RESUMO
Thyroid-like follicular carcinoma of the kidney (TLFCK) is a rare cancer that emerged to the medical literature only a few years ago. We present here the first case of thyroid follicular carcinoma-like renal tumor from Syria. The case presented symptomatically and was managed in our surgical unit. Generally, the presenting age described for the previous cases was 19-60 (mean 39.5) with only three cases with younger ages. Here in our case, the patient is only 13 years old making this only the fourth case worldwide of TLFCK in a child. The microscopic view of the tumor showed distinct thyroid features. In addition the immunohistochemical stains played the definitive role in the diagnosis. The staining for Vimentin, and CK19 were diffusively positive. CK7 was focally positive, whereas TTf1, Thyroglobulin, WT1, CD10 and EMA were negative. It is important to consider this diagnosis to spare the patient the treatment protocol of primary thyroid cancer with metastasis.
RESUMO
Primitive neuroectodermal tumor (PNET) mainly arises from soft tissues of the extremities such as humerus, femur, C tibia. It rarely arises from kidney; less than 200 cases have been reported in the literature. The clinical presentation and radiography findings are not specific. Here we first report two cases of renal primitive neuroectodermal tumor in Syria. the first patient was 26-year-old- female that presented to urology clinic complaining of right flank pain. Ultrasonography of the abdomen showed a large mixed heterogeneous mass in the right kidney with no hemorrhage or calcification and MSCT of abdomen and pelvis demonstrate a mixed well-demarcated heterogeneous mass measuring (74*117) mm in the right kidney right radical nephrectomy was performed. The second patient 19-year-old-male presented with left flank pain. Ultrasonography of the abdomen showed mixed large mass involving the left kidney, with unmarked border. The CT of the abdomen and pelvis demonstrating a (30*110*90) mm left renal mass and periaortic lymphadenopathy measuring (45*28) mm. The patient underwent Left radical nephrectomy with periaortic lymphadenectomy dissection. The final diagnosis for both cases was Renal PNET based on microscopic and immunohistochemistry examination. In patient with suspected renal mass in the radiographic images, the diagnosis of renal primitive neuroectodermal tumor should be kept in the mind despite its rarity. The final diagnosis is done by histopathological study in association with immunohistochemical examination.
RESUMO
BACKGROUND: Seminoma is the most common subtype of testicular cancer and occurs most commonly in patients aged 30-49 years, but decreases to a very low level in men in their 60s or older. CASE PRESENTATION: A 90-year-old Syrian man with a 6-year history of an increase in size of his right scrotum, presented to the urological clinic and, on clinical examination, the findings suggested testicular tumor. After orchiectomy and histology results based on microscopic and immunohistochemical examinations, a pure seminoma was diagnosed, so we describe in this case report the second-oldest patient with classical seminoma in the medical literature. CONCLUSION: This case report has been written to focus on the probability of any type of testicular tumor occurring at any age or decade; urologists should consider seminoma as a differential diagnosis with any testicular swelling even in elderly patients.
