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2.
Curr Heart Fail Rep ; 15(4): 280, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29744760

RESUMO

The original version of this article, published in Current Heart Failure Reports, Volume 14, Issue 5, October 2017, erroneously cited an author's name as Marshall Brinkley, D" when it should be "Brinkley, DM."

3.
Curr Heart Fail Rep ; 14(5): 410-420, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28808858

RESUMO

PURPOSE: Vitamin D is principally known for its role in calcium homeostasis, but preclinical studies implicate multiple pathways through which vitamin D may affect cardiovascular function and influence risk for heart failure. Many adults with cardiovascular disease have low vitamin D status, making it a potential therapeutic target. We review the rationale and potential role of vitamin D supplementation in the prevention and treatment of chronic heart failure. RECENT FINDINGS: Substantial observational evidence has associated low vitamin D status with the risk of heart failure, ventricular remodeling, and clinical outcomes in heart failure, including mortality. However, trials assessing the influence of vitamin D supplementation on surrogate markers and clinical outcomes in heart failure have generally been small and inconclusive. There are insufficient data to recommend routine assessment or supplementation of vitamin D for the prevention or treatment of chronic heart failure. Prospective trials powered for clinical outcomes are warranted.


Assuntos
Suplementos Nutricionais , Insuficiência Cardíaca , Remodelação Ventricular/efeitos dos fármacos , Vitamina D/uso terapêutico , Insuficiência Cardíaca/sangue , Insuficiência Cardíaca/tratamento farmacológico , Insuficiência Cardíaca/fisiopatologia , Humanos , Fatores de Risco , Vitamina D/farmacocinética , Vitaminas/farmacocinética , Vitaminas/uso terapêutico
5.
BMJ Case Rep ; 20132013 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-23608846

RESUMO

A pericardial cyst is a rare and benign congenital malformation, usually discovered in the third or fourth decade of life. Its clinical presentation is variable, as it may be asymptomatic or present with chest pain, shortness of breath, or rarely with cardiac tamponade and arrhythmias. We present an interesting case of a woman presenting with chest pain who was found to have a pericardial cyst.


Assuntos
Cisto Mediastínico/diagnóstico por imagem , Dor no Peito/etiologia , Diagnóstico Diferencial , Feminino , Humanos , Cisto Mediastínico/complicações , Cisto Mediastínico/cirurgia , Tomografia Computadorizada por Raios X
6.
BMJ Case Rep ; 20132013 Jan 28.
Artigo em Inglês | MEDLINE | ID: mdl-23362060

RESUMO

A man with end-stage liver disease who presented with shortness of breath. He exhibited clinical platypnea (worsening shortness of breath on sitting up) and orthodeoxia (oxygen desaturation on sitting up). Follow-up investigations led to the diagnosis of hepatopulmonary syndrome.


Assuntos
Dispneia/etiologia , Síndrome Hepatopulmonar/diagnóstico , Postura , Diagnóstico Diferencial , Ecocardiografia , Doença Hepática Terminal/complicações , Coração/fisiopatologia , Síndrome Hepatopulmonar/complicações , Humanos , Masculino , Oxigênio/sangue , Postura/fisiologia
7.
BMJ Case Rep ; 20122012 Sep 24.
Artigo em Inglês | MEDLINE | ID: mdl-23008379

RESUMO

We present an interesting case of an elderly man with acute myocardial infarction due to retrograde dissection of the aortic root occluding the coronary ostia.


Assuntos
Aorta/patologia , Aneurisma Aórtico/complicações , Dissecção Aórtica/complicações , Oclusão Coronária/complicações , Vasos Coronários/patologia , Infarto do Miocárdio/etiologia , Idoso , Humanos , Masculino
8.
Clin Kidney J ; 5(4): 356-8, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25874098

RESUMO

A 58-year old male with a history of small bowel resection and ileostomy presented with severe dehydration and high ostomy output. Laboratory investigation indicated hypochloremia, hypokalemia, hyponatremia, metabolic alkalosis, chloride-rich diarrhea, acute renal failure, and low urinary chloride excretion. Due to striking similarities to congenital chloridorrhea (CCD) reported in neonates, we empirically diagnosed acquired chloridorrhea (ACD, chloride diarrhea). This is a rare disorder resulting in profuse chloride-rich diarrhea and classic metabolic derangements affecting adults with chronic intestinal inflammation, often in association with bowel surgery. In this report, we review the relevant literature and discuss the genetic defects likely contributing to both the congenital and acquired forms of chloridorrhea.

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