RESUMO
Adenoid cystic carcinoma (ACC) represents approximately 10% of all epithelial salivary neoplasms and most commonly involves the parotid gland. We report CT and MRI finding of a 38-year-old young man presented to our ENT department with 02 years history of an external auditory canal stenosis. Physical examination revealed bilateral parotid gland swelling with a complete stenosis of the left external auditory canal. Temporal bone contrast enhanced CT-SCAN revealed is an isodense enhancing mass measuring 4 cm involving posterior and inferior external auditory canal wall, and invading the superficial lobe of the homolateral parotid gland. No bone erosion was noted. MRI investigation has shown a tumor process highly suspicious of malignancy centered on the left EAC involving the superficial lobe of the homolateral parotid gland. Adenoid cystic carcinoma (ACC) of the parotid gland was the final diagnosis, after surgical biopsy and histopathological examination. The Pre-operative check-up demonstrated multiple round shape lung lesions suggestive of multiple metastases. Considering the metastatic stage of the tumor, a collegial decision to adopt a palliative treatment approach based on chemotherapy was taken by the multidisciplinary oncology board.
RESUMO
Disease-specific quality of life (QOL) measures have enhanced the capacity of outcome measures to evaluate subtle changes and differences between groups. As many of the QOL measures have been developed in English, they require translation to ensure their usefulness in a multi-cultural and/or international society. Published guidelines provide formal methods to achieve cross-culturally comparable versions of a QOL tool. The aim of this study was to adapt the head and neck specific module of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-H&N 35 questionnaire) into Moroccan Arabic and to determine its psychometric properties. After translation, back translation and pretesting of the pre-final version, the translated version was submitted to a committee of professionals composed by otolaryngologists and epidemiologists. The psychometric properties were tested in patients with ENT cancer. Internal consistency was tested using Cronbach's alpha and the test-retest reliability using interclass correlation coefficients. Construct validity was assessed by examining item convergent and divergent validity. It was also tested using Spearman's correlation between QLQ-H&N 35 scales and EQ-5D. The study was conducted in 120 patients. The Moroccan version was internally reliable, Cronbach's α ranged from 0.71 for "trouble with social contact" to 0.94 for "senses impairment", indicating good internal consistency. Test-retest reliability was assessed using the intra-class correlation coefficient, which ranged from 0.64 for "speech trouble" to 0.89 for "physical activities". The instrument demonstrated a good construct and concomitant validity. We have developed a semantically equivalent translation with cultural adaptation of EORTC QLQ-H&N 35 questionnaire. The assessment of its measurement properties showed that it is quite reliable and a valid measure of the effect of cancer on the quality of life in Moroccan patients.
Assuntos
Árabes , Neoplasias de Cabeça e Pescoço/etnologia , Neoplasias de Cabeça e Pescoço/psicologia , Qualidade de Vida , Adulto , Idoso , Comparação Transcultural , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Marrocos , Psicometria , Reprodutibilidade dos Testes , Inquéritos e Questionários , TraduçõesRESUMO
The authors comment on the reliability of the scalp flap pedicled on auricular posterior artery, arguing with the conclusions of anatomic studies published in this issue and their little experience in reconstructing scalp defects by local flaps.
Assuntos
Reprodutibilidade dos Testes , Couro Cabeludo/cirurgia , Artérias/cirurgia , Humanos , Procedimentos de Cirurgia Plástica , Retalhos Cirúrgicos/irrigação sanguíneaRESUMO
INTRODUCTION: Trichoblastic carcinoma is a rare malignant adnexal tumor. Its presentation is non-specific and the diagnosis is always histological. CASE REPORT: A 56-year-old patient presented with a trichoblastic carcinoma of the eyelid and eyebrow. It was located on the lower end of the scar, 7 years after the incomplete excision of a tumor. There was a large subcutaneous extension of the tumor, well beyond the visible margins of the skin lesion. The treatment was a broad surgical excision followed by radiotherapy. There was neither local recurrence nor metastasis 20 months later. DISCUSSION: This clinical presentation was atypical and had never been reported. We discuss the therapeutic management of this rare tumor.
