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1.
Bone Joint J ; 99-B(7): 958-963, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28663404

RESUMO

AIMS: Hip hemiarthroplasty is a standard treatment for intracapsular proximal femoral fractures in the frail elderly. In this study we have explored the implications of early return to theatre, within 30 days, on patient outcome following hip hemiarthroplasty. PATIENTS AND METHODS: We retrospectively reviewed the hospital records of all hip hemiarthroplasties performed in our unit between January 2010 and January 2015. Demographic details, medical backround, details of the primary procedure, complications, subsequent procedures requiring return to theatre, re-admissions, discharge destination and death were collected. RESULTS: A total of 705 procedures were included; 428 Austin Moore and 277 Exeter Trauma Stems were used. A total of 34 fractures (in 33 patients) required early return to theatre within 30 days. Age, gender, laterality, time from admission to primary procedure, American Society of Anesthesiologists grade, and implant type were similar for those requiring early return to theatre and those who did not. Early return to theatre was associated with a significantly higher length of stay (mean 33.6 days (7 to 107) versus 18.6 days (0 to 152), p < 0.001), re-admission rate (38.2% versus 8.6%, p < 0.001), and subsequent revision rate (17.6% versus 1.3%, p < 0.001). We found no difference in level of care required on discharge or mortality. CONCLUSION: Proximal femoral fractures are common in the elderly population, with far-reaching medical and economic implications. Factors such as infection or dislocation may require early return to theatre, and this is associated with outcomes which may be both medically and economically detrimental. This illustrates the importance of avoiding early complications to improve longer term outcome. Return to theatre within 30 days is associated with longer length of stay, higher re-admission rate, and higher subsequent revision rate. It may be a useful short-term quality indicator for longer term outcome measures following hip hemiarthroplasty for intracapsular fractures of the proximal femur. Cite this article: Bone Joint J 2017;99-B:958-63.


Assuntos
Fraturas do Colo Femoral/cirurgia , Hemiartroplastia , Reoperação/estatística & dados numéricos , Idoso de 80 Anos ou mais , Feminino , Fraturas do Colo Femoral/epidemiologia , Humanos , Tempo de Internação/estatística & dados numéricos , Masculino , Readmissão do Paciente/estatística & dados numéricos , Complicações Pós-Operatórias , Estudos Retrospectivos , Resultado do Tratamento
3.
J Bone Joint Surg Br ; 91(6): 835-42, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19483243

RESUMO

We carried out a cross-sectional study with analysis of the demographic, clinical and laboratory characteristics of patients with metal-on-metal hip resurfacing, ceramic-on-ceramic and metal-on-polyethylene hip replacements. Our aim was to evaluate the relationship between metal-on-metal replacements, the levels of cobalt and chromium ions in whole blood and the absolute numbers of circulating lymphocytes. We recruited 164 patients (101 men and 63 women) with hip replacements, 106 with metal-on-metal hips and 58 with non-metal-on-metal hips, aged < 65 years, with a pre-operative diagnosis of osteoarthritis and no pre-existing immunological disorders. Laboratory-defined T-cell lymphopenia was present in 13 patients (15%) (CD8(+) lymphopenia) and 11 patients (13%) (CD3(+) lymphopenia) with unilateral metal-on-metal hips. There were significant differences in the absolute CD8(+) lymphocyte subset counts for the metal-on-metal groups compared with each control group (p-values ranging between 0.024 and 0.046). Statistical modelling with analysis of covariance using age, gender, type of hip replacement, smoking and circulating metal ion levels, showed that circulating levels of metal ions, especially cobalt, explained the variation in absolute lymphocyte counts for almost all lymphocyte subsets.


