiologiques, cliniques et étiologiques des toxidermies graves chez les enfants. Étaient inclus tous les enfants âgés de 0-18 ans chez qui le diagnostic clinique de toxidermie grave a été retenu. L'imputabilité médicamenteuse était basée sur les critères du groupe français de pharmacovigilance. RESULTATS: Les toxidermies graves représentaient 47,3% des cas pédiatriques (35/74 cas). L'âge moyen était de 9,3 ans ± 5,2. La sex-ratio H/F était de 1,1. Une automédication a été notée chez 76,5% des enfants, sur l'initiative des parents dans 66,7% des cas. Il y avait 51,4% de cas de syndrome de Steven Johnson, 22,8% de cas de syndrome de Lyell, 8,5% de cas d'érythème pigmenté fixe bulleux étendu, 2,9% de pustulose exanthématique aigüe généralisée et d'exanthème maculo-papuleux eìrythrodermique. Une polymédication a été notée dans 20% des cas. Les pénicillines (26,5%), le paracétamol et les sulfamides (16,3%) étaient les médicaments fréquemment incriminés. CONCLUSION: Le syndrome de Steven Johnson et le syndrome de Lyell étaient les principales toxidermies graves chez les enfants, majoritairement en âge scolaire. Les pénicillines, le paracétamol et les sulfamides étaient les médicaments fréquemment incriminés et administrés le plus souvent en automédication. Mots clés: Toxidermies graves, syndrome de Steven Johnson, syndrome de Lyell, automédication, sulfamides, enfants, Benin.


Assuntos
Dermatologia , Síndrome de Stevens-Johnson , Venereologia , Acetaminofen , Antibacterianos , Anti-Inflamatórios não Esteroides/efeitos adversos , Benin , Criança , Hospitais de Ensino , Humanos , Penicilinas , Estudos Retrospectivos , Síndrome de Stevens-Johnson/epidemiologia , Síndrome de Stevens-Johnson/etiologia , Sulfonamidas
3.
Journal de la société de Biologie Clinique ; (38): 16-18, 2021. figures, tables
Artigo em Francês | AIM (África) | ID: biblio-1359865

RESUMO

Le pityriasis versicolor (PV) est une pathologie cutanée fréquemment rencontrée en consultation dermatologique, surtout dans les pays à climat tropical. Une étude épidémio-clinique, s'intéressant aussi aux comorbidités associées et au retentissement de la maladie a été réalisée. Elle a concerné 118 patients venus consulter dans le service de Dermatologie-Vénérologie au Centre Hospitalier Universitaire Départemental Borgou-Alibori, Bénin. La population la plus touchée était les sujets jeunes avec une fréquence plus élevée chez les 20-30 ans (38,98%). L'âge moyen était de 27,03 ans avec une sex ratio à 1,40. Les antécédents familiaux de pityriasis versicolor ont été retrouvés chez 10 patients soit 8,47%. Comme facteurs favorisants, 57,62% utilisaient les laits corporels dépigmentants. La forme classique (20,37%) était majoritairement représentée. L'acné a été notée chez 19 patients (16,10%). La sérologie VIH était revenue positive chez 4 patients (5,55%) et le diabète a été diagnostiqué chez 3 patients (7,5%). Une altération de la qualité de vie des sujets (35,59%) a été retrouvée.


Pityriasis versicolor (PV) is a cutaneous pathology frequently encountered in dermatological consultations, especially in countries with a tropical climate. An epidemio-clinical study, also questioning the associated comorbidities and the repercussions of the disease, was carried out on 118 patients who came to the Dermatology-Venerology Department at the Borgou-Alibori Departmental University Hospital, Benin. The most affected population was young subjects with a higher frequency in the 20-30 years old (38.98%). The mean age was 27.03 years with a sex ratio of 1.40. Family history was found in 10 patients (8.47%). As contributing factors, 57.62% used depigmenting body milks. The classic form (20.37%) was predominantly represented. Acne was noted in 19 patients (16.10%). HIV serology was positive in 4 patients (5.55%) and diabetes was dignosed in 3 patients (7.5%). A slight alteration in the quality of life of the subjects (35.59%) was found.