Assuntos
Sobrancelhas/patologia , Neoplasias Palpebrais/patologia , Neoplasias de Anexos e de Apêndices Cutâneos/patologia , Neoplasias Cutâneas/patologia , Neoplasias Palpebrais/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias de Anexos e de Apêndices Cutâneos/cirurgia , Neoplasias Cutâneas/cirurgiaAssuntos
Dor Facial/etiologia , Displasia Fibrosa Óssea/diagnóstico , Mucocele/diagnóstico , Crânio , Seio Esfenoidal , Criança , Diagnóstico Diferencial , Dor Facial/cirurgia , Seguimentos , Humanos , Imageamento por Ressonância Magnética , Masculino , Mucocele/cirurgia , Crânio/patologia , Seio Esfenoidal/patologia , Seio Esfenoidal/cirurgia , Tomografia Computadorizada por Raios XRESUMO
Solitary extramedullary plasmacytoma of the thyroid gland is an uncommon condition. Up to date, its clinical pathological features are not fully understood. We present a case of an extramedullary nonmucosal plasmacytoma of the thyroid gland which is the first case with regional metastatic lymph nodes. This condition requires a scrupulous survey to rule out a metastatic multiple myeloma. Although localized forms management is still controversial, authors require combined approach for regional metastatic forms. The prognosis is favorable compared to solitary bone plasmacytomas or multiple myeloma.
Assuntos
Encefalite/microbiologia , Mucormicose/diagnóstico , Sinusite/microbiologia , Adolescente , Anfotericina B/uso terapêutico , Antifúngicos/uso terapêutico , Celulite (Flegmão)/diagnóstico , Celulite (Flegmão)/microbiologia , Doenças dos Nervos Cranianos/etiologia , Diagnóstico Tardio , Complicações do Diabetes/microbiologia , Progressão da Doença , Suscetibilidade a Doenças , Encefalite/complicações , Encefalite/diagnóstico , Encefalite/tratamento farmacológico , Evolução Fatal , Feminino , Fungemia/tratamento farmacológico , Fungemia/etiologia , Fungemia/microbiologia , Humanos , Masculino , Pessoa de Meia-Idade , Mucormicose/complicações , Mucormicose/tratamento farmacológico , Insuficiência de Múltiplos Órgãos/etiologia , Infecções Oportunistas/microbiologia , Sinusite/complicações , Sinusite/diagnóstico , Sinusite/tratamento farmacológico , Transtornos da Visão/etiologiaRESUMO
INTRODUCTION: Mucoepidermoid carcinoma of the parotid gland is a rare malignant tumor mostly affecting adults. It accounts for 1 to 3 % of head and neck malignant tumors. It is very rarely observed in children under 10 years of age. OBSERVATION: A four-and-half-year-old boy was brought to consultation in our department, in June 2006, for a left cervical swelling having progressively increased over the previous two years. Cervical US confirmed the presence of a 2.3cm long tumor of the left parotid area, hyperechogenic and heterogenic, associated to a homolateral lymphadenopathy in the jugular and carotid region (zone II), 2cm in diameter. A total parotidectomy preserving the facial nerve was performed. The biopsy extemporaneous histological examination suggested a low-grade mucoepidermoid carcinoma. Surgery was completed by functional neck dissection. DISCUSSION: Our four-and-half-year-old patient was one of the youngest cases ever reported. Malignant parotid gland tumors are very rarely observed in children: less than 19 cases have been published worldwide. Its occurrence in a young child under ten years of age is very rare. Mucoepidermoid carcinoma accounts for one third of all malignant parotid gland tumors.
Assuntos
Carcinoma Mucoepidermoide/diagnóstico , Neoplasias Parotídeas/diagnóstico , Biópsia , Carcinoma Mucoepidermoide/diagnóstico por imagem , Pré-Escolar , Humanos , Linfonodos/diagnóstico por imagem , Imageamento por Ressonância Magnética , Masculino , Esvaziamento Cervical , Neoplasias Parotídeas/diagnóstico por imagem , UltrassonografiaAssuntos
Carcinossarcoma/diagnóstico , Neoplasias Laríngeas/diagnóstico , Idoso , Biópsia , Carcinossarcoma/etiologia , Carcinossarcoma/terapia , Disfonia/etiologia , Dispneia/etiologia , Humanos , Neoplasias Laríngeas/etiologia , Neoplasias Laríngeas/terapia , Laringectomia , Laringoscopia , Masculino , Pessoa de Meia-Idade , Marrocos , Estadiamento de Neoplasias , Prognóstico , Radioterapia Adjuvante , Fumar/efeitos adversos , Tomografia Computadorizada por Raios XRESUMO
The parotid teratoma is a rare embryonic tumoral malformation containing more or less differentiated derivatives, with malignant potentiality of the three embryonic layers. It poses the problem of the complete excision for the surgeon and the problem of immature elements search for the anatomopathologist. In the light of a new observation and data of the literature, the authors propose to stress the clinical, histological and therapeutic aspects of this affection.