Assuntos
Artroplastia de Quadril/efeitos adversos , Cromo/sangue , Cobalto/sangue , Linfopenia/sangue , Estudos Transversais , Feminino , Prótese de Quadril , Humanos , Linfopenia/complicações , Masculino , Pessoa de Meia-Idade , Desenho de Prótese
4.
J Bone Joint Surg Br ; 89(12): 1655-9, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18057369

RESUMO

The biological significance of cobalt-chromium wear particles from metal-on-metal hip replacements may be different to the effects of the constituent metal ions in solution. Bacteria may be able to discriminate between particulate and ionic forms of these metals because of a transmembrane nickel/cobalt-permease. It is not known whether wear particles are bacteriocidal. We compared the doubling time of coagulase negative staphylococcus, Staphylococcus aureus and methicillin resistant S. aureus when cultured in either wear particles from a metal-on-metal hip simulator, wear particles from a metal-on-polyethylene hip simulator, metal ions in solution or a control. Doubling time halved in metal-on-metal (p = 0.003) and metal-on-polyethylene (p = 0.131) particulate debris compared with the control. Bacterial nickel/cobalt-transporters allow metal ions but not wear particles to cross bacterial membranes. This may be useful for testing the biological characteristics of different wear debris. This experiment also shows that metal-on-metal hip wear debris is not bacteriocidal.


Assuntos
Cobalto/farmacologia , Prótese de Quadril , Níquel/farmacologia , Staphylococcus/efeitos dos fármacos , Artroplastia de Quadril , Meios de Cultura , Humanos , Teste de Materiais/métodos , Resistência a Meticilina , Polietileno , Desenho de Prótese , Falha de Prótese , Soluções , Staphylococcus/crescimento & desenvolvimento , Staphylococcus aureus/classificação , Staphylococcus aureus/efeitos dos fármacos
5.
Ann R Coll Surg Engl ; 88(3): 297-301, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16720002

RESUMO

INTRODUCTION: We monitored image intensifier use by orthopaedic trainees to assess their exposure to ionising radiation and to investigate the influence of sub-specialty training. MATERIALS AND METHODS: Five different orthopaedic registrars recorded their monthly image intensifier screening times and exposure doses for all cases (trauma and elective), for a combined total of 12 non-consecutive months. Radiation exposure was monitored using shoulder and waist film badges worn both by surgeons and radiographers screening their cases. RESULTS: Registrars in spinal sub-specialties were exposed to significantly higher doses per case and cumulative doses per month than non-spinal trainees (P < 0.05), but significantly lower screening times per case (P < 0.05). There were no significant differences in cumulative screening times per month (P > 0.05). Regression analysis for all surgeons showed a significant relationship between shoulder film badge reading and cumulative dose exposed per month (P < 0.05), but not for cumulative screening time. Shoulder film badge recordings were significantly higher for spinal compared with non-spinal registrars (P < 0.05), although all badges were below the level for radiation reporting. Only one radiographer badge recorded a dose above threshold. CONCLUSIONS: Whilst the long-term effects of sub-reporting doses of radiation are not fully understood, we consider that this study demonstrates that trainees should not be complacent in accepting inadequate radiation protection. The higher doses encountered with spinal imaging means that sub-specialty trainees should be alerted to the risk of their increased exposure. The principle of minimising radiation exposure must be maintained by all trainees at all times.


Assuntos
Exposição Ocupacional/prevenção & controle , Ortopedia , Doses de Radiação , Radiação Ionizante , Dosimetria Fotográfica/métodos , Humanos , Corpo Clínico Hospitalar/educação , Exposição Ocupacional/efeitos adversos , Proteção Radiológica/métodos , Estudantes de Medicina
7.
Theor Appl Genet ; 105(6-7): 1087-1096, 2002 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-12582937

RESUMO

The genus Salix (willow) contains a number of species of great value as biomass crops. Efforts to breed varieties with improved biomass yields and resistances to pests and diseases are limited by the lack of knowledge on the genetic basis of the traits. We have used AFLP and microsatellite markers to construct a genetic map of willow from a full-sib cross of the diploid species Salix viminalis (2n = 38). In accordance with a double pseudo-testcross approach, separate parental maps were constructed and merged to produce a consensus map comprising 291 AFLP and 39 willow microsatellite markers. Nineteen poplar microsatellites were also tested in willow. Five of these amplified loci, of which two were mapped. Linkage groups of the consensus map that could be identified in the parental maps are presented here and spanned 1,256.5 cM with an average interval between markers of 4.4 cM.

