Tumor neuroendocrino bien diferenciado ileal y adenocarcinoma de colon sincrónicos: a propósito de un caso y revisión de la literatura / Synchronous well differentiated ileal neuroendocrine tumour and colonic adenocarcinoma. A case report and a review of the literatura

El adenocarcinoma de colon primario sincrónico con un tumor neuroendocrino bien diferenciado ileal es raro y se detecta accidentalmente en autopsias o en el estudio anatomopatológico de piezas resecadas, solo ocasionalmente en la colonoscopia y excepcionalmente en el acto quirúrgico. En este artículo describimos un adenocarcinoma de ciego asociado a un tumor neuroendocrino bien diferenciado de íleon, no detectado en la colonoscopia, con metástasis ganglionares no asociadas a metástasis del adenocarcinoma. En la revisión de la literatura, la asociación de tumores primarios no carcinoides con carcinoides del tracto gastrointestinal puede representar hasta más de un 50% de forma no sincrónica, siendo la incidencia muy rara, entre 1 y 8%, en tumores sincrónicos. Parece claro que el tumor neuroendocrino bien diferenciado es un factor predisponente para desarrollar un segundo tumor primario (AU)

Synchronous colonic adenocarcinoma and well-differentiated ileal neuroendocrine tumour are infrequent and are usually incidental findings on autopsies or resected surgical specimens. Only rarely are they detected on colonoscopies or during surgery. We present a case of a synchronous caecal adenocarcinoma and well-differentiated ileal neuroendocrine tumour, undetected during colonoscopy, with carcinoid metastasis in one regional lymph node not associated with adenocarcinoma metastasis. A review of the literature shows that the association of non-synchronous second primary malignancies in patients with gastrointestinal carcinoid tumours is reported in more than 50% of cases; however, synchronous tumours are found in only 1-8%. It would appear that well-differentiated ileal neuroendocrine tumour could be a predisposing factor for the development of a second malignancy (AU)

[Synchronous well differentiated ileal neuroendocrine tumour and colonic adenocarcinoma. A case report and a review of the literature]. / Tumor neuroendocrino bien diferenciado ileal y adenocarcinoma de colon sincrónicos: a propósito de un caso y revisión de la literatura.

Synchronous colonic adenocarcinoma and well-differentiated ileal neuroendocrine tumour are infrequent and are usually incidental findings on autopsies or resected surgical specimens. Only rarely are they detected on colonoscopies or during surgery. We present a case of a synchronous caecal adenocarcinoma and well-differentiated ileal neuroendocrine tumour, undetected during colonoscopy, with carcinoid metastasis in one regional lymph node not associated with adenocarcinoma metastasis. A review of the literature shows that the association of non-synchronous second primary malignancies in patients with gastrointestinal carcinoid tumours is reported in more than 50% of cases; however, synchronous tumours are found in only 1-8%. It would appear that well-differentiated ileal neuroendocrine tumour could be a predisposing factor for the development of a second malignancy.

Schwannoma benigno retroperitoneal gigante: diagnóstico incidental en paciente con masa pélvica sospechosa de cáncer de ovario / Benign giant retroperitoneal schwannoma: incidental diagnosis in a patient with pelvic mass mimicking ovarian cancer

Las tumoraciones del compartimento sacro son poco frecuentes (1:40.000 ingresos hospitalarios), siendo los tumores benignos más infrecuentes. Los schwannomas son tumores benignos compuestos por células de Schwann con crecimiento lento, permaneciendo las pacientes asintomáticas durante gran parte de su historia natural. Se expone el caso de una paciente de 82 años, sin antecedentes de interés, que presenta masa pélvica y marcadores tumorales negativos, con diagnóstico de sospecha radiológico de cáncer de ovario, filiada como schwannoma benigno retroperitoneal gigante tras estudio anatomopatológico definitivo. Tras tratamiento quirúrgico óptimo, la paciente se encuentra libre de enfermedad tras 5 años de seguimiento (AU)

Sacral tumors are rare (1:40,000 hospital admissions) and benign sacral tumors are even more uncommon. Schwannomas are slow-growing benign tumors composed of Schwann cells and remain asymptomatic for much of their natural history. We report the case of an 82-year-old woman with no relevant medical history and a pelvic mass and negative tumor markers. The presumptive radiological diagnosis was ovarian cancer but the definitive pathological diagnosis was benign giant retroperitoneal schwannoma. After successful surgical treatment, the patient is disease-free after 5 years of follow-up (AU)