Assuntos
Neoplasias Parotídeas/cirurgia , Teratoma/cirurgia , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias Parotídeas/diagnóstico por imagem , Teratoma/diagnóstico por imagem , Tomografia Computadorizada por Raios XRESUMO
Langerhans histiocytosis is a disease with a very diverse clinical spectrum and a very varied prognosis. The thyroid localization is relatively rare, and raises diagnostic and therapeutic difficulties. Diagnosis often requires recourse to clinical, radiological and pathological confrontation. Combined medical and surgical treatment is indicated and requires close multidisciplinary cooperation. On the basis of a new observation and data in the literature, we present a progress report on the clinical and therapeutic options preferred by various authors.
Assuntos
Histiocitose de Células de Langerhans/diagnóstico , Doenças da Glândula Tireoide/diagnóstico , Diagnóstico Diferencial , Ecocardiografia , Histiocitose de Células de Langerhans/diagnóstico por imagem , Histiocitose de Células de Langerhans/epidemiologia , Humanos , Incidência , Radiografia , Doenças da Glândula Tireoide/diagnóstico por imagemRESUMO
INTRODUCTION: Desmoid tumor is a benign microscopic tumor that belongs to the group of the deep fibromatosis. It usually arises from facial or musculoaponeurotic structures in the abdomen but rarely is located in the head or neck. Locally, it is characterized by a massive invasion with strong potential for recurrence. CASE REPORT: A 37-year-old woman was hospitalized for a swelling of the left parotid gland region which had progressed for eight years. Physical examination revealed a tumor in the parotid gland, which was hard and adherent deeply, measuring 4 cm/3 cm and sensitive to palpation; without satellite nodes nor facial paralysis. The treatment consisted in a superficial parotidectomy. Pathology was in favor of a desmoid tumor. After an 18-month follow-up, the patient is healthy without any sign of recurrence. DISCUSSION: Desmoid tumors are deep fibromatosis characterized by their slow growth and especially by considerable infiltration of the adjacent structures but without potential for metastasis. Although very rare, the cervical localizations are especially aggressive. This clinical case illustrates the clinical features of this rare affection and offers matter for discussion of therapeutic difficulties.
Assuntos
Fibromatose Agressiva/patologia , Neoplasias Parotídeas/patologia , Adulto , Feminino , Fibromatose Agressiva/cirurgia , Humanos , Neoplasias Parotídeas/cirurgiaRESUMO
INTRODUCTION: Neuroendocrine carcinomas are rarely observed in the parotid gland. CASE REPORT: A 65-year-old woman with an uneventful history was hospitalised for a tumor in the left parotid gland which had progressed for 8 months. The clinical manifestations and the radiological findings were in favour of a malignant process involving the parotid gland. Search for local and regional extension was considered to be negative. The surgical procedure was very difficult but enabled conservative resection of the tumor by total parotidectomy. Pathology results were in favour of a neuroendocrine carcinoma of the parotid gland. External radiotherapy was proposed, but interrupted by the patient after having received 40 Gy. After a 13 month follow-up, the patient was in good general condition without any sign of relapse or metastasis. CONCLUSION: Parotid neuroendocrine carcinomas are rare but need to be individualized owing to their poor prognosis with frequent occurrence of hepatic and pulmonary metastasis.