Assuntos
Humanos , Masculino , Feminino , Qualidade de Vida , Sinais e Sintomas , Tinha Versicolor , Epidemiologia , Infecções por HIV
4.
Med Sante Trop ; 29(4): 402-408, 2019 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-31884995

RESUMO

The objective of our study was to evaluate the medico-surgical management of Buruli ulcer (BU) in the BU Screening and Treatment Center (CDTUB) of Allada in Benin. This retrospective and descriptive study retrospectively reviewed records of patients seen from 2010 to 2014 at the CDTUB of Allada. It included patients diagnosed with BU according to WHO epidemiological and clinical criteria as well as laboratory results and who were treated according to WHO medical and surgical recommendations. In all, 274 patients were diagnosed and treated, 57.7% of them children younger than 15 years. Ulcerative lesions (189, 69%) and WHO category II lesions (144, 52.5%) predominated. All patients received dual antibiotic therapy and 43.4% (119) underwent surgery as well. Category III lesions and multifocal lesions required more surgery, whereas most category I lesions healed under medical treatment. The overall rate of healing was 92%: 53.3% for patients who received only antibiotic therapy and 38.7% for those who also had surgery. The median healing time was 13 weeks and ranged from 4 to 56 weeks. In the CDTUB of Allada, between 2010 and 2014, most patients were treated with antibiotic therapy alone, but a significant number still received surgery.


Assuntos
Antibacterianos/uso terapêutico , Úlcera de Buruli/tratamento farmacológico , Úlcera de Buruli/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Benin , Criança , Pré-Escolar , Terapia Combinada , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Tempo , Adulto Jovem
5.
Bull Soc Pathol Exot ; 112(4): 190-194, 2019.
Artigo em Francês | MEDLINE | ID: mdl-32003196

RESUMO

Hookworm-related cutaneous larva migrans is caused by the subcutaneous migration of hookworm larvae. The characteristic sign is a serpiginous cutaneous track. Folliculitis is an uncommon clinical manifestation. We report a case of hookworm-related folliculitis in a woman performing skin bleaching. A 33-year-old woman presented with a widespread cutaneous eruption made of erythematous and itchy follicular papulo-nodules, with erythematous serpiginous tracks, about 5-10cm long and numerous streaks of scratching, located on the limbs, buttocks and trunk. The cutaneous lesions occurred two days after contact with the floor of a warehouse contamined by faeces of cats. The lesions have been evolving for a week and have been treated with antibiotics without success. Clinical examination found cutaneous atrophy, purple stretch marks and hyperpigmentation of dorsal parts of fingers joints. The patient reported having been using bleaching cosmetics containing topical steroids and hydroquinone for twelve years. She was cured within 4 weeks with oral albendazole 400mg per day during 7 consecutive days.


La folliculite ankylostomienne est une forme folliculaire de larva migrans cutanée ankylostomienne rarement observée. Nous en rapportons un cas chez une patiente de 33 ans, se dépigmentant depuis 12 ans. Elle a consulté pour une éruption évoluant depuis une semaine, diffuse, très prurigineuse, apparue deux jours après le contact avec le sol d'un entrepôt souillé par des déjections de chats. L'examen physique retrouvait de nombreuses lésions de folliculites, érythémateuses coexistant avec des cordons serpigineux de dermatite rampante sur les zones d'extension des membres, le dos, les fesses et l'abdomen, typiques de folliculite ankylostomienne. Un traitement à base d'albendazole 400 mg par jour pendant 7 jours a permis d'obtenir la guérison.


Assuntos
Ancylostomatoidea , Foliculite/parasitologia , Larva Migrans/diagnóstico , Preparações Clareadoras de Pele , Adulto , Albendazol/uso terapêutico , Animais , Anti-Helmínticos , Benin , Gatos , Fezes/parasitologia , Feminino , Humanos , Larva Migrans/tratamento farmacológico , Larva Migrans/etiologia
6.
Artigo em Francês | AIM (África) | ID: biblio-1264174

