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1.
Am Surg ; : 31348221148363, 2022 Dec 26.
Artigo em Inglês | MEDLINE | ID: mdl-36571264

RESUMO

BACKGROUND: New York City (NYC) became the epicenter of the COVID-19 pandemic in 2020. The Bronx, with the highest rates of poverty and violent crime of all NYC boroughs and a large Black and Hispanic population, was at increased risk of COVID-19 and its sequelae. We aimed to identify temporal associations among COVID-19 and trauma admission volume, demographics, and mechanism of injury (MOI). METHODS: A retrospective review of prospectively collected data was conducted from a Level II trauma center in the Bronx. January 1st-September 30th for both 2019 (Pre-COVID) and 2020 (COVID) were compared. Pre-COVID and COVID cohorts were subdivided into EARLY (March-May) and LATE (June-September) subgroups. Demographics and trauma outcomes were compared. RESULTS: Trauma admissions were similar between Pre-COVID and COVID. During COVID, there was an increased percentage of Black patients (Black Hispanic 20.1% vs 15.2% and Black Non-Hispanic 39.4% vs 34.1%, P < .05), younger patients (26-35 years old: 22.6% vs 17.6%, P < .05), and out-of-pocket payors (6.0% vs 1.6%, P < .05). Trauma severity outcomes were mixed-some measures supported increased severity; others showed no difference or decreased severity. During COVID, there was a rise in total penetrating injuries (27.4% vs 20.8%, P < .05), MVC (13.2% vs 7.1, P < .05), and firearm injuries (11.6% vs 6.0%, P < .05). Additionally, during LATE COVID, there was a resurgence of total penetrating, total blunt, MVC, falls, cyclists/pedestrians struck, and firearm injuries. DISCUSSION: Our results emphasize MOI variations and racial differences of trauma admissions to a Level II trauma center in the Bronx during COVID-19. These findings may help trauma centers plan during pandemics and encourage outreach between trauma centers and community level organizations following future healthcare disasters.

2.
J Exp Zool A Ecol Integr Physiol ; 335(4): 436-453, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33830677

RESUMO

Arboreal mammals have evolved a range of biomechanical adaptations that allow them to navigate trees effectively. One such feature that has received considerable attention is the importance of vision that helps arboreal animals assess gap distances, assure proper foot placement, and inspect potential risks. While there is considerable debate about the relative importance of the visual system specifics, there is little doubt that the ability to at least see the environment must confer some level of safety when navigating arboreal substrates. In this study, we explore spatiotemporal and kinematic patterns of arboreal locomotion in the Vietnamese pygmy dormouse (Typhlomys chapensis), a blind rodent that uses ultrasonic echolocation to navigate in tree canopies. We compare these data with five other species of arboreal rodents and primates. Spatiotemporal gait characteristics are largely similar between the Vietnamese pygmy dormouse and other small-bodied arboreal species analyzed. Most notable is the tendency for relatively high-speed asymmetrical gaits on large-diameter substrates and slower symmetrical lateral-sequence gaits on small-diameter substrates. Furthermore, for all species speed is primarily regulated by increasing stride frequency rather than length. Kinematics of the Vietnamese pygmy dormouse changed little in response substrate size and were primarily driven by speed. These findings suggest that the information gathered during ultrasonic scanning is sufficient to allow effective quadrupedal locomotion while moving on arboreal supports. The Vietnamese pygmy dormouse may serve as a model for the quadrupedal nocturnal ancestor of bats, which had started developing ultrasonic echolocation and reducing vision while likely occupying an arboreal niche.