8.
J Arthroplasty ; 16(5): 635-40, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11503124

RESUMO

Component angles of 673 Press Fit Condylar (PFC) total knee arthroplasties were measured from standard short-leg radiographs. The femoral and tibial resections were performed with intramedullary and extramedullary instrumentation. The mean coronal tibial component angle was 88.59 degrees (SD, 2.28 degrees; range, 78-98 degrees ), with 17.1% having values <87 degrees and 1.9% having values >93 degrees. The mean coronal femoral component angle was 97.43 degrees (SD, 3.44 degrees; range, 84-115 degrees ), with 9.1% having values <94 degrees and 13.1% having values >100 degrees. An ideal tibiofemoral angle of 4 degrees to 10 degrees of valgus was achieved in 75.3% of patients, being <4 degrees in 18.6% and >10 degrees in 6.1%. Alignment was not significantly different between consultant and trainee surgeons. Although varus positioning of the tibial component was the commonest error, the wide range of femoral component angles signifies problems with standard intramedullary femoral guides.


Assuntos
Artroplastia do Joelho , Competência Clínica , Articulação do Joelho/diagnóstico por imagem , Prótese do Joelho , Mau Alinhamento Ósseo/diagnóstico por imagem , Fêmur/diagnóstico por imagem , Humanos , Articulação do Joelho/cirurgia , Radiografia , Tíbia/diagnóstico por imagem , Resultado do Tratamento
9.
Genome ; 44(6): 962-70, 2001 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-11768223

RESUMO

AFLP and SSR DNA markers were used to construct a linkage map in the coconut (Cocos nucifera L.; 2n = 32) type Rennell Island Tall (RIT). A total of 227 markers were arranged into 16 linkage groups. The total genome length corresponded to 1971 cM for the RIT map, with 5-23 markers per linkage group. QTL analysis for yield characters in two consecutive sampling periods identified nine loci. Three and two QTLs were detected for number of bunches and one and three QTLs for number of nuts. The correlation of trait values between characters and evaluation periods is partially reflected in identical QTLs. The QTLs represent characters that are important in coconut breeding. The cosegregation of markers with these QTLs provides an opportunity for marker-assisted selection in coconut breeding programmes.


Assuntos
Mapeamento Cromossômico , Cocos/genética , Característica Quantitativa Herdável , Marcadores Genéticos , Genoma de Planta , Escore Lod , Polimorfismo Genético
10.
Injury ; 31(9): 729-36, 2000 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11084162

RESUMO

A prospective study of 21 triplane fractures of the distal tibia is presented. Nineteen cases (90.5%) had lateral triplane fractures, while the other two (9.5%) had medial triplane fractures. Two fragment fractures were encountered in 12 cases (57%); three fragment fractures in six cases (29%), and four fragment fractures in the remaining three cases (14%). Fourteen cases (67%) were managed non-operatively, while in seven cases (33%), open reduction and internal fixation was performed. Twenty patients (95%) were pleased with the final outcome. Objectively, 14 cases (67%) achieved excellent results.


Assuntos
Fraturas da Tíbia/diagnóstico por imagem , Adolescente , Parafusos Ósseos , Fios Ortopédicos , Moldes Cirúrgicos , Criança , Epífises/diagnóstico por imagem , Epífises/lesões , Feminino , Fixação de Fratura/métodos , Humanos , Masculino , Prognóstico , Estudos Prospectivos , Fraturas da Tíbia/classificação , Fraturas da Tíbia/terapia , Tomografia Computadorizada por Raios X , Resultado do Tratamento
11.
J Arthroplasty ; 15(2): 238-40, 2000 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-10708094

RESUMO

Necrotizing fasciitis is a rare, but life-threatening emergency. We report a case history of necrotizing fasciitis in a previously healthy woman. A review of the literature suggests that this is the first report of necrotizing fasciitis complicating total hip replacement surgery.