RESUMO

Introduction : Les mycoses superficielles sont fréquentes en zones tropicales et représentent le premier motif de consultation en dermatologie dans de nombreux pays africains. Matériel et méthodes : Une étude rétrospective, descriptive et analytique a été réalisée dans le service de Dermatologie du Centre National Hospitalier et Universitaire de Cotonou pour décrire le profil épidémiologique et clinique des mycoses superficielles. Elle a inclus sur 10 ans tous les patients chez qui un diagnostic clinique de mycose superficielle a été retenu. Résultats : La prévalence des mycoses superficielles était de 9,6% (1037/10787 patients). Les deux sexes étaient uniformément représentés et l'âge moyen était de 32,2 ans. Trois groupes cliniques de mycoses superficielles étaient retrouvés : dermatophytoses (44,7%), candidoses cutanéo-muqueuses (32,8%) et pityriasis versicolor (31,3%). Les épidermomycoses (93,4%) étaient réparties en dermatophytoses de la peau glabre et des plis (36,4%), pityriasis versicolor (31,3%) et candidoses des plis (25,7%). Les onychomycoses (9,7%) étaient soit de suspicion candidosique (6,4%) ou soit dermatophytique (3,3%). Les teignes représentaient 5% de l'ensemble des mycoses superficielles et la candidose muqueuse 0,7%. Les principaux facteurs favorisants identifiés étaient l'utilisation abusive des savons antiseptiques (20,4%) et l'usage à visée cosmétique de produits dépigmentants (12,7%). Conclusion : Les mycoses superficielles étaient fréquentes avec une prédominance des épidermomycoses dans le service de dermatologie de Cotonou. Les habitudes cosmétiques représentaient un important facteur favorisant de ces épidermomycoses


Assuntos
Benin , Micoses , Tinha , Tinha Versicolor
7.
Artigo em Francês | AIM (África) | ID: biblio-1264200

RESUMO

L'objectif de cette étude était de documenter les aspects épidémiologiques et cliniques du zona en milieu hospitalier à Cotonou. Matériel et méthodes : L'étude était rétrospective et descriptive sur 10 ans et a concerné tous les nouveaux patients reçus en consultation dans le service de Dermatologie du Centre National Hospitalier et Universitaire de Cotonou (CNHU-C), chez qui le diagnostic clinique de zona a été retenu. Résultats : Sur les 10787 nouveaux patients reçus durant la période, 70 présentaient un zona correspondant à une prévalence de 0,6%. Le sex-ratio H/F était de 1,1. La moyenne d'âge était de 42,3 ans avec des extrêmes de 1 an et 73 ans. La tranche d'âge la plus touchée était celle des patients de 50-60 ans. L'infection à VIH était associée au zona dans 46,9% des cas. Les formes érythémato-vésiculeuses à disposition unilatérale étaient prédominantes (79%). Les formes nécrotiques (10%) et nécrotico-hémorragiques (4%) étaient l'apanage des patients infectés par le VIH. Conclusion : Le zona était une dermatose rare dans le service de dermatologie du CNHU- C. L'immunodéficience par le VIH et l'immunosénescence étaient les principaux facteurs de co-morbidité


Assuntos
HIV , Benin , Herpes Zoster , Imunossenescência
8.
Artigo em Francês | AIM (África) | ID: biblio-1264142

RESUMO

Nous rapportons ici un cas de condylome géant vulvaire chez un nourrisson de 02 ans contaminé par sa « baby-sitter » qui présentait les mêmes lésions. Traité par exérèse chirurgicale couplée à une électrocoagulation, l'évolution a été marquée par une récidive deux semaines après le traitement ; ce qui a nécessité une deuxième séance d'électrocoagulation. Plus d'un an après, plus aucune lésion n'a été notée témoignant ainsi d'un succès thérapeutique. La non disponibilité de l'imiquimod dans notre zone géographique, impose un recours systématique à un traitement invasif quelque soit l'âge du patient


Assuntos
África Ocidental , Benin , Eletrocoagulação , Lactente
9.
Med Sante Trop ; 24(4): 416-9, 2014.
Artigo em Francês | MEDLINE | ID: mdl-25499900