Assuntos
Carcinoma Neuroendócrino/diagnóstico por imagem , Neoplasias Parotídeas/diagnóstico por imagem , Idoso , Carcinoma Neuroendócrino/patologia , Carcinoma Neuroendócrino/radioterapia , Feminino , Seguimentos , Humanos , Neoplasias Parotídeas/patologia , Neoplasias Parotídeas/radioterapia , Dosagem Radioterapêutica , Tomografia Computadorizada por Raios XRESUMO
UNLABELLED: Sub-mandibulary gland tumours are less common than tumours of the parotid and pose many clinical and therapeutic challengers. OBJECTIVE: We report our experience of sub-mandibular tumours and review the literature. PATIENTS AND METHODS: Retrospective studies of sub-mandibular gland tumours presenting to our department between 1986 and 2000. RESULTS: 68 cases were reviewed comprising 37 benign and 31 malignant tumours (15 females and 33 males). Average age of patient was 46 years and all presented with a sub-mandibular swelling. Clinical suspicion of malignancy was associated with symptom of pain, cervical adenopathy, nerve palsy, skin and/or bone invasion. CAT Scans were performedd to assess tumour extent / invasion. Definitive diagnosis was by complete excision and pathological examination. Pleomorphic adenoma (n= 32) were the most frequent benign tumours. For malignant lesions (n= 31) the most frequent were: Adenoid cystic carcinoma (n= 10), epidermoid carcinoma (n= 5), adenocarcinoma (n= 5), mucoepidermoid carcinoma (n= 3), malignant non Hodgkinien lymphoma (n= 5). Treatment was by total surgical excision of the submandibular gland for the begnin tumours. For the malignant lesions it was associated acording to their extension with other anatomical region or in case of adenopathy with neck dissection. Radiotherapy was performed in 24 cases and chemotherapy in 10 cases. CONCLUSION: Malignity in sub-mandibular gland tumours is more frequent than in the parotid gland. Any delay in diagnosis or inappropriate management may result in a poor prognosis for the patient.
Assuntos
Neoplasias da Glândula Submandibular/classificação , Neoplasias da Glândula Submandibular/diagnóstico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Diagnóstico Precoce , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico , Neoplasias da Glândula Submandibular/terapiaRESUMO
INTRODUCTION: Osteoma is the most frequent benign tumor of paranasal sinuses. It is generally asymptomatic and usually discovered by chance during radiological imaging. Three cases with orbital extension are reported and discussed. OBSERVATIONS: 1st observation: Mrs. M.N. is an 18 years-old caucasian female who presented a stony orbital deformity associated with chronical dacryocystitis. Tomography of the orbit revealed a probable ethmoidal osteoma compressing the lacrimal canals. The management consisted in a surgical excision of the whole tumor by external approach, associated with a dacryocystorhinostomy. The patient's follow-up for the last 12 months was normal. 2nd observation: Miss K.A. is a 16 years-old caucasian female who came to consultation for a swelling of the medial angle of the left eye. Computed tomography images showed a fronto-ethmoidal process displaying a bone density consistent with an osteoma. The tumor was removed through an external ethmoidectomy. The patient was free of symptoms at 6 months follow-up. 3rd observation: Mrs. F. Z. is a 45 years-old patient who presented a 5 years history of right painful exophthalmos. The computed tomography was consistent with a fronto-ethmoidal osteoma with intraorbital extension near the optic nerve. The surgical excision was limited to the intraorbital portion. Postoperative complications included ptosis and diplopia. DISCUSSION: Osteomas most commonly affect the fronto-ethmoid sinuses. They rarely show intraorbital extension or cause intracranial complications. They are generally asymptomatic. Symptoms are generally of late onset and are a consequence of tumoral growth and compression of neighbouring organs, as it is the case in our patients. Tumoral exophtalmos is the major ophthalmological sign. The computed tomography is of a great contribution, not only for diagnosis but also for the choice of the surgical approach. The classical surgical technique consists generally in a surgical excision of the osteoma. This surgery may induce ocular or neurochirurgical complications. CONCLUSION: Osteomas of the paranasal sinuses are usually asymptomatic. If they become voluminous, they may cause orbital manifestations and serious complications. The rarity of ethmoidal osteoma with orbital growth made our cases interesting to report.
Assuntos
Neoplasias Orbitárias/diagnóstico , Osteoma/diagnóstico , Adolescente , Adulto , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias Orbitárias/cirurgia , Osteoma/cirurgiaRESUMO
INTRODUCTION: The aim of this study is to emphasize the difficulties of diagnosing parotid gland tuberculosis because of its non specific symptoms and to incite the physician to seek it more frequently. MATERIAL AND METHOD: Six cases of parotid gland tuberculosis were diagnosed within a 4-year period and included in a retrospective study. RESULTS: There were two men and four women, mean age 45 years. Four patients underwent superficial parotidectomy with frozen section analysis which enabled us to rectify the diagnosis. Medical treatment was based on a 6-month course of bactericidal chemotherapy. Outcome was favorable in all the cases with nine months average follow. DISCUSSION: Symptoms of parotid gland are misleading, pathologic findings are of increasing importance for diagnosis, which with the new serology techniques may improve further.
