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BMJ Case Rep ; 20162016 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-26969360

RESUMO

Glioblastoma multiforme (GBM) is a high-grade primary brain tumour with a notably poor prognosis. Research demonstrates a median survival of just over 1 year following aggressive treatment. Long-term survival is notably rare. Cranial radiotherapy and postexcisional prophylactic treatment is associated with the development of second, histologically distinct tumours in rare cases. Radiation-induced intracranial schwannomas are uncommon, with only a small number of cranial nerve schwannoma cases reported in recent decades. To our knowledge, this is the first reported case of a radiation-induced benign trigeminal schwannoma occurring following long-term survival from glioblastoma. Here we present (1) a rare case of 14-year survival following treatment of a right parietal glioblastoma and the development of a radiation-induced benign trigeminal schwannoma in a 35-year-old man, and (2) a review of radiation-induced schwannoma cases reported in the existing literature.


Assuntos
Neoplasias Encefálicas/etiologia , Neoplasias dos Nervos Cranianos/etiologia , Glioblastoma/radioterapia , Neoplasias Induzidas por Radiação/diagnóstico , Neurilemoma/etiologia , Doenças do Nervo Trigêmeo/etiologia , Adulto , Neoplasias Encefálicas/diagnóstico , Neoplasias dos Nervos Cranianos/diagnóstico , Humanos , Masculino , Neurilemoma/diagnóstico , Sobreviventes , Doenças do Nervo Trigêmeo/diagnóstico
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