RESUMO

OBJECTIVE: The aim of this study was to document the epidemiological and clinical characteristics of anogenital dermatoses (AGDs) in Cotonou, Benin. METHOD: This retrospective, descriptive study, conducted in the Department of Dermatology-Venereology at the National University Hospital of Cotonou, examined medical records of admissions and outpatient consultations for the 5-year period 2005-2009 and included the records of all patients with a clinical diagnosis of AGD. RESULTS: The prevalence of AGD in our series was 2.6% and the prevalence of sexually transmitted AGDs (STIs) was 1.3%. The sex ratio (M:F) was 2.5, and the patients' average age was 31.1 years. AGDs were classified as infectious (77%), inflammatory (12.6%), non-infectious tumors (3.7%), physiological (2.1%), psychodermatoses (2.1%), non-infectious ulcers (1.6%), and dyschromia (1%). STIs accounted for 44% of the AGDs: condyloma (65.5%), genital herpes (19%), urethritis (8.3%), and chancroids (4.8%). The primary sites in men were the foreskin, the groin, the scrotum, and the glans, and in women, the labia majora, the groin, the labia minora, and the anal cleft. CONCLUSION: AGDs were relatively rare in hospital consultations in Cotonou. They were mainly infectious (viral or fungal), and nearly half were STIs.


Assuntos
Infecções Sexualmente Transmissíveis/diagnóstico , Infecções Sexualmente Transmissíveis/epidemiologia , Dermatopatias/diagnóstico , Dermatopatias/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Canal Anal , Benin/epidemiologia , Feminino , Genitália , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Adulto Jovem
10.
Bull Soc Pathol Exot ; 107(3): 139-41, 2014 Aug.
Artigo em Francês | MEDLINE | ID: mdl-24792459

RESUMO

Balanitis of Zoon (BZ) characterized by an important plasma cell infiltration occurs exclusively in uncircumcised men aged between 40-80 years. We report here a case of BZ in an HIV infected patient who was circumcised since birth. A 43-year old man consulted in 2009 for itchy and not painful glans erosion evolving for one year. He is HIV1 infected and has been under didanosine, lamiduvine and nelfinavir for three years. Under this treatment, his CD4 count increased from 26 cells/mm(3) in 2007 to 206 cells/mm(3) at the time of the consultation. We noted after examination clean burgeoning erosion, red in places, pink in other places, with fuzzy boundary, sitting on the glans and extending into the preputial sulcus. Histopathology showed infiltration by sheets of plasma cells with perivascular topography in the dermis. The bacterial cultures and syphilis serology were negative. We noted a good outcome after four weeks of application of 3% oxytetracycline ointment. This observation suggests that the BZ can occur on a HIV infected patient whether he was circumcised or not. Thus, it appears fair to think of BZ faced with a chronic erosion of the glans in HIV infected patient.


Assuntos
Balanite (Inflamação)/complicações , Infecções por HIV/complicações , Adulto , Balanite (Inflamação)/diagnóstico , Benin , Circuncisão Masculina , Infecções por HIV/diagnóstico , HIV-1 , Humanos , Masculino
11.
Med Sante Trop ; 22(3): 287-91, 2012.
Artigo em Francês | MEDLINE | ID: mdl-23253661

RESUMO

INTRODUCTION: Keloids are abnormal growths of fibrous tissue often seen on dark skin. We studied their clinical, epidemiological and therapeutic aspects in 456 consecutive cases. PATIENTS AND METHODS: This retrospective study covering a 20-year period describes and analyzes all patients seen for keloids during that period. RESULTS: The age range of 15-24 year-olds was affected most often (35.72%), and the male/female sex ratio was 0.66. Pruritus was the most frequent symptom (72.23%). The zones at high risk for keloids were: the trunk (chest and abdominal area) (39.57%) and the face (10.65%).The most frequent causes were various sorts of trauma (75%), in descending order of frequency: cutaneous infections, surgical trauma, ulcerating lesions, and burns. The existence of spontaneous keloids remains controversial. Steroid infiltration used alone or with other medication remains the first-line treatment in our study. DISCUSSION: Our study confirms the high frequency of keloids in dark skin, especially females. The trunk and face are zones at high risk for keloid formation. CONCLUSION: An underlying trauma must always be sought for keloids on dark skin.


Assuntos
População Negra , Queloide , Adolescente , Feminino , Humanos , Queloide/diagnóstico , Queloide/epidemiologia , Queloide/terapia , Masculino , Estudos Retrospectivos , Adulto Jovem
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