Assuntos
Doenças Parotídeas/diagnóstico , Tuberculose Bucal/diagnóstico , Adulto , Idoso , Antibacterianos/uso terapêutico , Antituberculosos/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Parotídeas/tratamento farmacológico , Doenças Parotídeas/cirurgia , Estudos Retrospectivos , Tuberculose Bucal/tratamento farmacológico , Tuberculose Bucal/cirurgiaRESUMO
INTRODUCTION: Primary hydatid cyst of thyroid gland is an exceptional localization. The thyroid gland is an uncommon site even in Morocco where echinococcal disease is endemic. The aim of this study was to report our experience of this rare disease, and to review diagnosis problems and management. PATIENTS AND METHOD: Retrospective study of six patients with primary hydatid cyst of thyroid gland during a 4-year period. RESULTS: We report six cases of primary hydatid cyst of thyroid gland. Symptoms were isolated thyroid nodules. Diagnosis was based on echography and echinococcal immunologic test. However, hydatic origin was suspected in only 50% of patients preoperatively and immunologic test had 33% false positive rate. Surgical management was a lobo-isthmectomy with a total resection of the cyst in four cases (67%) and a resection of the cyst prominent dome in two cases (33%). Diagnosis was always confirmed by macroscopic aspects and pathology. In all cases, the postoperative course was uneventful and no recurrence occurred with a 19 months follow up. CONCLUSION: Primary hydatid cyst of thyroid gland is a potential but rare situation. Positive diagnosis can be difficult during preoperative period. Cyst size and diagnosis doubt are two crucial criteria to decide the optimal surgical strategy (lobo-isthmectomy with total cyst resection vs resection of the cyst prominent dome).
Assuntos
Equinococose , Doenças da Glândula Tireoide , Adolescente , Adulto , Equinococose/diagnóstico , Equinococose/diagnóstico por imagem , Equinococose/patologia , Equinococose/cirurgia , Feminino , Seguimentos , Humanos , Pessoa de Meia-Idade , Estudos Retrospectivos , Doenças da Glândula Tireoide/diagnóstico , Doenças da Glândula Tireoide/diagnóstico por imagem , Doenças da Glândula Tireoide/patologia , Doenças da Glândula Tireoide/cirurgia , Glândula Tireoide/patologia , Fatores de Tempo , UltrassonografiaRESUMO
OBJECTIVES: The aims of this study were to emphasize the difficulties of diagnosing thyroid tuberculosis because of its non specific symptoms and to encourage physicians to seek it more frequently. MATERIAL AND METHODS: Six cases of thyroid tuberculosis diagnosed within a 3-year period were included in a retrospective study. RESULTS: There were two men and four women, mean age 45 years. Four patients underwent lobo-isthmectomy with frozen section analysis which enabled us to rectify the diagnosis. Medical treatment was based on a 6-month course of bactericidal chemotherapy. Outcome was favorable in all the cases with 17 months average follow up. CONCLUSION: Symptoms of thyroid tuberculosis are misleading, pathologic findings are of increasing importance for diagnosis, which with the new serology techniques may improve further.
Assuntos
Doenças da Glândula Tireoide/diagnóstico , Doenças da Glândula Tireoide/microbiologia , Tuberculose Endócrina/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Antituberculosos/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Doenças da Glândula Tireoide/patologia , Doenças da Glândula Tireoide/terapia , Tireoidectomia/métodos , Resultado do Tratamento , Tuberculose Endócrina/patologia , Tuberculose Endócrina/terapiaRESUMO
INTRODUCTION: Actinomycosis of the middle ear are rare and often atypical and remain ignored for a long time. This delayed the diagnosis and obscured the forecast of the disease. AIM OF STUDY: Our objective is to give a progress report on this affection in the light of a new observation and data of the literature. CLINICAL CASE: 58 year old patient who consults of a left chronic otitis media with a posterior perforation. A CT scan had shown a filling of the middle ear in favour of a cholesteatoma. A tympano-mastoidectomy was realized and the histological examination of the product of excision had sowed that it acts of an actinomycosis of the middle ear. The treatment consisted of penicillin for 5 months. The continuations are good after 14 months of follow-up. CONCLUSION: The actinomycosis of the middle ear must be known to evoke the diagnosis in various clinical circumstances. Its diagnosis makes it possible to adopt an adapted and non aggressive therapeutic attitude, avoiding heavy surgical gestures, sources of complications or after-effects. The antibiotherapy containing penicillin is the essential element, either separately, or in complement of gestures of surgical drainage.