Assuntos
Ecolocação/fisiologia , Marcha/fisiologia , Myoxidae/fisiologia , Primatas/fisiologia , Animais , Membro Anterior/fisiologia , Membro Posterior/fisiologia , Masculino , Análise Espaço-Temporal , Especificidade da Espécie , Árvores
3.
Surgery ; 165(1): 37-43, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30274732

RESUMO

OBJECTIVES: We aimed to determine the effect of adjuvant radioactive iodine dose on recurrence rate in high-risk papillary thyroid cancer. METHODS: More than 1,500 patients treated for papillary thyroid cancer at high-volume centers in France and the United States from 2004-2014 were reviewed. Patients considered at high risk for recurrence per the 2015 American Thyroid Association guidelines were analyzed and grouped by initial radioactive iodine dose: intermediate (median 100 mCi) or high dose (median 150 mCi). Propensity score matching was performed to control for baseline characteristics. RESULTS: In a propensity-matched cohort of 66 patient pairs, there were equivalent rates of gross extrathyroidal extension (71% vs 71%, P = 1.00), positive margins (55% vs 55%, P = 1.00), lymph node metastases ≥ 3 cm (9% vs 9%, P = 1.00), extranodal extension (32% vs 33%, P = .85), and distant metastases (2% vs 5%, P = .31). Over a median follow-up of 4.5 years (interquartile ratio 2.0-7.5 years), the intermediate-dose radioactive iodine group had a significantly higher rate of recurrence than patients in the high-dose radioactive iodine group: 24 out of 66 (36%) vs 13 out of 66 (20%), P = .03. CONCLUSION: High-dose radioactive iodine is associated with lower recurrence rate compared with intermediate-dose radioactive iodine for patients with American Thyroid Association high-risk papillary thyroid cancer.


Assuntos
Radioisótopos do Iodo/administração & dosagem , Recidiva Local de Neoplasia/epidemiologia , Câncer Papilífero da Tireoide/terapia , Neoplasias da Glândula Tireoide/terapia , Estudos de Coortes , Feminino , Seguimentos , França/epidemiologia , Humanos , Metástase Linfática , Masculino , Análise por Pareamento , Pessoa de Meia-Idade , Esvaziamento Cervical , Dosagem Radioterapêutica , Estudos Retrospectivos , Câncer Papilífero da Tireoide/patologia , Neoplasias da Glândula Tireoide/patologia , Tireoidectomia , Estados Unidos/epidemiologia
4.
Surg Endosc ; 32(12): 4867-4873, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-29766309

RESUMO

BACKGROUND: The use of the robotic platform has not been well established in patients with super obesity (SO; body mass index, BMI ≥ 50) and super-super obesity (SSO, BMI ≥ 60). We aimed to determine safety and feasibility of robotic bariatric surgery in this cohort. METHODS: Review of a prospectively maintained database was performed of consecutive patients undergoing robotic bariatric surgery between 2015 and 2017. Propensity score analysis with 1:2 nearest neighbor matching was performed to control for baseline characteristics and procedure type. RESULTS: A propensity-matched cohort of 47 SO patients (median BMI 55.3, range 50.1-92.5) and 94 morbidly obese (MO; median BMI 41.8, range 35.1-48.8) patients were analyzed. After matching, there were no difference in baseline characteristics including age, American Society of Anesthesiologists (ASA) score, or preoperative comorbidities. Most patients in each group underwent sleeve gastrectomy (81% of SO patients versus 76% of MO patients) or Roux-en-Y gastric bypass (13% vs. 18%, respectively), p = 0.66. There were no differences in operative time, intraoperative complications, postoperative complications, or re-admissions between groups. Length of stay was slightly longer in the MO group (2.2 days, IQR 1.8-3.2 vs. 1.8 days, IQR 1.2-2.7; p = 0.01). A subset of SSO patients (n = 11, median BMI 67, range 60-92) was analyzed; there was no increase in operation time, and zero intraoperative complications, conversions to open, or postoperative complications in this subset. CONCLUSIONS: Robotic bariatric surgery can safely be performed on patients with SO or SSO with low perioperative morbidity and no increase in operating time.


Assuntos
Obesidade Mórbida/cirurgia , Procedimentos Cirúrgicos Robóticos , Adulto , Manuseio das Vias Aéreas , Estudos de Viabilidade , Feminino , Gastrectomia , Derivação Gástrica , Humanos , Laparoscopia , Tempo de Internação/estatística & dados numéricos , Masculino , Análise por Pareamento , Bloqueio Nervoso , Duração da Cirurgia , Complicações Pós-Operatórias , Pontuação de Propensão , Estudos Retrospectivos
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