Assuntos
Artroplastia de Quadril/efeitos adversos , Fasciite Necrosante/epidemiologia , Idoso , Feminino , Humanos , Complicações Pós-Operatórias/epidemiologia
13.
J Bone Joint Surg Br ; 79(3): 371-3, 1997 May.
Artigo em Inglês | MEDLINE | ID: mdl-9180311

RESUMO

An intact barrier between the hands of the surgeon and the patient remains the single most important factor in protection against infection for both. Increasing the awareness of possible glove perforation without skin penetration will decrease the risk of contamination. We performed a prospective, randomised trial comparing the incidence of glove perforation using a new type of glove (Regent Biogel Reveal) and standard double-gloves in total hip and knee replacement. One or more perforations was detected in 14.6% of all gloves. The new gloves increased significantly the awareness of perforation. Multiple perforations at the base of the ring finger were found in surgeons who wore wedding rings during the operation and we recommend that rings be removed before undertaking surgery.


Assuntos
Luvas Cirúrgicas , Prótese de Quadril/instrumentação , Prótese do Joelho/instrumentação , Distribuição de Qui-Quadrado , Falha de Equipamento/estatística & dados numéricos , Luvas Cirúrgicas/estatística & dados numéricos , Humanos , Estudos Prospectivos
14.
Spine (Phila Pa 1976) ; 15(6): 495-9, 1990 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-2144913

RESUMO

Two separate samples of 50 workers' compensation patients were assessed within 3 to 6 months of their first back injury and were reassessed at a mean of 13.7 months postinjury, at which time work status was also determined. A number of predictors on the first assessment then were correlated with return to work. These predictors included orthopaedic evaluations of severity and prognosis, the number of nonorganic physical signs, Minnesota Multiphasic Personality Inventory (MMPI) scales 1 and 3, age, education, proficiency in English, and the accuracy of patients' understanding of the bases for their medical condition as determined by the Schema Assessment Instrument (SAI). The SAI was the only variable to predict return to work significantly in both samples. These data point to the importance of patients' understanding of their medical condition for their prognosis.


Assuntos
Dor nas Costas/diagnóstico , Avaliação da Deficiência , Doenças Profissionais/diagnóstico , Adulto , Atitude Frente a Saúde , Feminino , Humanos , MMPI , Masculino , Ontário , Prognóstico , Tolerância ao Trabalho Programado , Indenização aos Trabalhadores
15.
J Bone Joint Surg Br ; 71(3): 486-8, 1989 May.
Artigo em Inglês | MEDLINE | ID: mdl-2722945

RESUMO

A new method of repair of the calcaneal tendon, which uses a small transverse skin incision, is described. In 41 patients, there was only one minor wound problem and the clinical results were satisfactory.


Assuntos
Tendão do Calcâneo/cirurgia , Tendão do Calcâneo/lesões , Humanos , Métodos , Ruptura
16.
Spine (Phila Pa 1976) ; 13(5): 557-60, 1988 May.
Artigo em Inglês | MEDLINE | ID: mdl-2973133

RESUMO

The value of the nonorganic signs in predicting return to activity following an initial episode of low-back pain was determined. One hundred and twenty patients were assessed within 6 months of the onset of their first episode of disabling low-back pain and again at a mean of 15.3 months following injury. No correlation was found between the presence of nonorganic signs at initial assessment and either return to activity or resolution of the patient's symptoms.


Assuntos
Dor nas Costas/fisiopatologia , Trabalho , Adolescente , Adulto , Idoso , Previsões , Humanos , Pessoa de Meia-Idade , Estudos Prospectivos , Fatores de Tempo
17.
J Bone Joint Surg Br ; 68(4): 520-7, 1986 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-3733823

RESUMO

Between 1965 and 1973 a total of 808 McKee-Farrar metal-on-metal cemented total hip arthroplasties were performed in the Norfolk and Norwich Hospital. Of these, 230 surviving arthroplasties have been reviewed at average follow-up of 13.9 years. There were good or excellent results in 49% of the arthroplasties as judged by the Harris hip score with 78% of these having little or no pain. A comprehensive radiographic analysis was undertaken and a survivorship study of 81% of the total number of prostheses is presented.


Assuntos
Prótese de Quadril , Adulto , Idoso , Comportamento do Consumidor , Feminino , Seguimentos , Articulação do Quadril/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia
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