1.
Chem Commun (Camb)
; 59(51): 7971-7973, 2023 Jun 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37282981
RESUMO
A robust multigram-scale synthesis of 1,3-disubstituted cubanes (previously only available on milligram-scale) is reported. The approach exploits a readily available enone intermediate previously used for the synthesis of 1,4-disubstituted cubanes, by introducing a novel Wharton transposition to access useful quantities of 1,3-disubstituted cubanes for diverse applications.