Prognostic and developmental factors in patients receiving liver transplant due to hepatocellular carcinoma: one center's experience in the north of Spain.

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most frequent types of tumor. The aim of this study was to determine the survival of patients who had received liver transplants as a result of the disease. METHODS: This observational follow-up study included 150 patients who received liver transplantations from June 1994 to December 2007. The study considered epidemiological and staging variables, tumor descriptions, and follow-up variables. We employed Kaplan-Meier methodology together with a Cox multivariate regression analysis. RESULTS: The incidence of tumor relapse was 13.3%, with survival rates at 1, 3, and 5 years of 89.3%, 73.1%, and 61.4%, respectively. Variables that showed an independent effect to predict mortality were the degree of histological differentiation and of macrovascular invasion. Patients with poorly differentiated HCC had a 4.03 fold (95% confidence interval [CI]: 1.61-10.06) greater possibility of dying. Macrovascular involvement increased the risk of death (relative risk = 2.23), an effect that was at the limit of significance (95% CI 0.99-5.04). CONCLUSIONS: The survival rate was consistent with the literature. Poor tumor differentiation and macrovascular involvement were independent predictors of mortality.

Sorprendente migración torácica de un proyectil abdominal de arma de aire comprimido / Surprising thoracic migration of an abdominal projectile of a compressed air weapon

No disponible

Perforación de aurícula derecha secundaria a radionecrosis post-mastectomía / No disponible

El empleo de grandes radiaciones ionizantes en el tratamiento del cáncer de mama después de una mastectomía radical ha sufrido un descenso significativo en los últimos años, debido a la introducción de la quimioterapia adyuvante, al auge del tratamiento conservador y a los sustanciales cambios en las técnicas radioterapéuticas, lo que justifica un descenso importante de la toxicidad cardiovascular, secundaria a la radioterapia. Presentamos, un caso excepcionalmente raro, de una mujer anciana que presentó una lesión sangrante paraesternal izquierda crónica con aumento del débito en la última semana, compatible con perforación de la aurícula derecha secundaria a radionecrosis, inducida por el tratamiento que recibió con radioterapia post-mastectomía radical izquierda por un cáncer de mama hace 30 años, en un hospital de otra Comunidad Autónoma(AU)

The use of large ionizing radiations in the treatment of breast cancer after a radical mastectomy has significantly declined in the last years due to the introduction of adjuvant chemotherapy, the increase of the conservative treatment and the substantial changes in radiotherapeutic techniques, which justify a steady decline in the cardiovascular toxicity as a complication of radiotherapy. We present an exceptionally rare case of an elderly woman who presents a chronic left parasternal bleeding injury with increase of the flow during the last week, consistent with perforation of the right auricle as a result of radionecrosis, caused by the treatment with radical left post-mastectomy radiotherapy for breast cancer, received 30 years ago at a hospital of another Autonomous Community in Spain(AU)

Linfangioma quístico abdominal en una adolescente / No disponible

No disponible

Hernia de Morgagni incarcerada en un adulto / No disponible

No disponible

Angiosarcoma primario de bazo / No disponible

No disponible