Success Rate of Stainless-steel Crowns Placed on Permanent Molars among Adolescents.

AIM AND OBJECTIVE: To evaluate the success rate of stainless-steel crowns (SSCs) placed on permanent molars among adolescents in King Abdulaziz University Dental Hospital (KAUDH). MATERIALS AND METHODS: Electronic records of KAUDH patients aged 10 to 15 years who had an SSC placed on a permanent molar from 2013 to 2018 were reviewed. The patients were contacted by telephone and were invited to participate in the study. The patients were examined clinically and radiographically. RESULTS: The response rate was 42.6%. The total number of SSCs included in the study was 36 crowns. The mean age was 11.75 ± 1.95. Males represented 75.76% of the subjects. The success rate of SSCs placed on permanent molars was 86.10%. CONCLUSION: Placement of SSCs on permanent molars is a highly successful long-term temporary restoration that preserves badly destructed molars in adolescents until definitive prosthetic treatment can be done. CLINICAL SIGNIFICANCE: To provide updated knowledge to healthcare providers and researchers about the success rate of SSCs when placed on permanent molars. HOW TO CITE THIS ARTICLE: Felemban O, Alagl H, Aloufi W, et al. Success Rate of Stainless-steel Crowns Placed on Permanent Molars among Adolescents. Int J Clin Pediatr Dent 2021;14(4):488-491.

Stability issues and approaches to stabilised nanoparticles based drug delivery system.

Nanoparticles form the fundamental building blocks for many exciting applications in various scientific disciplines due to its unique features such as large surface to mass ratio, targeting potential, ability to adsorbed and carry other compound which makes them suitable for biomedical applications. However, the problem of the large-scale synthesis of nanoparticles remains challenging due to physical instability associated with nanoparticles which lead to generation of aggregates particles with high polydispersity index (PDI) indicating low particle homogeneity and eventually loss of their special nanoscale properties. The stabilisation concept can be generated by repulsive electrostatic force, which nanoparticles experience, when they are surrounded by a double layer of electric charges. Selection of proper stabiliser will govern the stability of NPs and ultimately development of optimised drug delivery system. This review summarises mechanism of physical instability issues likely to be encountered during the development of nanoformulations. It also discusses potential stabilising agents used so far and their mechanism in achieving stable nanosystems.